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The effect of training on physical capacity during unilateral limb unloading in humans

Research Project

Project/Area Number 17300207
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionNagoya University

Principal Investigator

HIROSHI Akima  Nagoya University, 総合保健体育科学センター, 准教授 (40292841)

Co-Investigator(Kenkyū-buntansha) ISHIDA Koji  名古屋大学, 総合保健体育科学センター, 教授 (50193321)
KATAYAMA Keisho  名古屋大学, 総合保健体育科学センタ, 准教授 (40343214)
SAKUMA Kunihiro  豊橋技術科学大学, 体育保健センター, 准教授 (60291176)
増田 和実  金沢大学, 教育学部, 准教授 (50323283)
宮地 元彦  独立行政法人国立健康・栄養研究所, 身体活動調査研究室, 室長 (60229870)
Co-Investigator(Renkei-kenkyūsha) MASUDA Kazumi  金沢大学, 教育学部, 准教授 (50323283)
MIYACHI Motohiko  国立健康, 栄養研究所, 身体活動調査研究 (60229870)
Project Period (FY) 2005 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥16,800,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2008: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2007: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2006: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2005: ¥4,200,000 (Direct Cost: ¥4,200,000)
Keywords宇宙医学 / 対抗措置 / 運動機能 / 骨格筋 / 呼吸循環系 / 筋機能 / 筋萎縮 / 不活動モデル / 運動トレーニング / 宇宙滞在 / 呼吸循環機能 / 下肢サスペンジョン / 骨格筋成長因子 / 身体不活動
Research Abstract

ヒトが宇宙で滞在することによって生じる身体機能の減退を防ぐため, どのようなトレーニングが効果的であるのかについて地上モデルを用いて検討した。実験期間中に片脚に体重をかけないようにする宇宙滞在モデルを用いて, 高強度インターバルトレーニングを一日おきあるいは二日おき, 高強度インターバル+筋力トレーニングを一日おきに行った。その結果, 一日おきに高強度インターバル+筋力トレーニングを行うと筋力, 筋量, 呼吸循環系などの運動機能を全般的に維持できることが示された.

Report

(5 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (45 results)

All 2009 2008 2007 2006 2005 Other

All Journal Article (20 results) (of which Peer Reviewed: 9 results) Presentation (24 results) Remarks (1 results)

  • [Journal Article] Cycle ergometer exercise counteract muscle atrophy during unilateral lower limb suspension.2009

    • Author(s)
      Hiroshi Akima, et al.
    • Journal Title

      Aviat. Space Environ. Med. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of intensive interval training during unloading on muscle oxygenation kinetics.2009

    • Author(s)
      Yasuro Furuichi, et al.
    • Journal Title

      Int. J. Sports Med. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cross-talk from adjacent muscle has a negligible effect on surface electromyographic activity of vastus intermedius muscle during isometric contraction.2009

    • Author(s)
      Kohei Watanabe, Hiroshi Akima
    • Journal Title

      J. Electromyogr. Kinesiol. (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-related reductions in expression of serum response factor and myocardin-related transcription factor A in mouse skeletal muscles.2008

    • Author(s)
      Kunihiro Sakuma
    • Journal Title

      Biochimica Biophysica Acta (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of unloading on muscle volume with and without resistance training2007

    • Author(s)
      Hiroshi Akima
    • Journal Title

      Acta Astronaut 60

      Pages: 728-736

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of 20-day bed rest with and without strength training on postural sway during quite standing2007

    • Author(s)
      Motoki Kouzaki
    • Journal Title

      Acta Physiol 189

      Pages: 279-292

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of 20-day bed rest with and without strength training on postural sway during quite standing.2007

    • Author(s)
      Kouzaki, M., Masani, K., Akima, H., Shirasawa, H., Fukuoka, H., Kanehisa, H., Fukunaga, T.
    • Journal Title

      Acta Physiol. 189

      Pages: 279-292

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effect of unloading on muscle volume with and without resistance training.2007

    • Author(s)
      Akima, H., Ushiyama, J., Kubo, J., Fukuoka, H., Kanehisa, H., Fukunaga, T
    • Journal Title

      Acta Astronaut. 60

      Pages: 728-736

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Oxygen uptake kinetics following 20 days of unilateral lower limb suspension2006

    • Author(s)
      Hotta, N, Sato, K, Katayama, K, Koga, S, Masuda, K, Miyachi, M, Akima, H, Ishida, K.
    • Journal Title

      J. Physiol. Sci 56

      Pages: 347-353

    • NAID

      10019380103

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxygen uptake kinetics following 20 days of unilateral lower limb suspension.2006

    • Author(s)
      Hotta, N., Sato, K., Katayama, K., Koga, S., Masuda, K., Miyachi, M., Akima, H., Ishida, K
    • Journal Title

