| Project/Area Number |
17390338
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Teikyo University |
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Principal Investigator |
FURUI Shigeru Teikyo University School of Medicine, Department of Radiology, Professor, 医学部, 教授 (40114631)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Hironobu Osaka University Graduate School of Medicine, Department of Radiology, Professor, 医学部, 教授 (00116071)
ISHIGUCHI Tsuneo Aichi Medical University, Department of Radiology, Professor, 医学部, 教授 (70115525)
YAMAGUCHI Ichiro National Institute of Public Health, Senior Research Officer, 生活環境部, 主任研究官 (50311395)
ISSHIKI Takaaki Teikyo University School of Medicine, Department of Medicine, Professor, 医学部, 教授 (60150273)
SUZUKI Shigeru Teikyo University School of Medicine, Department of Radiology, Lecturer, 医学部, 助手 (60317691)
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| Project Period (FY) |
2005 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥11,000,000 (Direct Cost: ¥11,000,000)
Fiscal Year 2006: ¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2005: ¥7,900,000 (Direct Cost: ¥7,900,000)
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| Keywords | Radiation / Exposure / Dosage / Interventional Radiology |
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| Research Abstract |
We developed two types of radiosensitive indicators (high dose type, low dose type) to estimate patients' entrance skin dose (ESD) during interventional radiology procedures. We assessed the relationship between color difference of the indicators and absorbed doses. With low dose type, the response was almost linear with the natural logarithm of the dose from 0.3 to 6 Gy. With high dose type, the response was almost linear with the natural logarithm of the dose from 3 to 15 Gy. Based on this relationship, we can calculate the absorbed dose from the color of indicator.
Using these indicators, we assessed the patients' ESD during 3 types of interventional procedures. This study included consecutive 72 patients who underwent percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in the 6 institutions, 104 patients who underwent catheter ablation for arrhythmia in the 3 institutions, 103 patients who underwent neurointerventional procedures in the 6 institutions. They wore jackets with 100 radiosensitive indicators adhered to the back during the PCI and ablation procedures, or caps with 44 indicators during the interventional procedures. The maximum ESD for each patient was 3.2 ± 2.1 Gy (range : 0.5 - 10.2 Gy, median : 2.7 Gy) for PCI, 0.5 ± 0.5 Gy (range : 0.0 - 2.7 Gy, median : 0.5 Gy) for ablation, and 1.9 ± 1.1 Gy (range : 0.4 - 5.6 Gy, median : 1.5 Gy) for neurointervention. Radiation skin injuries were observed in 2 patients of PCI, and 6 of neurointervention.
In many cases of PCI for CTO and some cases of neurointervention, the maximum ESDs exceed the thresholds for radiation skin injuries. Therefore, the patients' ESDs should be estimated to reduce the doses in these interventional procedures.
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