| Project/Area Number |
17500326
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Medical systems
|
|---|
| Research Institution | Chiba University |
|---|
Principal Investigator |
HACHIYA Hiroyuki Chiba University, Research Center for frontier Medical Engineering, Professor, フロンティアメディカル工学研究開発センター, 教授 (90156349)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YAMAGUCHI Tadashi Chiba University, Faculty of Engineering, Research Associate, 工学部, 助手 (40334172)
|
|---|
| Project Period (FY) |
2005 – 2006
|
| Project Status |
Completed (Fiscal Year 2006)
|
| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2006: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2005: ¥2,200,000 (Direct Cost: ¥2,200,000)
|
|---|
| Keywords | Tissue Characterization / Quantitative diagnosis / Ultrasonic diagnosis / Echo filter / Probability density function / 超音波 / 医用画像 / 肝硬変 |
|---|
| Research Abstract |
In the clinical diagnosis using ultrasonic diagnostic equipment, it is difficult to understand the tissue structure by using only two dimensional plane information of ultrasonic B-mode image. In this research, we tried to understanding the relationship between the tissue change that caused by some disease such as fibrosis and the characteristics change (of echo signal for ultrasonic images).
The three dimensional echo filter was disigned to improve the accuracy when data is collected with ultrasonic diagnostic equipment. The resolution of the ultrasonic beam which was irradiated to human body is differs respectively in depth, the azimuth, and the direction of the elevation. Then, the measurement accuracy for every has been improved by deciding the parameter of the filter based on resolution in the direction of three dimensions.
Moreover, we proposed signal analyzing methods for quantitative diagnosis. Our methods paid attention to the relation between the scatter density and the characteristics of echo signal in the living human body. Quantifying the feature of a different element in an inhomogeneous medium (diseased tissue) became possible by combining some analytical methods.
In addition, the system to measure the acoustic characteristic of the biological tissue high-speed and in a high density was restructured. As a result of measurement of eight liver specimens, the measurement speed and the range that can be measured quadrupled compared with the previous system. As a result, the error margin because of the change in the measurement environment decreased, and a highly accurate measurement became possible.
|
