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STUDY OF VERY SMALL INJECTOR LINEAR ACCELERATOR WITH DIRECT PLASMA INJECTION SCHEME FOR HEAVYION CANCER THERAPY

Research Project

Project/Area Number 17390328
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionTokyo Institute of Technology

Principal Investigator

HATTORI Toshiyuki  Tokyo Institute of Technology, RESEARCH LABORATORY FOR NUCLEAR REACTORS, PROFESSOR (50134648)

Co-Investigator(Kenkyū-buntansha) HAYASHIZAKI Noriyosu  TOKYO INSTITUTE OF TECHNOLOGY, RESEARCH LABORATORY FOR NUCLEAR REACTORS, ASSISTANT PROFESSOR (50334537)
OKAMURA Masahiro  INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH, ENYO RADIATION LABORATORY, SENIOR RESEARCH SCIENTIST (80332245)
Project Period (FY) 2005 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥15,300,000 (Direct Cost: ¥15,300,000)
Fiscal Year 2006: ¥5,900,000 (Direct Cost: ¥5,900,000)
Fiscal Year 2005: ¥9,400,000 (Direct Cost: ¥9,400,000)
KeywordsLinear Accelerator / Particle Cancer Therapy / Direct Plasma Injection Scheme / Heavy Ion Source / Laser Ion Source / Proton Beam / Heavy Ion Beam / Alternating Phase Focusing Method / がん治療 / レーザーイオン源
Research Abstract

An accelerator system of particle cancer therapy was constructed by the accelerator technology of the 20th century. Therefore, the system is large and complex. We tried new accelerator technology of the 21st century for accelerator system of cancer therapy. These new technologies are Direct Plasma Injection Scheme (DPIS), Alternating Phase Focusing (APF) method of drift tube acceleration structure and 3-dimensional analysis of acceleration cavity.
A laser ion source was studied and developed for gas and solid target. We-succeeded product of high intensity ion by combining a cryogenic-cooler and a YAG laser. The results were contributed and published in international conference and international journal, respectively. We carried out the experiment with Direct Plasma Injection Scheme for APF Interdigital-H (IH) linear accelerator which was designed to accelerate ions with charge to mass ratio (q/A) of 1-1/3 from 40 keV/amu to 2 MeV/amu. We found that the improvement was necessary to realize large acceptance from the result of particle trajectory calculation. In order to decrease the cost of improvement, the liner accelerator cavity was modified as small as possible. In acceleration test in low energy injection, the APF-IH linear accelerator could not to get large acceptance by Direct Plasma Injection Scheme with laser ion source. Therefore, a hybrid single cavity linear accelerator was designed as new conception. A Radio Frequency Quadrupole (RFQ) type having good focusing performance in low energy region and a drift tube type having good acceleration performance in medium energy region were installed in a single cavity. Design study of the hybrid single cavity linear accelerator was contributed and published for International conference and International Journal, respectively.

Report

(3 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • Research Products

    (38 results)

All 2007 2006 2005

All Journal Article (24 results) (of which Peer Reviewed: 6 results) Presentation (14 results)

  • [Journal Article] Research of hybrid single cavity linac2007

    • Author(s)
      T.Ito, N.Hayashizaki, N.Matsunaga, T.Ishibashi, J.Tamura, L.Lu, T.Hattori
    • Journal Title

      Nuclear Instruments and Methods in P.R.Section B 261

      Pages: 17-20

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Ion generation from a solidified Ne target for a laser ion source2007

    • Author(s)
      J.Tamura, J.Okamura, T.Kanesue, S.Kondrashev
    • Journal Title

      Applied Physics Letters 91

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Research of hybrid single cavity linac2007

    • Author(s)
      T.Ito, N.Hayashizaki, N.Matsunaga, T.Ishibashi, J.Tamura, L.Lu, T.Hattori
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B 261

      Pages: 17-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Ion generation from a solidified Ne target for a laser ion source2007

    • Author(s)
      J.Tamura, J.Okamura, T.Kanesue, S. Kondrashev
    • Journal Title

      Applied Physics Letters 91

      Pages: 41504-173

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Research of hybrid single cavity linac2007

    • Author(s)
      T.Ito, N.Hayashizaki, N.Matsunaga, T.Ishibashi, J.tamura, T.Hattori
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B (In Press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] High current carbon beam production with direct plasma injection scheme2006

    • Author(s)
      M.Okamura, H.Kashiwagi, K.Sakakibara, R.A.Jameson, et. al.
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analysis of laser-produced heavy ions for direct plasma injection scheme2006

