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Chemotherapy with hybrid liposomes and application to drug delivery system with hybrid liposomes

Research Project

Project/Area Number 17360403
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biofunction/Bioprocess
Research InstitutionSojo University

Principal Investigator

UEOKA Ryuichi  Sojo University, Faculty of Biotechnology and Life Science, Professor (70099076)

Co-Investigator(Kenkyū-buntansha) MATSUMOTO Yoko  Sojo University, Faculty of Biotechnology and Life Science, Professor (00133562)
MATSUSHITA Taku  Sojo University, Faculty of Biotechnology and Life Science, Professor (10209538)
ICHIHARA Hideaki  Sojo University, Faculty of Biotechnology and Life Science, Research Assistant (70369114)
金納 明宏  (株)薬物安全性試験センター薬理研究所, 取締役
Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥16,380,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2007: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2006: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2005: ¥8,100,000 (Direct Cost: ¥8,100,000)
Keywordsliposome / chemotherapy / apoptosis / antitumor effect / fusion / fluidity / drug delivery system / muscular dystrophy / リポソーム(複合脂質膜) / 制がん効果 / リポゾーム(複合脂質膜)
Research Abstract

We have produced hybrid liposomes (HL) which can be prepared by sonication of vesicular and micellar molecules in a buffer solution. The physical properties of HL such as size, shape, membrane fluidity, and the temperature of phase separation can be controlled by changing the constituents and compositional ratio. We have employed HL for the research of cancers and interesting results are as follows;
(A) The uniform and stable structure of HL composed of dimyristoylphosphatidylcholine (DMPC) and polyoxyethylene (23)-dodecyl ether (C12 (E0) 2) with a diameter of 80 nm was revealed on the basis of electron microscopy and dynamic light scattering measurements.
(B) The remarkable inhibitory effects of HL on the growth of human-B-lymphoma (RAJI) cells were attained. Induction of apoptosis by HL was obtained using flow cytometry, DNA agarose gel electrophoresis, micrograph with TUNEL method and time-laps video.
(C) Significantly prolonged survival and remarkable reduction of tumor volume were obtained using mice model of carcinoma after the treatment with HL without any drug.
(D) There were no abnormal findings on blood test, hemato chemistry, relative organ weight and autopsy of normal rats after administering HL on the basis of chronic toxicity tests.
(E) In clinical applications, prolonged survival was attained in patients with lymphoma after the intravenous injection of HL without any side effect and remarkable reduction of neoplasm was obtained after the local administration of hybrid liposomes.
(F) Remarkable immunostimulation effects of HL on human peripheral blood mononuclear cells were obtained in vitro.
(G) A novel approach of gentamicin therapy for Duchenne Muscular Dystrophy using HL was examined. Mdx mice treated with gentamicin encapsulated HL did not show toxicity and the efficiency of dystrophin positive fibers in the mdx mice injected with gentamicin encapsulated HL was obtained.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (117 results)

All 2008 2007 2006 2005 Other

All Journal Article (40 results) (of which Peer Reviewed: 15 results) Presentation (65 results) Book (10 results) Remarks (2 results)

  • [Journal Article] 糖含有三成分系ハイブリッドリポソームの物性と制がん効果に関する基礎研究2008

    • Author(s)
      田中 芳浩
    • Journal Title

      高分子論文集 65

      Pages: 90-97

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Specific Fixed Aqueous Layer of Three-component Hybrid Liposomes Related to Inhibition of Hepatoma Cells Growth2008

    • Author(s)
      Yoko Matsumoto
    • Journal Title

      Chemistry Letters 37

      Pages: 118-119

    • NAID

      10020148380

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Induction of Apoptosis of Human Tumor Cells by Hybrid Liposomes Including Docosahexaenoic Acid2008

    • Author(s)
      Koichi Goto
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 18

      Pages: 1880-1883

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Remarkably High Inhibitory Effects of Docosahexaenoic Acid Incorporated into Hybrid Liposomes on the Growth of Tumor Cells along with Apoptosis2008

