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Investigation of modulation of skin vasodilator function by exercise training in a hot environment

Research Project

Project/Area Number 17500453
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionUniversity of Occupational and Environmental Health, Japan

Principal Investigator

FUMIO Yamazaki  University of Occupational and Environmental Health, Japan, School of Health Sciences, Assistant Professor (80269050)

Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2006: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2005: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsSkin blood flow / Sweating / Heat acclimation / Exercise training / Core temperature / 発汗調節 / トレーニング / 皮膚血流調節 / 体温調節 / イオン導入法 / 血管内皮機能 / 一酸化窒素
Research Abstract

Exercise training in a hot environment modulates the controlling system of skin blood flow and sweating, important thermoregulatory functions, in humans. Most of the findings regarding the modulation of skin vasomotor control by exercise training (or heat acclimation) are obtained from studies of nonglabrous (hairy) skin, usually forearm skin, but information about the influence of heat acclimation on glabrous (nonhairy) skin such as the palm is restricted. In this project, we examined the vasomotor responses in the glabrous and nonglabrous skin during whole body heating before and after a 6-day exercise-heat acclimation program. We also examined changes in the control of sweating by heat acclimation by using frequency of sweat expulsion, an index of central sudomotor activity. Eight healthy young volunteers underwent a six-day heat acclimation program [a total of 80-min exercise at 50% peak rate of oxygen consumption in the heat (36℃)]. In the days before and after the heat acclimation program, we examined the local sweating rate at the chest and forearm, frequency of sweat expulsion, and esophageal temperature during whole body heating using a water-perfused suit. As a result, short-term heat acclimation did not change the vascular response in glabrous skin to a raised core temperature but decreased the temperature threshold for vasodilation in nonglabrous skin. It was also suggested that short-term heat acclimation modulates central sudomotor mechanisms, decreasing the temperature threshold for sweating but does not change in the peripheral mechanism for sweating.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (14 results)

All 2008 2007 2006

All Journal Article (9 results) (of which Peer Reviewed: 6 results) Presentation (5 results)

  • [Journal Article] Short-term heat acclimation does not alter the vasodilator response in glabrous skin during heat stress2008

    • Author(s)
      Fumio Yamazaki
    • Journal Title

      Japanese Journal of Physical Fitness and Sports Medicine 57巻

      Pages: 169-174

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Short-term heat acclimation does not alter the vasodilator response in glabrous skin during heat stress2008

    • Author(s)
      Fumio Yamazaki
    • Journal Title

      Japanese Journal of Physical Fitness and Sports Medicine 57

      Pages: 169-174

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Short-term heat acclimation does not alter the vasodilatorresonse in glabrous skin during heat stress2008

    • Author(s)
      Fumio.Yamazaki
    • Journal Title

      Japanese Journal of Physical Fitness and SportsMedicine 57巻

      Pages: 169-174

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hyperoxia attenuates endothelial-mediated vasodilation in the human skin2007

    • Author(s)
      Fumio Yamazaki
    • Journal Title

      The Journal of Physiological Sciences 57巻

      Pages: 81-84

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 汗の拍出頻度よりみた短期暑熱順化による発汗機能の変化2007

    • Author(s)
      山崎 文夫, 生田 智也, 曽根 涼子
    • Journal Title

      産業医科大学雑誌 29巻

      Pages: 431-438

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Hyperoxia attenuates endothelial-mediated vasodilotion in the human skin2007

    • Author(s)
      Fumio Yamazaki
    • Journal Title

      The Journal of Physiological Sciences 57

      Pages: 81-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Modulation of central sudomotor control by short-term heat acclimation as evidenced by frequency of sweat expulsions2007

    • Author(s)
      Fumio Yamazaki, Tomoya Ikuta, Ryoko Sone
    • Journal Title

      Journal of UOEH 29

      Pages: 431-438

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Hyperoxia attenuates endothelial-mediated vasodilationin the human skin2007

    • Author(s)
      Fumio Yamazaki
    • Journal Title

      The Journal of Physiological Sciences 57巻

      Pages: 81-84

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 汗の拍出頻度よりみた短期暑熱順化による発汗機能の変化2007

    • Author(s)
      山崎 文夫、生田 智也、曽根 涼子
    • Journal Title

      塵業医科大学雑誌 29巻

      Pages: 431-438

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Roles of nitric oxide and prostaglandins in the hyperoxic vasoconstriction in human skin2007

    • Author(s)
      Fumio Yamazaki, Kazuo Takahara, Ryoko Sone, John M.Johnson
    • Organizer
      Experimental Biology 2007
    • Place of Presentation
      Washington DC,U.S.A.
    • Year and Date
      2007-04-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of nitric oxide and prostaglandins in the hyperoxic vosoconstriction in human skin2007

    • Author(s)
      Fumio Yamazaki, Kqzuo Takahara, Ryoko Sone, John M. Johnson
    • Organizer
      Experimental Biology 2007
    • Place of Presentation
      Washington DC, U.S.A
    • Year and Date
      2007-04-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of nitric oxide and prostaglandins in the hyperoxic vasoconstriction in human skin2007

    • Author(s)
      Fumio Yamazaki、Kazuo Takahara、Ryoko Sone、John M.Johnson
    • Organizer
      Experimental Bioldgy2007
    • Place of Presentation
      Washington DC、U.S.A
    • Year and Date
      2007-04-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] Influence of hyperoxia on skin vascular responses to acethylcholine and sodium nitroprusside2006

    • Author(s)
      Fumio Yamazaki, Kazuo Takahara, John M.Johnson
    • Organizer
      2nd International Meeting on Physiology and Pharmacology of Temperature Regulation
    • Place of Presentation
      Phoenix,U.S.A.
    • Year and Date
      2006-03-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] lnfluence of hyperoxia on skin vascular responses to ace acethylcholine and sodium nitroprusside2006

    • Author(s)
      Fumio Yamazaki, Kqzuo Takahar, John M. Johnson
    • Organizer
      2nd lnternational Meeting on physiology and Pharmacology of Temperoture Regulation
    • Place of Presentation
      Phoenix, U.S.A
    • Year and Date
      2006-03-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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