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Automated diagnosis of mammary cancer lymph node micrometastasis by real time PCR and FCM

Research Project

Project/Area Number 17591355
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionNippon medical school

Principal Investigator

TENJIN Toshihito  Nippon medical school, 医学部, 准教授 (70217438)

Co-Investigator(Kenkyū-buntansha) 清水 一雄  日本医科大学, 医学部, 教授 (20133449)
赤須 東樹  日本医科大学, 医学部, 講師 (30297866)
田中 久美  日本医科大学, 医学部, 助教 (50343603)
北川 亘  日本医科大学, 医学部, 講師 (80297895)
Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,340,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2006: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2005: ¥1,400,000 (Direct Cost: ¥1,400,000)
Keywordsbreast cancer / Flow cytometry / Real-time PCR / フローサイトメトリー / Real-time(quantitative)PCR / フローサイトメトリー(FCM) / CEA / サイトケラチン / 乳癌培養細胞
Research Abstract

Lymph node micrometastasis of breast cancer is important problem. Therefore we review lymph node micrometastasis by Real-time quantitative PCR and flow cytometry. Lymph node micrometastasis is diagnosed in pathology, but it is difficult to image lymph node. Measuring the whole lymph node using Real-time PCR and FCM, we establish diagnostic procedure to prove extremely small carcinoma in high sensitivity.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (3 results)

All 2007

All Presentation (3 results)

  • [Presentation] センチネルリンパ節癌微小転移の観察に対する基礎的研究.2007

    • Author(s)
      天神敏博
    • Organizer
      第17回日本サイトメトリー学会
    • Place of Presentation
      東京
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] study for observation of sentinel lymph node carcinoma micrometastasis.cytometry society2007

    • Organizer
      The 17th annual meeting of the Japan
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-06-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 蛍光二重染色法を用いたセンチネルリンパ節癌微小転移の観察法に対する基礎的研究2007

    • Author(s)
      天神敏博、
    • Organizer
      第15回日本乳癌学会
    • Place of Presentation
      東京
    • Related Report
      2007 Annual Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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