    • Author(s)
      Yoshihiro Tanaka
    • Journal Title

      International Journal of Pharmaceutics (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Chemotherapy Using Hybrid Liposomes along with Induction of Apoptosis2008

    • Author(s)
      Hideaki Ichihara
    • Journal Title

      Anticancer Research (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Physical Properties and Inhibitory effects of Three-component Hybrid Liposomes Including Sugar Surfactants2008

    • Author(s)
      Yoshihiro Tanaka, Koichi Goto, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      KOBUNSHI RONBUNSHU, Peer-reviewed original paper 65

      Pages: 90-97

    • NAID

      10020123755

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Specific Fixed Aqueous Layer ofThree-component Hybrid Liposomes Related to Inhibition of Hepatoma Cells Growth2008

    • Author(s)
      Yoko Matsumoto, Yoshihiro Tanaka, Koichi Goto, Ryuichi Ueoka
    • Journal Title

      Chemistry Letters, Peer-reviewed original paper 37

      Pages: 118-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Induction of Apoptosis of Human Tumor Cells by Hybird Liposomes Including Docosahexaenoic Acid2008

    • Author(s)
      Koichi Goto, Yoshihiro Tanaka, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters Peer-reviewed original paper 18

      Pages: 1880-1883

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Remarkably High Inhibitory Effects of Docosahexaenoic Acid Incorporated into Hybrid Liposomes on the Growth ofTumor Cells along with Apoptosis2008

    • Author(s)
      Yoshihiro Tanaka, Koichi Goto, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      International Journal of Pharmaceutics, Peer-reviewed original paper (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Chemotherapy Using Hybrid Liposomes along with Induction of Apoptosis2008

    • Author(s)
      Hideaki Ichihara, Hideaki Nagami, Tetsuyuki Kiyokawa, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      nticancer Res., Peer-reviewed original paper (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Remarkable immunostimulation effects of hybrid liposomes on human peripheral blood mononuclear cells in vitro2007

    • Author(s)
      Yuji Komizu
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 17

      Pages: 613-616

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Remarkable Immunostimulation Effects ofHybrid Liposomes on Human Peripheral Blood Mononuclear Cells in Vitro2007

    • Author(s)
      Yuji Komizu, Yuka Tomonaga, Koichi Goto, Ryuichi Ueoka
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters Peer-reviewed original paper 17

      Pages: 613-616

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Induction and High Density Culture of Human Hepatoblasts from Fetal Hepatocytes with Suppressing Transformation2007

    • Author(s)
      Akifumi Kiyota
    • Journal Title

      Biological & Pharmaceutical Bulletin 30

      Pages: 2308-2311

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Remarkable immunostimulation effects of hybrid liposomes on human peripheral blood mononuclear cells in vitro2007

    • Author(s)
      Yiji Komizu
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 17・3

      Pages: 613-616

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Two Methylene Groups in Phospholipids Distinguish between Apoptosis and Necrosis for Tumor Cells2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 16

      Pages: 782-785

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Induction of Apoptosis by Hybrid Liposomes for Human Breast Tumor Cells along with Activation of Caspases2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      Biological & Pharmaceutical Bulletin 29

      Pages: 379-380

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Chemotherapy with hybrid liposomes for lymphoma without drugs in vivo2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      International Journal of Pharmaceutics 315

      Pages: 167-172

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Membrane targeted chemotherapy with hybrid liposomes for colon tumor cells leading to apoptosis2006

    • Author(s)
      Yuji Komizu
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 16

      Pages: 6131-6134

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Induction of Apoptosis by Hybrid Liposomes for Human Breast Tumor Cells along with Activation of Caspases.2006

    • Author(s)
      Hideaki Nagami, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Biological & Pharmaceutical Bulletin, Peer-reviewed original paper 29

      Pages: 379-380

    • NAID

      110005663977

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Two Methylene Groups in Phospholipids Distinguish between Apoptosis and Necrosis for Tumor Cells2006

    • Author(s)
      Hideaki Nagami, Koji Nakano, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters, Peer-reviewed original paper 16

      Pages: 782-785

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Chemotherapy with hybrid liposomes for lymphoma without drugs in vivo2006

    • Author(s)
      Hideaki Nagami, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Int. J. Pharm., Peer-reviewed original paper 315

      Pages: 167-172

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Membrane Targeted Chemotherapy with Hybrid Liposomes for Colon Tumor Cells Leading to Apoptosis2006

    • Author(s)
      Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters Peer-reviewed original paper 16

      Pages: 6131-6134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Chemotherapy with hybrid liposomes for lymphoma without drugs in vivo2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      International Journal of Pharmaceutics 315・1-2

      Pages: 167-172

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Membrane targeted chemotherapy with hybrid liposomes for colon tumor cells leading to apoptosis2006

    • Author(s)
      Yiji Komizu
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 16・23

      Pages: 6131-6134

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Two Methylene Groups in Phospholipids Distinguish between Apoptosis and Necrosis for Tumor Cells2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      Bioorganic & medicinal chemistry letters 16・4

      Pages: 782-785

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Induction of Apoptosis by Hybrid Liposomes for Human Breast Tumor Cells along with Activation of Caspases.2006

    • Author(s)
      Hideaki Nagami
    • Journal Title

      Biological & pharmaceutical bulletin 29・2

      Pages: 379-380

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Induction of Apoptosis of Human Lung Carcinoma Cells by Hybrid Liposomes Containing Polyoxyethylenedodecyl Ether2005

    • Author(s)
      Yasunori Iwamoto
    • Journal Title

      International Journal of Pharmaceutics 292

      Pages: 231-239

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Novel Mechanism of Hybrid Liposomes-Induced Apoptosis in Human Tumor Cells2005

    • Author(s)
      Yoko Matsumoto
    • Journal Title

      International Journal of Cancer 115

      Pages: 377-382

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] アポトーシス誘導ハイブリッドリポソームによるがん治療2005

    • Author(s)
      松本 陽子
    • Journal Title

      膜 30

      Pages: 304-307

    • NAID

      10016855093

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ハイブリッドリポソーム単独投与による神経芽腫肝転移抑制効果2005

    • Author(s)
      根岸 由香
    • Journal Title

      小児外科学会雑誌 41

      Pages: 930-937

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Induction ofApoptosis ofHuman Lung Carcinoma Cells by Hybrid Liposomes Containing Polyoxyethylenedodecyl Ether2005

    • Author(s)
      Yasunori Twamoto, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      International Journal of Pharmaceutics, Peer-reviewed originalpaper 292

      Pages: 231-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Novel Mechanism of Hybrid Liposomes-Induced Apoptosis in Human Tumor Cells2005

    • Author(s)
      Yoko Matsumoto, Yasunori Iwamoto, Ryuichi Ueoka
    • Journal Title

      International Journal of Cancer, Peer-reviewed original paper 115

      Pages: 377-382

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Inhibitory Effect of Drug Free Hybrid Liposomes on Metastasis of Mouse Neuroblastoma2005

    • Author(s)
      Yuka Negishi, Joji Yoshizawa, Yoji Yamazaki, Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Journal ofthe Japanese Society of Pediatric Surgeons., Peer-reviewed original paper 41

      Pages: 930-937

    • NAID

      110002975391

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Chemotherapy with Hybrid Liposomes Leading toApoptosis for Colon Tumor Cells2005

    • Author(s)
      Yoko Matsumoto, Ryuichi Ueoka
    • Journal Title

      Vlembrane, Peer-reviewed original paper 30

      Pages: 304-307

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Induction of Apoptosis of Human Lung Carcinoma Cells by Hybrid Liposomes Containing Polyoxyethylenedodecyl Ether2005

