Study of the mechanism mechanism of water homeostasis in the chicken
| Project/Area Number |
17380160
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Nagoya University |
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Principal Investigator |
SAITO Noboru Nagoya University, Graduate School of Bioagricutural Sciences, Associate Professor (40211924)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMADA Kiyoshi Nagoya University, Graduate School of Bioagricutural Sciences, Professor (40065579)
TSUKADA Akira Nagoya University, Graduate School of Bioagricutural Sciences, Assistant Professor (20343212)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥16,940,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2007: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2006: ¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2005: ¥8,900,000 (Direct Cost: ¥8,900,000)
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| Keywords | osmotic stimulation / chicken / anuaporin / vasotocin / gene expression / 遺伝子発現 / 浸透圧 / 浸透圧刺激 / 抗利尿ホルモン / アクアポリン / 転写調節因子 / 一酸化窒素 / 腎臓 / 水分再吸収 / 浸透圧調節 / 脳 |
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| Research Abstract |
For long time, it has been not clear about the osmoreceptor on the osmoregulation. Recently, aquaporin 4 (AQP4) has been a candidate as an osmoreceptor, but there are no clear evidence about that. We cloned chicken AQP4 cDNA and determined its sequence. We analyzed the gene expression of AQP4 in the chicken hypothalamus in related with osmostimulation. AQP4 gene expression in the chicken increased by hyperosmolality. Threrefore, these results suggest that AQP4 may involve osmoreceptor in the chicken. Since there are no observations about the increase of AQP4 gene expression by hyperosmolality in the mammals, such increase is specific thing in the chicken.
Comparing arginine vasotocin (AVT) gene expression between layer and broiler strain after water deprivation, both strains chick decreased body weights and increased plasma osmolality. On AVT gene expression, AVT gene expression increased hi layer but not in broiler. These results suggested that there was some different mechanism of osmoregulation between two strains.
It has been considered that neuropeptide Y (NPY) is a important role for feeding behavior. But, after water deprivation, NPY gene expression increased in the chicken. Therefore, these data suggest that NPY has a pivotal role on the water homeostasis in the chicken.
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] Profiles of mRNA expression of FOXL2, P450arom, DMRT1, AMH. P450c17, SF1, ERa and AR, in relation to gonadal sex differentiation in duck embryo.2008
Author(s)
Koba, N., Ohfuji, T., Ha, Y., Mizushima, S., Tsukada, A., Saito, N. Shimada, K.
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Journal Title
Journal of Poultry Science
Description
「研究成果報告書概要(和文)」より
Related Report
Peer Reviewed
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[Journal Article] Effects of aromatase inhibitor (Fadrozole)-induced sex-reversal on gonadal differentiation and mRNA expression of P450arom, AMH and ERa in quail embryos and growth in posthaching quail2008
Author(s)
Koba, N., Mori, M., Ha, Y., Mizushima, S., Tsukada, A., Saito, N., Shimada, K
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Journal Title
Journal of Poultry Science (accepted)
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Journal Article] Profiles of mRNA expression of FOXL2, P450arom, DMRT1, AMH. P450c17, SFI, ERa and AR, in relation to gonadal sex differentiation in duck embryo2008
Author(s)
Koba, N., Ohfuji, T., Ha, Y., Mizushima, S., Tsukada, A., Saito, N., Shimada, K
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Journal Title
Journal of Poultry Science (accepted)
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Journal Article] Developmental enhancement of intracytoplasmic sperm injection (ICSI)-generated quail embryos by phospholipase Cζ2008
Author(s)
Mizushima, S., Takagi, S., Ono, T., Atsumi, Y., Tsukada, A., Saito, N., Shimada, K
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Journal Title
Journal of Poultry Science (accepted)
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Journal Article] Fertilization and blastoderm development of quail oocytes after intracytoplasmic injection of chicken sperm bearing the W chromosome2007
Author(s)
Takagi, S., Ono, T., Tsukada, A., Atsumi, Y., Mizushima, S., Saito, N, Shimada, K
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Journal Title
Poultry Science 86
Pages: 937-943
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Z-chromosome specific primers for chicken-quail hybrid blastoderm2007
Author(s)
Takagi, S., Ono, T., Tsukada, A., Atsumi, Y., Mizushima, S., Saito, N, Shimada, K
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Journal Title
Journal of Poultry Science 44
Pages: 209-212
NAID
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Central administration of glucagons suppress food intake in chicks2007
Author(s)
Honda, K., Kamisoyama, H, Saito, N., Kurose, Y., Sugahara, K., Hasegawa, S
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Journal Title
Neuroscience Letters 416
Pages: 198-201
NAID
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Possible role of calcium on oocyte development after intrncytoplasmic sperm injection in quail (Coturnix japonica)2007
Author(s)
Mizushima, S., Takagi, S., Ono, T., Atsumi, Y., Tsukada, A., Saito, N., Shimada, K
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Journal Title
Journal of Experimental Zoology 307A
Pages: 647-653
Description
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[Journal Article] Identiftcation of Spermatogenic cells expressiong protamine mRNA in Japanese quail by RT-PCR2005
Author(s)
Upi Chairun, Nisa, Tsukada, A., Takagi, S., Yamamoto, I., Ha, Y., Hrabia, A., Saito, N., Shimada, K
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Journal Title
Journal of Poultry Science 42
Pages: 70-78
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] In vivo and in vitro screening of endocrine disrupting chemicals with estrogenic activity in Japanese quail2005
Author(s)
Shimada, K., Ha, Y., Tsukada, A., Saito, N., Maekawa, S., Nishizaka, M., Imagawa, M
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Journal Title
Avian and Poultry Biology Reviews 16
Pages: 19-27
NAID
Description
「研究成果報告書概要(欧文)」より
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