    • Author(s)
      K.Sakakibara, M, Okamura, S.Kondxashev, T.Hattori, et. al.
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Acceleration of high current fully stripped carbon ion beam by direct injection scheme2006

    • Author(s)
      H.Kashiwagi, M.Fukuda, M.Okamura, R.A.Jameson, et. al.
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] High current carbon beam production with direct plasma injection scheme2006

    • Author(s)
      M. Ohamura, H. Kashiwagi, K. Sakakibara, R. A. Jameson, K. Yamamoto, J. Takano, T. Hattori, N. Hayashizaki
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Analysis of laser-produced heavy ions for direct plasma injection scheme2006

    • Author(s)
      K. Sakakibara, M. Okamura, S. Kondrashev, T. Hattori, H. Kashiwagi, T. Kanesue
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Acceleration of high current fully stripped carbon ion beam by direct injection scheme2006

    • Author(s)
      H. Kashiwagi, M. Fukuda, M. Okamura, R. A. Jameson, T. Hattori, N. Hayashizaki, K. Sakakibara, J. Takano, K. Yamamoto, Y. Iwata, T. Fujimoto
    • Journal Title

      Review of Scientific Instruments 77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] PET. Beam Accelerator System for Future Cancer Therapy2006

    • Author(s)
      T.hattori, N.Hayashizaki, S.Ueda, T.Ito, et al.
    • Journal Title

      Proceedings of the 8th symposium on accelerator and related technology for application 8

      Pages: 11-14

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Electric Field Simulation in Hybrid Single Cavity Linac2006

    • Author(s)
      T.Ito, N.Hayashizaki, N.Matsunaga, T.Ishibashi, J.tamura, T.Hattori
    • Journal Title

      Proceedings of the 9th symposium on accelerator and related technology for application 8

      Pages: 15-16

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Next Generation PET Beam Accelerator System for Cancer Therapy2006

    • Author(s)
      T.hattori, N.Hayashizaki, S.Ueda, T.Ito, et al.
    • Journal Title

      Proceedings of the 3rd Annual Meetion of Particle Accelerator Society of Japan 3

      Pages: 218-220

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Design of Hybrid Single Cavity Linac2006

    • Author(s)
      T.Ito, N.Hayashizaki, N.Matsunaga, T.Ishibashi, J.tamura, T.Hattori
    • Journal Title

      Proceedings of the 4rd Annual Meetion of Particle Accelerator Society of Japan 3

      Pages: 807-808

    • NAID

      130007031941

    • Related Report
      2006 Annual Research Report
  • [Journal Article] High current carbon beam production with direct plama injection scheme2006

    • Author(s)
      M.Okamura, H.Kashiwagi, K.Sakakibara, et al.
    • Journal Title

      Review of Scientific Instruments 77

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Experimental results of DPIS with new RFQ2005

    • Author(s)
      M.Okamura, R.A.Jameson, H.Kashiwagi, T.Hattori, et. al.
    • Journal Title

      Radiation Effects & Defects in Solids 160

      Pages: 445-449

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Experimental results of DPIS with new RFQ2005

    • Author(s)
      M. Okamura, R. A. Jameson, H. Kashiwagi, T. Hattori, N. Hayashizaki, K. Sakakibara, K. Yamamoto, T. Kanesue
    • Journal Title

      Radiation Effects & Defects in Solids 160

      Pages: 445-449

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Proof examination of alternating phase focusing2005

    • Author(s)
      K.Yamamoto, T.Hattori, N.Hayashizaki, et al.
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B 240

      Pages: 44-47

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Experimental results of DPIS with new RFQ2005

    • Author(s)
      M.Okamura, R.A.Jameson, H.Kashiwagi, et al.
    • Journal Title

      Radiation Effects & Defects in Solids 160

      Pages: 445-449

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 60 mA carbon beam acceleration with DPIS2005

    • Author(s)
      M.Okamura, R.A.Jameson, J.Takano, et al.
    • Journal Title

      Proc.of 2005 Particle Accelerator Conference

      Pages: 2206-2208

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Properties of laser-produced highly charged heavy ions for direct injection scheme2005

    • Author(s)
      K.Sakakibara, T.Hattori, N.Hayashizaki, et al.
    • Journal Title

      Proc.of 2005 Particle Accelerator Conference

      Pages: 1976-1978

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Acceleration of high current and highly charged carbon beam using direct injection scheme2005

    • Author(s)
      H.Kashiwagi, M.Okamura, R.A.Jameson, T.Hattori, et al.
    • Journal Title