    • Author(s)
      Yasunori Iwamoto
    • Journal Title

      International Journal of Pharmaceutics 292・2

      Pages: 231-239

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Novel Mechanism of Hybrid Liposomes-Induced Apoptosis in Human Tumor Cells2005

    • Author(s)
      Yasunori Iwamoto
    • Journal Title

      International Journal of cancer 115・3

      Pages: 377-382

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Inhibitory Effects of Extracts from Shochu Distillation Remnants on the Growth of Human Stomach Tumor Cells2005

    • Author(s)
      Yutaka Kadota
    • Journal Title

      Journal of Chemical Engineering of Japan 38・2

      Pages: 154-157

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Marked Inhibitory Effects of Extracts from Barley-Koji Miso Encapsulated in Hybrid Liposomes on the Growth of Human Stomach Tumor Cells in Vitro2005

    • Author(s)
      Yutaka Kadota
    • Journal Title

      Chemistry letters 34・3

      Pages: 370-371

    • Related Report
      2005 Annual Research Report
  • [Journal Article] アポトーシス誘導ハイブリッドリポソームによるがん治療2005

    • Author(s)
      松本陽子
    • Journal Title

      膜 30・6

      Pages: 304-307

    • NAID

      10016855093

    • Related Report
      2005 Annual Research Report
  • [Journal Article] ハイブリッドリポソーム単独投与による神経芽腫肝転移抑制効果2005

    • Author(s)
      根岸由香
    • Journal Title

      小児外科学会雑誌 41・7

      Pages: 930-937

    • Related Report
      2005 Annual Research Report
  • [Presentation] 蛍光脂質含有ハイブリッドリポソームのがん診断薬への応用2008

    • Author(s)
      永田 未歩
    • Organizer
      化学工学会第73年会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Diagnostic Application for Cancer Using Hybrid Liposomes Containing Fluorescent Labeling Lipids2008

    • Author(s)
      Nagata Miho, Osamu Tanoue, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 73rd Annual Meeting The Society of Chemical Engineers, Japan
    • Place of Presentation
      Shizuoka
    • Year and Date
      2008-03-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 細胞膜をターゲットとするハイブリッドリポソームの制がんメカニズム2008

    • Author(s)
      中田 小百合
    • Organizer
      化学工学会第73年会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] カルシウムイオン(Ca2+)のみによるin vitroでの制がん効果2008

    • Author(s)
      巽 一喜
    • Organizer
      化学工学会第73年会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes for Tumor Cells Leading to Apoptosis2008

    • Author(s)
      Sayuri Nakata, Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 73rd Annual Meeting The Society of Chemical Engineers, Japan
    • Place of Presentation
      Shizuoka
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effects of Calcium Ion(Ca^<2+>) without Drugs on the Growth of Tumor Cells in vitro2008

    • Author(s)
      Kazuki Tatsumi, Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 73rd Annual Meeting The Society of Chemical Engineers, Japan
    • Place of Presentation
      Shizuoka
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] カルシウムイオン(Ca^<2+>)のみによるin vitroでの制がん効果2008

    • Author(s)
      巽 一喜
    • Organizer
      化学工学会第73年会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes for Gastric Carcinoma Cells in Vitro2007

    • Author(s)
      Hideaki Ichihara
    • Organizer
      Frontiers in Gastrointestinal Cancer:Molecular Genetics, Inflammation, Early Detection and Therapy, KEYSTONE SYMPOSIA
    • Place of Presentation
      Beijing,China
    • Year and Date
      2007-10-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes for Gastric Carcinoma Cells in Vitro2007

    • Author(s)
      Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      Frontiers in Gastrointestinal Cancer : Molecular Genetics, Inflammation, Early Detection and Therapy, KEYSTONE SYMPOSIA
    • Place of Presentation
      Beijing, China
    • Year and Date
      2007-10-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes for Gastric Carcinoma Cells in Vitro2007

