| Project/Area Number |
17591491
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Kanto Gakuin University |
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Principal Investigator |
AKUTSU Toshinosuke Kanto Gakuin University, College of Engineering, Prof., 工学部, 教授 (90231852)
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| Co-Investigator(Kenkyū-buntansha) |
MITSUMASA Umezu Waseda Univ., School of science and engineering, Prof, 理工学部, 教授 (90132927)
NIINAMI Hiroshi Juntendo Univ., School of Medicine, Associate Prof, 医学部, 助教授 (30241079)
IWASAKI Kiyotaka Waseda Univ., School of science and engineering, Assistant Prof, 生命医療工学研究所, 講師 (20339691)
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| Project Period (FY) |
2005 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2005: ¥2,800,000 (Direct Cost: ¥2,800,000)
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| Keywords | Cardiac Surgery / Circulatory system / