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Establishment of exercise guideline for healthy middle-aged and older adults : effective training against both care and cardiovascular disease.

Research Project

Project/Area Number 17300226
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionNational Institute of Health and Nutrition

Principal Investigator

MIYACHI Motohiko  National Institute of Health and Nutrition, Health Promotion and Exercise Program, Ph.D, Project Leader (60229870)

Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥16,130,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2007: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2006: ¥5,100,000 (Direct Cost: ¥5,100,000)
Fiscal Year 2005: ¥4,400,000 (Direct Cost: ¥4,400,000)
Keywordsarterial stiffness / care prevention / life-style related diseases / combined training / endothelial function / muscular strength / endurance / 筋力トレーニング / 介護 / 生活習慣病 / 動脈スティフネス / 筋法力維持法
Research Abstract

Older individuals are at greater risks for development of cardiovascular disease as well as for having functional disability associated with sarcopenia (age-related loss of muscle mass and strength), and resistance training is being strongly recommended as a preventive intervention for functional capacity with advancing age. We previously indicated that, in marked contrast to the beneficial effect of regular aerobic exercise, several months of resistance training "increases" central arterial stiffness in healthy men. This study aimed to determine the effects of moderate resistance training as well as the combined resistance and aerobic training intervention on carotid arterial stiffness. Thirty-nine young healthy men were assigned either to the moderate-intensity resistance training (MODE), the combined resistance training and endurance training (COMBO) or the sedentary control (CONTROL) groups. Participants m the training groups underwent three training sessions per week for 4 months followed by four additional months of detraining. All training groups increased maximal strength in all the muscle groups tested (P<0.05). Carotid arterial compliance (via simultaneous carotid ultrasound and applanation tonometry) decreased approximately 20% after MODE training (from 0.20+/- 0.01 to 0.16+/0.01 mm2/mmHg, P<0.01). No significant changes in carotid arterial compliance were observed in the COMBO (0.20+/0.01 to 0.23+/0.01mm2/mmHg) and CONTROL (0.20+/0.01 to 0.20+/0.01mm2/mmHg) groups. Following the detraining period, carotid arterial compliance returned to the baseline level. Peripheral (femoral) artery compliance did not change m any groups. We concluded that simultaneously performed aerobic exercise training could prevent the stiffening of carotid arteries caused by resistance training in young healthy men. Based on these findings, we recommend combined training as an training method that is effective for both care prevention and cardiovascular disease prevention.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report

Research Products

(26 results)

All 2008 2007 2006 2005

All Journal Article Presentation Book

  • [Journal Article] Resistance training in men is associated with increased arterial stiffness and blood pressure but does not adversely affect endothelial function as measured by arterial reactivity to the cold pressor test.2008

    • Author(s)
      Kawano H, Tanimoto M, Yamamoto K, Sanada K, Gando Y, Tabata I, Higuchi M, Miyachi M.
    • Journal Title

      Exp Physiol 93

      Pages: 296-302

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Resistance training in men is associated with increased arterial stiffness and blood pressure but does not adversely affect endothelial function as measured by arterial reactivity to the cold pressor test.2008

    • Author(s)
      Kawano H, Tanimoto M, Yamamoto K, Sanada K, Gando Y, Tabata I, Higuchi M, Miyachi M
    • Journal Title

      Experimental Physiology 93(2)

      Pages: 296-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Resistance training in men is associated with increased arterial stiffnessand blood pressure but does not adversely affect endothelial functionas measured by arterial reactivity to the cold pressor test2008

    • Author(s)
      Kawano H, Tanimoto M, Yamamoto K, Sanada K, Gando Y;Tabata I, Higuchi M, Miyachi M.
    • Journal Title

      Exp Physiol 93

      Pages: 296-302

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高血圧症、特集 生活習慣病の発症機序と身体活動・運動2007

    • Author(s)
      宮地元彦、家光素行、村上晴香
    • Journal Title

      体育の科学 57

      Pages: 881-887

    • NAID
      40015720560
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of age on ventilatory threshold and peak oxygen uptake normalised for regional skeletal muscle mass in Japanese men and women aged 20-80 years .2007

    • Author(s)
      Sanada K, Kuchiki T, Miyachi M, McGrath K, Higuchi M, Ebashi H
    • Journal Title

      European Journal of Applied Physiology 99(5)

      Pages: 475-483

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 高血 圧症、特集 生活習慣病の発症機序と身体活動・運動2007

    • Author(s)
      宮地 元彦、家光 素行、村上 晴香
    • Journal Title

      体育の科学 57

      Pages: 881-887

    • NAID
      40015720560
    • Related Report
      2007 Annual Research Report
  • [Journal Article] Oxygen uptake kinetics following 20 days of unilateral lower limb suspension.2007

    • Author(s)
      Hotta N, Sato K, Katayama K, Koga S, Masuda K, Miyachi M, Akima H, Ishida K
    • Journal Title

      J Physiol Sci. 56

      Pages: 347-353

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Resistance training and arterial compliance: keeping the benefits while minimizing the stiffening.2006

