| Project/Area Number |
17580176
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fisheries chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
OKINO Tatsufumi Hokkaido Univ., Fac.Env.Earth Sci., Asso.Prof., 大学院地球環境科学研究院, 助教授 (30280910)
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| Co-Investigator(Kenkyū-buntansha) |
YAZAKI Ikuko Tokyo Metro.Univ., Fac.Urban Lib. Arts, Researcher, 都市教養学部理工学系, 客員研究員 (50381447)
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| Project Period (FY) |
2005 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2005: ¥2,400,000 (Direct Cost: ¥2,400,000)
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| Keywords | sea urchin / sea cucumber / holothurian / Ulvella / dopamine / phenylalanine / metamornhosis / inducer / Ulvella / ヒスタミン / 天然珪藻 |
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| Research Abstract |
To understand chemical inducers of echinoderma larval metamorphosis and settlement, larvae of sea urchin and sea cucumber were investigated.
Sea urchin larval metamorphosis was induced by water soluble extract of the green alga Ulvella lens, which is used at aquaculture facilities. The active component of the extract was identified as phenylalanine. Phenylalanine showed metamorphosis inducing activity at 5 μM. However, the morphological change by the amino acid was different from the case induced by the alga itself. Combined effect of phenylalanine with other components was suggested.
Sea cucumber larval metamorphosis was investigated using a number of physiologically active compounds. As a result, dopamine, L-DOPA, L-adrenalin, and L-noradrenalin showed larval metamorphosis induction. Especially, dopamine showed strong activity. However, the effect of dopamine was slow-acting.
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