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Immunoglobulin genes of teleosts : Discovery of new immunoglobulin class.

Research Project

Project/Area Number 17580164
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General fisheries
Research InstitutionUniversity of Miyazaki

Principal Investigator

SAKAI Masahiro  University of Miyazaki, Faculty of Agriculture, Professor, 農学部, 教授 (20178536)

Project Period (FY) 2005 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2005: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywordsimmunoglobulin / carp / fugu / IgT / teleost / 魚類 / コイ / 硬骨魚
Research Abstract

Characterization of teleost IGH loci is near completion. Although. the basic structure of the IGH loci is conserved, species specific variations exist across teleosts. In general, teleosts have three major Ig heavy chain isotypes. Analysis of IGH genomic region suggests no additional discovery of IgH genes will be forthcoming, at least not from downstream region of d gene (Bengten et al. 2006). The novel Ig isotype along with IgM and IgD will be good tools to study the immune responses and biology of 3-cells in fish.

Report

(3 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • Research Products

    (7 results)

All 2007 2006 2005

All Journal Article (5 results) Book (2 results)

  • [Journal Article] Discovery of a novel immunoglobulin heavy chain gene chimera from common carp (Cyprinus carpio L.).2006

    • Author(s)
      Savan, R., Aman, A., Nakaio, M., Watanuki, H., Sakai, M.
    • Journal Title

      Immunogenetics 57

      Pages: 456-463

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Discovery of a new class immunoglobulin heavy chain from Japanese pufferfish : An unusual pattern seen in the genomic organization of the IgH locus.2005

    • Author(s)
      Savan, R., Aman, A., Sato, K., Yamaguchi, R., Sakai, M.
    • Journal Title

      European Journal of Immunology 35

      Pages: 3320-3331

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Discovery of a novel immunoglobulin heavy chain gene chimera from common carp (Cyprinus carpio L. ).2005

    • Author(s)
      Savan, R., Aman, A., Nakaio, M, Watanuki, H., Sakai, M.
    • Journal Title

      Immunogenetics 57

      Pages: 458-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Discovery of a novel immunoglobulin heavy chain gene chimera from common carp (Cyprinus carpio)2005

    • Author(s)
      Savan, R., Aman, A., Nakao, M., Watanuki, H., Sakai, M.
    • Journal Title

      Immunogenetics 57

      Pages: 458-463

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Discovery of a new class of immunoglobulin heavy chain from fugu2005

    • Author(s)
      Savan R., Aman, A., Sato, K., Yamaguchi, R.Sakai, M.
    • Journal Title

      European Journal of Immunology 35(11)

      Pages: 3320-3330

    • Related Report
      2005 Annual Research Report
  • [Book] Fish Defense Immunoglobulin genes of teleosts : Discovery of new immunoglobulin class.2007

    • Author(s)
      Savan, R., Sakai, M.
    • Publisher
      Elsever(未定(印刷中))
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] Fish Defense : Immunoglobulin genes of teleosts : Discovery of new immunoglobulin class22007

    • Author(s)
      Savan, R., Sakai, M.
    • Publisher
      Elsevier(未定 )
    • Related Report
      2006 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2016-04-21  

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