    • Author(s)
      Kawano H, Tanaka H, Miyachi M.
    • Journal Title

      J Hypertens 24

      Pages: 1753-1759

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Resistance Training and Arterial Compliance : Keeping the Benefits While Minimizing the Stiffening.2006

    • Author(s)
      Kawano H, Tanaka H, Miyachi M
    • Journal Title

      Journal of Hypertension 24(9)

      Pages: 1753-1759

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Resistance training and arterial compliance:keeping the benefits whieminimizing the stiffening2006

    • Author(s)
      Kawano H, Tanaka H, Miyachi M.
    • Journal Title

      J Hypertens 24

      Pages: 1753-1759

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Resistance training and arterial compliance : keeping the benefits while minimizing the stiffening.2006

    • Author(s)
      Kawano H, Tanaka H, Miyachi M
    • Journal Title

      J Hypertens. 24・4

      Pages: 1753-1759

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 生活習慣病予防のための体力 : 特集 新しい健康づくりのための運動基準・指針、宮地元彦 : 健康増進プログラム2006

    • Author(s)
      宮地元彦
    • Journal Title

      体育の科学 56・8

      Pages: 608-614

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Fluctuations in carotid arterial distensibility during the menstrual cycle do not influence cardiovagal baroreflex sensitivity.2006

    • Author(s)
      Hayashi K, Miyachi M, Seno N, Takahashi K, Yamazaki K, Sugawara J, Yokoi T, Onodera S, Mesaki N.
    • Journal Title

      Acta Physiol (Oxf) 186・2

      Pages: 103-110

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Variations in carotid arterial compliance during the menstrual cycle in young women.2006

    • Author(s)
      Hayashi K, Miyachi M, Seno N, Takahashi K, Yamazaki K, Sugawara J, Yokoi T, Onodera S, Mesaki N.
    • Journal Title

      Exp Physiol. 91・2

      Pages: 465-472

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Lack of Age-Related Decreases in Basal Whole-Leg Blood Flow in Resistance Trained Men2005

    • Author(s)
      Miyachi M, Tanaka H, Kawano H, Okajima M, Tabata I
    • Journal Title

      J Appl Physiol 99・4

      Pages: 1384-1390

    • Related Report
      2005 Annual Research Report
  • [Presentation] 動脈の老化とその予防のための運動〜保健指導に向けて〜2007

    • Author(s)
      宮地元彦
    • Organizer
      第30回 日本高血圧学会総会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2007-10-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 動脈の老化とその予防のための運動〜保健指導に向けて〜2007

    • Author(s)
      宮地 元彦
    • Organizer
      第30回 日本高血圧学会総会
    • Place of Presentation
      沖縄コンペンションセンター
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Age, Flexibility, and Metabolic Syndrome2007

    • Author(s)
      Miyachi M, Sanada K, Yamamoto K, Kawano H, Gando Y, Tanimoto M, Oh T, Ohmori Y, Higuchi M, Tabata I
    • Organizer
      ACSM 54th Annual Meeting
    • Place of Presentation
      New Orleans, Lousiana
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Resistance Training and Arterial Compliance : Keeping the Benefits While Minimizing the Stiffening2006

    • Author(s)
      Miyachi M, Kawano H, Tanaka H
    • Organizer
      ACSM Conference on Integrative Physiology of Exercise
    • Place of Presentation
      Austin, Texas
    • Year and Date
      2006-09-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] メタボ解消!10分エクササイズon DVD2008

    • Author(s)
      Miyachi M, Okamoto S, Mifune T, Niikura K
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 介護予防のためのマシンを使わない筋力向上トレーニング(DVD, ハンドブック)2007

    • Author(s)
      太田壽城、津下一代、宮地元彦, 他
    • Publisher
      介護予防のためのマシンを使わない筋力向上トレーニング
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 介護予防のためのマシンを使わない筋力向上トレーニング2007

    • Author(s)
      Ohta T, Tsushita K, Miyashi M, Uchida S, Ishikawa H, Higasiuchi K
    • Publisher
      健康・体力づくり事業財団(DVD, ハンドブック)
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 「病気予防」百科2007

    • Author(s)
      Miyachi M, Kubo A
    • Publisher
      日本医療企
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 介護予防のためのマシンを使わない筋力向上トレーニング(DVD, ハンドブック)2007

    • Author(s)
      太田 壽城、津下 一代、宮地 元彦, 他
    • Publisher
      介護予防のためのマシンを使わない筋力向上トレーニング
    • Related Report
      2007 Annual Research Report
  • [Book] 介護予防のためのマシンを使わない筋力向上トレーニング(DVD,ハンドブック)2007

    • Author(s)
      太田壽城, 津下一代, 宮地元彦, 内田滋, 石川裕哲, 東内京一
    • Publisher
      健康・体力づくり事業財団
    • Related Report
      2006 Annual Research Report
  • [Book] 運動とPWV:PWVを知るPWVで診る2006

    • Author(s)
      Miyachi M
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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