    • Author(s)
      Hideaki Ichihara
    • Organizer
      Frontiers in Gastrointestinal Cancer: Molecular Genetics, Inflammation, Early Detection and Therapy, KEYSTONE SYMPOSIA
    • Place of Presentation
      Beijing,China
    • Year and Date
      2007-10-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Chemotherapy with Hybrid Liposomes for Colon Tumor using Hepatic Metastasis Mice Model in vivo2007

    • Author(s)
      Hideaki Ichihara
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Kanagawa
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes without Drugs2007

    • Author(s)
      Yuji Komizu
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Kanagawa
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Hybrid Liposomes for Colon Tumor Using Hepatic Metastasis Mice Model in Vivo2007

    • Author(s)
      Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Kanagawa
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームの新しい化学療法2007

    • Author(s)
      古水 雄志
    • Organizer
      化学工学会第39回秋季大会
    • Place of Presentation
      北海道
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] 腎臓がんに対するカチオン性脂質含有複合脂質膜の制がん効果2007

    • Author(s)
      梅林 雅代
    • Organizer
      化学工学会第39回秋季大会
    • Place of Presentation
      北海道
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Novel Chemotherapy with Hybrid Liposomes2007

    • Author(s)
      Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The Society of Chemical Engineers, Japan, The 39th Autumn Meeting
    • Place of Presentation
      Hokkaido
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effects of Three-component Hybrid Liposomes Containing Cationic Lipids on the Growth of Human Renal Tumor Cells in Vitro2007

    • Author(s)
      Masayo Umebayashi, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The Society of Chemical Engineers, Japan, The 39th Autumn Meeting
    • Place of Presentation
      Hokkaido
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 極微小流量を制御できる組織形成装置を用いた肝がん細胞からの腫瘍組織形成と制がん剤開発への応用2007

    • Author(s)
      松下 琢
    • Organizer
      化学工学会第39回秋季大会
    • Place of Presentation
      北海道
    • Year and Date
      2007-09-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes for Tumor Cells Leading to Apoptosis2007

    • Author(s)
      Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      Annual General Member Meeting for the Scientific Research in Priority Areas Water and Biomolecules
    • Place of Presentation
      Nagano
    • Year and Date
      2007-08-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとする治療メカニズム2007

    • Author(s)
      松本 陽子
    • Organizer
      特定領域研究「水と生体分子」合同班会議
    • Place of Presentation
      長野
    • Year and Date
      2007-08-09
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームのアポトーシス誘導メカニズム2007

    • Author(s)
      古水 雄志
    • Organizer
      第16回日本アポトーシス研究会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2007-08-03
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Mechanism of Apoptosis in Tumor Cells with Hybrid Liposomes Targeting Cell Membranes2007

    • Author(s)
      Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 16th Annual Meeting of the Japanese Society for Apoptosis
    • Place of Presentation
      Chiba
    • Year and Date
      2007-08-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームの制がん効果2007

    • Author(s)
      上岡 龍一
    • Organizer
      第25回関西界面科学セミナー (特別講演)
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Immunostimulation Effects of Hybrid Liposomes on Human Peripheral Blood Mononuclear Cells2007

    • Author(s)
      Ryuichi Ueoka
    • Organizer
      The 25th Kansai Interface Science Seminar
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームの制がん効果2007

    • Author(s)
      上岡 龍一
    • Organizer
      第25回関西界面科学セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] マウス大腸がんに対するハイブリッドリポソームの肝転移抑制効果2007

    • Author(s)
      船本 幸太
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] ハイブリッドリポソームを用いる乳がん治療の前臨床試験2007

    • Author(s)
      下田 真也
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームの制がんメカニズム2007

    • Author(s)
      古水 雄志
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] ハイブリッドリポソームのヒト末梢血単核細胞に対する免疫賦活効果2007

    • Author(s)
      後藤 浩一
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Inhibitory Effect of Hybrid Liposomes on Hepatic Metastasis of Mouse Cacinoma in Vivo2007

    • Author(s)
      Kota Funamoto, Hideaki Ichihara, Ryuichi Ueoka
    • Organizer
      The 11th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Prechincal study of Breast Cancer Treatment by Hybrid Liposomes2007

