| Project/Area Number |
17591324
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SUGANO Norihide Tokyo Medical and Dental University, Hospital, Assistant Professor (60332631)
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Yoshinori Tokyo Medical and Dental University, Graduate School of Medicine, Lecturer (70280964)
岩井 武尚 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (90111591)
広川 雅之 東京医科歯科大学, 大学院医歯学総合研究科, 助手 (00315011)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,530,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2005: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | Surgery / Varicose vein / Operation / Less invasive treatment / Laser / 静脈瘤 |
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| Research Abstract |
Objective: To clarify the efficacy and safety of a 1320 nm endovenous laser treatment (ELVT).
Patients and Methods: Thirty-seven limbs in 32 patients with primary varicose veins were treated. Pulsed (50Hz) laser energy was applied at 5 Watts while the fiber was retracted at a speed of m/sec by the pull back system.
Results: Although the initial success (occlusion) rate was 100% and the venous filling index was almost normal at 1 year after treatment, the clinical recurrence rate was 16.2% after a mean follow-up period of 633 days. The linear endovenous energy density (LEED) was significantly lower in the limbs with recurrence (45.5±5.6 vs. 52.3±12.3 J/cm, p<0.05). There was no major complication. Minor complications included 4 moderate bruising, 6 mild pains, and 1 saphenous nerve injury.
Conclusion: 1320 nm EVLT was a safe and effective treatment, but a LEED of greater than 50 J/cm might be necessary to occlude the saphenous vein sufficiently.
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