      J. Physiol. Sci. 56

      Pages: 347-353

    • NAID

      10019380103

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest.2006

    • Author(s)
      Ogawa, T., Furochi, H., Mameoka, M., Hirasaka, K., Suzue, N., Oarada, M., Akamatsu, M., Akima, H., Fukunaga, T., Kishi, K., Yasui, N., Fukuoka, H., Nikawa, T.
    • Journal Title

      Muscle & Nerve 34

      Pages: 463-469

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Muscle soreness and damage augment ventilatory response at the onset of exercise.2006

    • Author(s)
      Hotta, N., Sato, K., Sun, Z., Katayama, K., Akima, H., Kondo, T., Ishida, K.
    • Journal Title

      Eur. J. Appl. Physiol. 97

      Pages: 598-606

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Recruitment of the thigh muscles during sprint cycling by muscle functional magnetic resonance imaging.2005

    • Author(s)
      Akima, H., Kinugasa, R., Kuno, S.
    • Journal Title

      Int.J.Sports Med 26

      Pages: 245-252

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Neuromuscular activation o triceps surae using muscle functional MRI and EMG.2005

    • Author(s)
      Kinugasa, R., Akima, H.
    • Journal Title

      Med.Sci.Sports Exerc. 37

      Pages: 593-598

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Intensive cycle training with artificial gravity maintains muscle size during bed rest.2005

    • Author(s)
      Akima, H., et al.
    • Journal Title

      Aviat.Space Environ.Med. 76

      Pages: 923-929

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Atrophy of thigh muscles after meniscal lesions and arthroscopic partial meniscectomy.2005

    • Author(s)
      Akima, H., Furukawa, T.
    • Journal Title

      Knee Surg.Sports Traumatol.Arthrosc. 13

      Pages: 632-637

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Functional imaging of human skeletal muscle during movement : Implications for recruitment, metabolism and circulation.2005

    • Author(s)
      Akima, H.
    • Journal Title

      Int.J.Sport Health Sci. 13

      Pages: 193-206

    • NAID

      130000069679

    • Related Report
      2005 Annual Research Report
  • [Journal Article] ergometer exercise to counteract muscle atrophy during unilateral lower limb suspension

    • Author(s)
      Akima, H, Hotta, N, Sato, K, Ishida, K, Koike, T, Katayama, K.
    • Journal Title

      Aviat. Space Environ. Med. (accepted for publication)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of intensive interval training during unloading on muscle oxygenation kinetics

    • Author(s)
      Furuichi, Y, Masuda, K, Takakura, H, Hotta, N, Ishida, K, Katayama, K, Iwase, S, Akima, H.
    • Journal Title

      Int. J. Sports Med. (accepted for publication)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thigh muscle activation distribution and pulmonary Vo2 kinetics during moderate, heavy and severe intensity cycling exercise in humans.

    • Author(s)
      Yamaoka-Endo, M., Kobayakawa, M., Kinugasa, R., Kuno, S., Akima, H., Rossiter, H.B., Miura, A., Fukuba, Y.
    • Journal Title

      Am. J. Physiol. Regul. Integr. Comp. Physiol. (in press)

    • Related Report
      2006 Annual Research Report
  • [Presentation] 片脚サスペンジョン中のインターバルおよびレッグプレストレーニングが筋機能・形態に及ぼす影響2008

    • Author(s)
      秋間広
    • Organizer
      第63回日本体力医学会
    • Place of Presentation
      大分
    • Year and Date
      2008-09-18
    • Related Report
      2008 Final Research Report
  • [Presentation] Effects of low frequency intensive interval training on muscle atrophy and function during unloading2008

    • Author(s)
      Akima, H.
    • Organizer
      The 55th Annual Meeting of American College of Sports Medicine
    • Place of Presentation
      Indianapolis, IN, USA
    • Year and Date
      2008-05-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Intensive interval training prevents muscle atrophy during unloading2008

    • Author(s)
      Hiroshi Akima
    • Organizer
      American College of Sports Medicine
    • Place of Presentation
      Indianapolis, IN, USA
    • Year and Date
      2008-05-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 片脚サスペンジョン中のインターバルトレーニングが漸増負荷運動時の筋動員に及ぼす影響2007

    • Author(s)
      渡邊航平
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-14
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of intensive interval training during unilateral lower limb unloading on aerobic capacity2007

    • Author(s)
      Katayama, K.
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-14
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョン中のインターバルトレーニングが有酸素性運動能力に及ぼす影響ートレーニング頻度の違いによる影響についてー2007

    • Author(s)
      片山敬章
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-14
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョン中の低頻度インターバルトレーニングが筋機能・形態に及ぼす影響2007

