Project/Area Number |
17590536
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Public health/Health science
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
WATANABE Masafumi Tokyo Medical and Dental University, Division of Public Health, Research Associate (90280974)
|
Project Period (FY) |
2005 – 2007
|
Project Status |
Completed (Fiscal Year 2007)
|
Budget Amount *help |
¥3,750,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2005: ¥1,900,000 (Direct Cost: ¥1,900,000)
|
Keywords | social medicine / infectious disease / influenza virus / environment / megacity / PCR / airborne bacteria |
Research Abstract |
I tried to establish the detection method of airborne influenza virus by applying RT-PCR method. I could not detect airborne influenza virus steadily at this moment. Sampling method of airborne virus and shortage of the target RNA are considered as a cause of failure. Therefore, relationships between the detection of airborne influenza virus and its related factors such as airborne particles, airborne bacteria, the pattern of identified airborne bacteria, temperature, relative humidity, density of people and ventilation condition could not fully be verified. However, Characteristics of airborne particles and airborne bacteria and the relationships between those indicators and their related factors were elucidated in urban public space. Positive associations between number of airborne bacteria and number of the pedestrians, PM5.0 were indicated. Regarding the pattern of identified airborne bacteria, gram-positive bacteria were dominant and Staphylococcus spp., Micrococcus spp., Pseudomonas spp. were major bacteria as genus levels. Staphylococcus aureus and Streptococcus spp. which were suspected of pathogenicity were also identified. Availability of PM5.0 indicator as the predictive indicator of airborne pathogenic agents was suspected. I eagerly make efforts for the establishment of airborne pathogenic virus steadily from this time.
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