    • Author(s)
      Shinya Shimoda, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 11th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mechanism of Anti-tumor with Hybrid Liposomes Targeting Cell Membrane2007

    • Author(s)
      Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 11th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Immunostimulation Effects of Hybrid Liposomes on Human Peripheral Blood Mononuclear Cells2007

    • Author(s)
      Koichi Goto, Yuji Komizu, Ryuichi Ueoka
    • Organizer
      The 11th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Osaka
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ハイブリッドリポソームの物性と制がんメカニズム2007

    • Author(s)
      上岡 龍一
    • Organizer
      第25回物性物理化学研究会 (特別講演)
    • Place of Presentation
      京都
    • Year and Date
      2007-06-22
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ハイブリッドリポソームの物性と制がんメカニズム2007

    • Author(s)
      上岡 龍一
    • Organizer
      第25回物性物理化学研究会
    • Place of Presentation
      京都
    • Year and Date
      2007-06-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] Chemotherapy with Hybrid Liposomes without Drugs2007

    • Author(s)
      Ryuichi Ueoka
    • Organizer
      1st International Symposium on Nanomedicine-from Basic to Applications-(ISNM2007) (招待講演)
    • Place of Presentation
      Aichi
    • Year and Date
      2007-04-22
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Hybrid Liposomes without Drugs(Invited Lecture)2007

    • Author(s)
      Ryuichi Ueoka
    • Organizer
      1st International Symposium on Nanomedicine -from Basic to Applications-(ISNM2007)
    • Place of Presentation
      Aichi
    • Year and Date
      2007-04-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Hybrid Liposomes without Drugs2007

    • Author(s)
      Ryuichi Ueoka
    • Organizer
      1st International Symposium on Nanomedicine-from Basic to Applications-(ISNM2007)
    • Place of Presentation
      愛知
    • Year and Date
      2007-04-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] Correlation of Physical Properties and Anticancer Mechanism of Hybrid Liposomes(Special Lecture)2007

    • Author(s)
      Ryuichi Ueoka
    • Organizer
      The 25th Annual Meeting of the Society of Physical Chemistry
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-01-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes for Colon Tumor Cells Leading to Apoptosis2006

    • Author(s)
      Yuji Komizu
    • Organizer
      The 4th Open Workshop for"Chemistry of Biological Processes Created by Water and Biomolecules"
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-12-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Drug-Free Hybrid Liposomes Composed of Dimyristoylphosphatidylcholine and Polyoxyethylenedodecyl Ether2006

    • Author(s)
      Hideaki Ichihara
    • Organizer
      The 4th Open Workshop for"Chemistry of Biological Processes Created by Water and Biomolecules"
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-12-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Drug-Free Hybrid Liposomes Composed of Dimyristoylphosphatidylchohne and Polyoxyethylenedodecyl Ether2006

    • Author(s)
      Hideaki Ichihara, Hideaki Nagami, Tetsuyuki Kiyokawa, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 4th Open Workshop for Chemistry of Biological Processes Created by Water and Biomolecules
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-12-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes for Colon Tumor Cells Leading to Apoptosis2006

    • Author(s)
      Yuji Komizu, Taku Matsushita, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 4th Open Workshop for Chemistry of Biological Processes Created by Water and Biomolecules
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-12-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Membrane Targeted Chemotherapy with Hybrid Liposomes for Colon Tumor Cells Leading to Apoptosis2006

    • Author(s)
      Yuji Komizu
    • Organizer
      UT Symposium on NanoBio Integration NANOBIO-TOKYO 2006
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-12-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 複合脂質膜の乳がんに対する制がん効果2006

    • Author(s)
      下田 真也
    • Organizer
      2006化学工学会鹿児島大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2006-11-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 腎臓がんに対するカチオン性脂質含有複合脂質膜の制がん効果2006