      Proc.of the 2nd Annual Meeting of Particle Accelerator Society of Japanand the 30th Linear Accelerator Meeting in Japan 2

      Pages: 182-184

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Acceleration test of a high energy-gain IH-linac2005

    • Author(s)
      K.Yamamoto, T.Hattori, M.Okamura, N.Hayashizaki, et al.
    • Journal Title

      Proc.of the 7th symposium on accelerator and related technology for application 7

      Pages: 73-76

    • Related Report
      2005 Annual Research Report
  • [Presentation] Use of solidified gas target to laser ion source2007

    • Author(s)
      J.Tamura, M.Okamura, T.Kanesue
    • Organizer
      Particle Accelerator Conference 2007
    • Place of Presentation
      Albuquerque,NM,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Use of solidified gas target to laser ion source2007

    • Author(s)
      J. Tamura, M. Okamura, T. Kanesue
    • Organizer
      Particle Accelerator Conference 2007
    • Place of Presentation
      Albuquerque, NM, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Laser-based heavy ion production2006

    • Author(s)
      M.Okamura
    • Organizer
      Linear Accelerator Conference 2007
    • Place of Presentation
      Knoxville,TN,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Application of DPIS to IH linac2006

    • Author(s)
      J.Tamura, T.Hattori, N.Hayashizaki, T.Ito, T, et. al.
    • Organizer
      European Particle Accelerator Conference 2006
    • Place of Presentation
      Edinburgh,UK
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Generation of highly charged ions using Nd-glass laser2006

    • Author(s)
      S.Kondrashev, T.Kanesue, M.Okamura, K.Sakakibara
    • Organizer
      European Particle Accelerator Conference 2006
    • Place of Presentation
      Edinburgh,UK
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Next generation pet beam accelerator system for cancer therapy2006

    • Author(s)
      T.Hattori, N.Hayashizaki, J.Tamura, S.Ueda, T.Ito, et. al.
    • Organizer
      The 3rd Annual Meeting of Particle Accelerator Society of Japan and the 31st Linear Accelerator Meeting in Japan
    • Place of Presentation
      Sendai,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Laser-based heavy ion production2006

    • Author(s)
      M. Okamura
    • Organizer
      Linear Accelerator Conference 2006
    • Place of Presentation
      Knoxville, TN, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Application of DPIS to IH linac2006

    • Author(s)
      J. Tamura, T. Hattori, N. Hayashizaki, T. Ito, T, Ishibashi, J. Hasegawa, M. Okamura, S. Kondrashev
    • Organizer
      European Particle Accelerator Conference 2006
    • Place of Presentation
      Edinburgh, UK
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Generation of highly charged ions using Nd-glass laser2006

    • Author(s)
      S. Kondrashev, T. Kanesue, M. Okamura, K. Sakakibara
    • Organizer
      European Particle Accelerator Conference 2006
    • Place of Presentation
      Edinburgh, UK
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Next generation pet beam accelerator system for cancer therapy2006

    • Author(s)
      J. Tamura, S. Ueda, T. Ito, J. Takano, T. Ishibashi, N. Matsunaga, M.Ito, A. Kiyomiya, Lu Liang, M. Okamura, E. Osvath, D. Biro. T, Hattori, N. Hayashizaki
    • Organizer
      The 3rd Annual Meeting of Particle Accelerator Society of Japan and the 31st Linear Accelerator Meeting in Japan
    • Place of Presentation
      Sendai, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] The comparison of a new beam-tracking code to the acceleration test2006

    • Author(s)
      K.Yamamoto, M. Okamura, T. Hattori, S.Yamada
    • Organizer
      Particle Accelerator Conference 2005
    • Place of Presentation
      Knoxville, TN, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] The comparison of a new beamtracking code to the acceleration test2005

    • Author(s)
      K.Yamamoto, M.Okamura, T.Hattori, S.Yamada
    • Organizer
      Particle Accelerator Conference 2005
    • Place of Presentation
      Knoxville,TN,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Properties of laserproduced highly charged heavy ions for direct injection scheme2005

    • Author(s)
      K.Sakakibara, T.Hattori, N.Hayashizaki, T.Ito, et. al.
    • Organizer
      Particle Accelerator Conference 2005
    • Place of Presentation
      Knoxville,TN,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Presentation] Properties of laser-produced highly charged heavy ions for direct injection scheme2005

    • Author(s)
      K. Sakakibara, T. Hattori, N. Hayashizaki, T. Ito, H. Kashiwagi, M. Okamura
    • Organizer
      Particle Accelerator Conference 2005
    • Place of Presentation
      Knoxville, TN, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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