    • Author(s)
      秋間 広
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-14
    • Related Report
      2008 Final Research Report
  • [Presentation] 片足サスペンジョン中のインターバルトレーニングが下肢筋酸素動態に及ぼす影響2007

    • Author(s)
      古市泰郎
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-14
    • Related Report
      2008 Final Research Report
  • [Presentation] Intensive interval training prevents muscle atrophy during unloading2007

    • Author(s)
      Hiroshi Akima
    • Organizer
      American College of Sports Medicine
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effect of intensive interval training during unilateral lower limb unloading on the muscle oxygenation kinetics2007

    • Author(s)
      Furuichi, Y.
    • Organizer
      The 54th Annual Meeting of American College of Sports Medicine
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2007-05-31
    • Related Report
      2008 Final Research Report
  • [Presentation] Intensive interval training prevents muscle atrophy during unloading2007

    • Author(s)
      Akima, H.
    • Organizer
      The 54th Annual Meeting of American College of Sports Medicine
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2007-05-31
    • Related Report
      2008 Final Research Report
  • [Presentation] シンポジウム : 身体不活動による筋萎縮と運動処方2007

    • Author(s)
      秋間広
    • Organizer
      第11回日本体力医学会東海地方会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-03-18
    • Related Report
      2008 Final Research Report
  • [Presentation] 局所的不活動による血管機能低下に対するインターバルトレーニングの抑制効果2006

    • Author(s)
      河野 寛
    • Organizer
      第61回日本体力医学会
    • Place of Presentation
      神戸
    • Year and Date
      2006-09-26
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョン中のインターバルトレーニングが運動時の呼吸循環応答に及ぼす影響2006

    • Author(s)
      佐藤耕平
    • Organizer
      第61回日本体力医学会
    • Place of Presentation
      神戸
    • Year and Date
      2006-09-25
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョン中のインターバルトレーニングが筋機能・形態に及ぼす影響2006

    • Author(s)
      秋間 広
    • Organizer
      第61回日本体力医学会
    • Place of Presentation
      神戸
    • Year and Date
      2006-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] The influence of unilateral lower limb suspension on cardiorespiratory response during exercise2006

    • Author(s)
      Sato, K.
    • Organizer
      The 53rd Annual Meeting of American College of Sports Medicine
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2006-05-31
    • Related Report
      2008 Final Research Report
  • [Presentation] Unilateral lower limb suspension induced atrophy as a model of unweighting2006

    • Author(s)
      Akima, H.
    • Organizer
      The 27th International Gravitational Physiology Meeting
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2006-04-25
    • Related Report
      2008 Final Research Report
  • [Presentation] 下肢サスペンジョンおよびベッドレストによる筋萎縮の比較2005

    • Author(s)
      秋間広
    • Organizer
      第51回日本宇宙航空環境医学会
    • Place of Presentation
      神奈川
    • Year and Date
      2005-11-12
    • Related Report
      2008 Final Research Report
  • [Presentation] 20日間の片脚サスペンジョンが運動時の呼吸循環応答に及ぼす影響2005

    • Author(s)
      佐藤耕平
    • Organizer
      第16回日本女子体育大学附属基礎体力研究所研究フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2005-10-15
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョンによる運動時の呼吸循環応答の変化2005

    • Author(s)
      佐藤耕平
    • Organizer
      第60回日本体力医学会
    • Place of Presentation
      岡山
    • Year and Date
      2005-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョンによるヒト骨格筋の機能と形態の変化2005

    • Author(s)
      秋間 広
    • Organizer
      第60回日本体力医学会
    • Place of Presentation
      岡山
    • Year and Date
      2005-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 片脚サスペンジョンによる運動開始直後の呼吸・循環応答の変化2005

    • Author(s)
      石田浩司
    • Organizer
      第60回日本体力医学会
    • Place of Presentation
      岡山
    • Year and Date
      2005-09-23
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of unilateral lower limb suspension on the oxygen uptake kinetics at the start of exercise2005

    • Author(s)
      Hotta, N.
    • Organizer
      The 6th International Head-Out Water Immersion Symposium
    • Place of Presentation
      Aichi, Japan
    • Year and Date
      2005-09-20
    • Related Report
      2008 Final Research Report
  • [Presentation] Neuromuscular adaptations to unilateral lower limb suspension in humans2005

    • Author(s)
      Akima, H.
    • Organizer
      The 6th International Head-Out Water Immersion Symposium
    • Place of Presentation
      Aichi, Japan
    • Year and Date
      2005-09-20
    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://www.htc.nagoya-u.ac.jp/~akima/

    • Related Report
      2008 Final Research Report

URL: 

Published: 2005-04-01   Modified: 2016-04-21  

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