    • Author(s)
      梅林 雅代
    • Organizer
      2006化学工学会鹿児島大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2006-11-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes for Human Breast tumors in vitro and in vivo2006

    • Author(s)
      Shinya Shimoda, Hideaki Ichihara, Hideaki Nagami, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 2006 Kyushu Meeting of the Society of Chemical Engineers, Japan
    • Place of Presentation
      Kagoshima
    • Year and Date
      2006-11-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effects of Three-component Hybrid Liposomes Containing Cationic Lipids without Drugs on the Growth of Human Renal Tumor Cells in vitro2006

    • Author(s)
      Masayo Umebayashi, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 2006 Kyushu Meeting of the Society of Chemical Engineers, Japan
    • Place of Presentation
      Kagoshima
    • Year and Date
      2006-11-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy with Drug-Free Hybrid Liposomes Leading to Apoptosis2006

    • Author(s)
      Hideaki Ichihara
    • Organizer
      28th Symposium on Biomembrane-Drug Interaction
    • Place of Presentation
      Shizuoka
    • Year and Date
      2006-11-09
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 複合脂質膜の乳がんに対する制がん効果2006

    • Author(s)
      下田 真也
    • Organizer
      化学工学会第38回秋季大会
    • Place of Presentation
      福岡
    • Year and Date
      2006-09-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 担がん動物を用いた複合脂質膜の前臨床試験2006

    • Author(s)
      船本 幸太
    • Organizer
      化学工学会第38回秋季大会
    • Place of Presentation
      福岡
    • Year and Date
      2006-09-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effects of Hybrid Liposomes on the Growth of Human Breast Tumor Cells in vitro2006

    • Author(s)
      Shinya Shimoda, Hideaki Ichihara, Hideaki Nagami, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The Society of Chemical Engineers, Japan, The 38th Autumn Meeting
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-09-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chemotherapy' with Hybrid Liposomes for Colon Carcinoma without Drugs in Vivo2006

    • Author(s)
      Kota Funamoto, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The Society of Chemical Engineers, Japan, The 38th Autumn Meeting
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-09-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] がん細胞膜をターゲットとするハイブリッドリポソームのアポトーシス誘導機構2006

    • Author(s)
      古水 雄志
    • Organizer
      第10回がん分子標的治療研究会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] アポトーシス誘導複合脂質膜の乳がんに対する抑制効果2006

    • Author(s)
      市原 英明
    • Organizer
      第10回がん分子標的治療研究会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes toward Human Colon Adenocarcinoma Cells2006

    • Author(s)
      Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 10th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-01-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Induction of Apoptosis by Hybrid Liposomes for Human Breast tumor in vitro and in vivo2006

    • Author(s)
      Hideaki Ichihara, Hideaki Nagami, Tetsuyuki Kiyokawa, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 10th The Japanese Association for Molecular Target Therapy of Cancer
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-01-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 糖含有複合脂質膜の種々の腫瘍細胞に対する増殖抑制効果2005

    • Author(s)
      田中 芳浩
    • Organizer
      第42回化学関連支部合同九州大会
    • Place of Presentation
      福岡
    • Year and Date
      2005-07-02
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 複合脂質膜を用いた大腸がん治療に関する基礎研究2005

    • Author(s)
      船本 幸太
    • Organizer
      第42回化学関連支部合同九州大会
    • Place of Presentation
      福岡
    • Year and Date
      2005-07-02
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Fundamental Researches in Chemotherapy using Hybrid Liposomes for Colon Carcinoma2005

    • Author(s)
      Kota Funamoto, Yuji Komizu, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 42th Associated Chemical Meeting in Kyushu
    • Place of Presentation
      Fukuoka
    • Year and Date
      2005-07-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ハイブリッドリポソーム単独投与による神経芽腫の肝転移抑制効果2005

    • Author(s)
      永見 英明
    • Organizer
      第9回がん分子標的治療研究会総会
    • Place of Presentation
      京都
    • Year and Date
      2005-07-01
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effects of Three-component Hybrid Lioposomes Containing Sugar-sufactants without Drugs on the Growth of Tumor Cells in vitro2005

