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Immobilization of Photoelectric Dye on the Polyethylene Film Surface -A Prototype Retinal Prosthesis-

Research Project

Project/Area Number 17560605
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Composite materials/Physical properties
Research InstitutionOkayama University

Principal Investigator

UCHIDA Tetsuya  Graduate School of Natural Science and Technology, Assistant, 大学院自然科学研究科, 助手 (90284083)

Co-Investigator(Kenkyū-buntansha) SHIMAMURA Kaoru  Graduate School of Natural Science and Technology, Professor, 大学院自然科学研究科, 教授 (80013506)
MATSUO Toshihiko  Graduate School of Medicine and Dentistry, Associate Professor, 大学院医歯薬学総合研究科, 助教授 (90211565)
Project Period (FY) 2005 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2005: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsPhotoelectric Dye / Retinal Prosthesis / Polyethylene / Film / Surface
Research Abstract

Polyethylene (PE) film was treated with fuming nitric acid at 80°C for 20 min, resulting in introduction of COOH moieties on the film surface. The COOH's were reacted with ethylenediamine, whose amino groups were used for linking with (2-[4-(dibutylamino)phenyl]ethenyl)-3-carboxy-methylbenzo-thiazolium, photoelectric dye (NK-5962), which absorbs visible light and converts the photon energy to electric potentials. The dye molecules were immobilized on the PE film surface and they were able to stimulate chick retinal tissues on incidence of visible light. These facts hopefully lead to development of an artificial retinal prosthesis.

Report

(3 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • Research Products

    (6 results)

All 2006 2005

All Journal Article (6 results)

  • [Journal Article] The Response and Adhesiveness of Chick Embryonic Retinal Neurons to Photoelectric Dye-Coupled Polyethylene Films as Prototypes of Retinal Prostheses.2006

    • Author(s)
      Akihito Uji, Toshihiko Matsuo, Tetsuya Uchida, Kaoru Shimamura, Hiroshi Ohtsuki
    • Journal Title

      Artificial Organs 30(9)

      Pages: 695-703

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mixed Neuronal and Glial Colony Formation on the Surface of Photoelectric Dye-Coupled Polyethylene (Okayama University Type Retinal Prosthesis)2006

    • Author(s)
      A.Uji, T.Matsuo, T.Uchida, K.Shimamura, H.Ohtsuki
    • Journal Title

      Invest. Ophthalmol. Vis. Sci. 47

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The Response and Adhesiveness of Chick Embryonic Retinal Neurons to Photoelectric Dye-Coupled Polyethylene films as Prototypes of Retinal Prostheses.2006

    • Author(s)
      Akihito Uji, Toshihiko Matsuo, Tetsuya Uchida, Kaoru Shimamura, Hiroshi Ohtsuki
    • Journal Title

      Artificial Organs 30(9)

      Pages: 695-703

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Mixed Neuronal and Glial Colony Formation on the Surface of Photoelectric Dye-Coupled Polyethylene(Okayama University Type Retinal Prosthesis)2006

    • Author(s)
      A.Uji, T.Matsuo, T.Uchida, K.Shimamura, H.Ohtsuki
    • Journal Title

      Invest. Ophthalmol. Vis. Sci. 47

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Immobilization of photoelectric dye on the polyethylene film surface.2005

    • Author(s)
      Tetsuya Uchida, Sanae Ishimaru, Kaoru Shimamura, Akihito Uji, Toshihiko Matsuo, Hiroshi Ohtsuki
    • Journal Title

      Memoirs of the Faculty of Engineering, Okayama University 39

      Pages: 16-20

    • NAID

      120002308066

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Photoelectric Dye-coupled Polyethylene Film as a Prototype of Retinal Prostheses2005

    • Author(s)
      Akihito Uji, Toshihiko Matsuo, Sanae Ishimaru, Akiko Kajiura, Kaoru Shimamura, Hiroshi Ohtsuki, Yasufumi Dan-oh, Sadaharu Suga
    • Journal Title

      Artificial Organs 29

      Pages: 53-57

    • Related Report
      2005 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2016-04-21  

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