| Project/Area Number |
17390513
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TAKAHASHI Hidekazu Tokyo Medical and Dental University, Graduate School, Associate Professor (90175430)
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| Co-Investigator(Kenkyū-buntansha) |
MIURA Masahiko Tokyo Medical and Dental University, Graduate School, Associate Professor (10272600)
YOSHIKAWA Takako Tokyo Medical and Dental University, Graduate School, Research Associate (00182733)
TANAKA Yoshihiro Tokyo Medical and Dental University, Graduate School, Research Associate (20361719)
YOSHIKAWA Takatomo Tokyo Medical and Dental University, Graduate School, Research Associate (60323698)
IWASAKI Naohiko Tokyo Medical and Dental University, Faculty of Dentistry, Engineer (20242216)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥16,630,000 (Direct Cost: ¥15,700,000、Indirect Cost: ¥930,000)
Fiscal Year 2007: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2006: ¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2005: ¥9,700,000 (Direct Cost: ¥9,700,000)
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| Keywords | gamma-ray irradiation / irradiation therapy / dentin / tensile strength / bonding strength / SDS-PAGE / sealing ability of root canal / 歯質 / 放射線照射 / ガンマ線 / 被削性 / 保存液 |
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| Research Abstract |
The purpose of this study was to evaluate the effects of gamma-ray irradiation on physical properties of dentin. Bovine teeth were mainly used because of their homogenous properties.
The effects of 60 Gy (for irradiation therapy), 3 kGy (for general sterilization) and 30 kGy (sterilization for irradio-resistant gems) irradiation on tensile strength, machinability, adhesion, and root canal treatment were examined. The tensile strength and machinability of dentin with and without 60 Gy irradiation were not significantly different immediately after irradiation. The tensile strength and machinability of dentin stored in chloramin T and Thimol for 1 year after 60-Gy irradiation were not statistically different from those without irradiation. However, the tensile strength after 30 kGy irradiation was significantly smaller than that after 60 Gy or 3 kGy irradiation. SDS page analysis showed that the protein band from collagen could not be detected after 30 kGy irradiated dentin. Bonding strength of composite resin to 60-Gy irradiated dentin did not changed. Root canal sealing did not change after 60 Gy irradiation, but decreased after 3 kGy and 30 kGy irradiation. These results suggested that the gamma-ray irradiation at a dose for irradiation therapy did not obviously affect the physical properties of dentin, but that at a dose for sterilization affect the physical properties of dentin.
These findings were presented at domestic and international meeting such as IADR meeting and will be submitted to a journal.
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