    • Author(s)
      Yoshihiro Tanaka, Koichi Goto, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 42th Associated Chemical Meeting
    • Place of Presentation
      Kyushu
    • Year and Date
      2005-07-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibitory Effect of Drug-Free Hybrid Liposomes on Metastasis of Mouse Neuroblastoma2005

    • Author(s)
      Hideaki Nagami, Joji Yoshizawa, Yoko Matsumoto, Ryuichi Ueoka
    • Organizer
      The 9th The japanese Association for Moolecular Target Therapy of Cancer
    • Year and Date
      2005-01-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A Novel Approach of Gentamicin Therapy for Duchenne Muscular Dystrophy Using Hybrid Liposomes and Establishment of a System to Identify the Patients Eligible for the Treatment2005

    • Author(s)
      Shigemi Kimura
    • Organizer
      The 8th Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      California,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A Novel Approach of Gentamichin Therapy for Duchenne Muscular Dystrophy Using Hybrid Liposomes and Establishment of a System to Identify the Patients Eligible for the Treatment2005

    • Author(s)
      Shigemi Kimura, Kaori Ito, Shro Ozasa, Hiroe Kewano, Makoto
    • Organizer
      The 8th Annual Meeting of the American Society of Gene Therapy
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] ナノメディシン-ナノテクの医療応用-(宇理須 恒雄編)2008

    • Author(s)
      上岡 龍一, 松本 陽子
    • Total Pages
      12
    • Publisher
      (株)オーム社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] ナノメディシン -ナノテクの医療応用-(宇理須 恒雄編)2008

    • Author(s)
      上岡 龍一, 松本 陽子
    • Total Pages
      12
    • Publisher
      (株)オーム社
    • Related Report
      2007 Annual Research Report
  • [Book] 診断・治療システムにおける化学工学「リボソームによるがん治療」2006

    • Author(s)
      市原 英明
    • Total Pages
      6
    • Publisher
      化学工学会バイオ部会
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 化学工学シンポジウムシリーズ2006

    • Author(s)
      市原 英明
    • Total Pages
      6
    • Publisher
      化学工業会
    • Related Report
      2006 Annual Research Report
  • [Book] BIONICS2006

    • Author(s)
      上岡 龍一
    • Total Pages
      3
    • Publisher
      オーム社
    • Related Report
      2006 Annual Research Report
  • [Book] 診断・治療システムにおける化学工学「リポソームによるがん治療」2006

    • Author(s)
      市原英明
    • Total Pages
      6
    • Publisher
      化学工学会バイオ部会
    • Related Report
      2005 Annual Research Report
  • [Book] 副作用のないがん治療への挑戦-ハイブリッドリポソーム, 生理活性物質-2005

    • Author(s)
      上岡 龍一
    • Total Pages
      8
    • Publisher
      化学工業社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 産官学連携の扉-生命科学をベースとした医療・健康への貢献-2005

    • Author(s)
      上岡 龍一
    • Total Pages
      2
    • Publisher
      化学工学会
    • Related Report
      2005 Annual Research Report
  • [Book] 特集 地方名産品の化学「焼酎と焼酎粕」2005

    • Author(s)
      上岡 龍一
    • Total Pages
      3
    • Publisher
      日本化学会
    • Related Report
      2005 Annual Research Report
  • [Book] 副作用のないがん治療への挑戦-ハイブリッドリポソーム・生理活性物質-2005

    • Author(s)
      上岡龍一
    • Total Pages
      8
    • Publisher
      化学工業社
    • Related Report
      2005 Annual Research Report
  • [Remarks] 「研究成果報告書概要(和文)」より

    • URL

      http://www.life.sojo-u.ac.jp/biomed/index.html

    • Related Report
      2007 Final Research Report Summary
  • [Remarks]

    • URL

      http://www.life.sojo-u.ac.jp/biomed/index.html

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2016-04-21  

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