| Project/Area Number |
17360377
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Properties in chemical engineering process/Transfer operation/Unit operation
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| Research Institution | Kagoshima University |
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Principal Investigator |
HATATE Yasuo Kagoshima University, Faculty of Engineering, Professor (00038051)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Masahiro Kagoshima University, Faculty of Engineering, Associate Professor (50315397)
AIKOU Ryoko Kagoshima University, Faculty of Engineering, Technical Assistant (50244265)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥15,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2007: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2006: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2005: ¥9,500,000 (Direct Cost: ¥9,500,000)
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| Keywords | Microencapsulation / Liquid crystal / Interfacial polymerization / Solvent evaporation / microsphere / Electro response / 強誘電性 |
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| Research Abstract |
Microcapsules have been drawing much attention as intelligent materials. In particular, functionalized polymeric microcapsules are eagerly studied in the chemical and industrial fields. Microcapsule membranes are semipermeable and therefore have disadvantage in that they cannot trap small substances in the inner phase. To overcome, we prepared a novel functionalized polystyrene microcapsule whose porous membrane was corked with ferroelectric liquid crystalline segments.
In this study, we prepared microcapsule with the ferroelectric liquid crystal, and investigated in detail the permeability control of oxprenolol, a model encapsulated drug, through the membrane of an electro-receptive nylon-polystyrene microcapsule^<1'2>). In addition, the permeability mechanism, with or without the electrical field, was quantitatively characterized by means of polarized light transmittance measurement. We specifically investigated the changes in behavior of the liquid crystalline segment of the microcapsule membrane under an electrical field.
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