| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Koichi Niigata University, Institution of Medicine and Dentistry, Assistant, 医歯学系, 助手 (70296317)
TANABE Yuji Niigata University, Institution of Science and Technology, Professor, 自然科学系, 教授 (60143020)
OMORI Go Niigata University, Center for Transdisciplinary Research, Professor, 超域研究機構, 教授 (70283009)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2005: ¥2,700,000 (Direct Cost: ¥2,700,000)
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| Research Abstract |
Determination of the distribution and magnitude of joint contact area is necessary step toward understanding the effects of loading on articular cartilage. Traditionally, such data have been obtained from cadaver specimens. Recently, Magnetic Resonance Imaging (MRI) was shown to be valid method of quantifying patellofemoral joint contact area indicating the potential for in vivo assessment. In this study, at first, the closed type of MRI was used to quantify in vivo patellofemoral joint contact area and contact distribution. Five males and five females participated in this study. All subjects were free of knee pain and had no history of knee surgery. Cartilage-enhanced MR images were obtained at 0°, 30°, 60° and 90° knee flexion under knee loaded conditions. Male subjects displayed patellofemoral joint contact areas of 86.1±16.7,148.7±78.6,210.7±81.1 and 362.3±76.7mm^2 at 0°, 30°, 60° and 90° knee flexion, respectively. Female subjects' contact areas were 1.4±37.5,124.6±72.1,163.4±78.2 and 247.5±27.1 mm^2 at each knee flexion, respectively, and significantly smaller than contact areas of males at 90° (p<0.05). When normalized by patellar joint surface areas, normalized contact areas were not different between genders. Then, we also analyzed the region and contact area of taloctual joint with MRI which can observe contact situation of joint in vivo. We proved change of contact region intended for normal ankle in plantar and dorsal flexion. From plantar 10° by maximum dorsal flexion, the contact area was stable state, more than 35% of taloctual joint surface. As the flexion angle became deep in the palatal direction from normal flexion, contact area became narrow and decreased to 1/4 of joint surface in the maximum plantar flexion.
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