| Project/Area Number |
17560064
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
SAKUMA Atsushi Tokyo University of Agriculture and Technology, Institute of Symbiotic Science and Technology, Associate Professor (60274180)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,650,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | Biological Tissue / Viscoelasticity / Medical Examination. / Medical Engineering / Simulation / FEM / Deformation Analysis / Control |
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| Research Abstract |
Biological tissue consists of cells and their deformation affects to various mechanics in medical and biotechnological field.
A bi-axial tensile testing machine is developed to control the amount of tensile displacement by using servo motor in the first step of this research. Then the testing machine is used under birefringent microscope for the observation of strain distribution in the tissue. The results of the testing indicate that the inside of cells is filled by structural materials and the structure causes the difficulties in the analysis of the tissue deformation.
The complicated deformation of the tissue is also observed in macroscopic testing systems. Fundamental tensile testing is adopted to evaluate the viscoelastic behavior of the tissue which is affected by the solid-liquid coupled structure. The constitutive model of 3-element solid is used in the evaluation and it indicates that the tissue have high nonlinearity even if industrial materials like metal have low one.
The nonlinearity caused by the cellar structure is also observed in other macroscopic testings. Uniaxial and biaxial testings are adopted to the observation, and the representation idea of the nonlinearity is shown by using transformation theory.
And then the adaptive distribution techniques of FEM are discussed for the research objective. The adaptation of FE domain is realized by using the equation of load balance. Continuous analysis between different materials is realized by modification of solving procedure.
As the conclusion of this research, some study on nonlinearity of the cellar structure and viscous deformation is evaluated with the development of testing machines. The adaptation method of distributed FEM is also discussed for the research objectives.
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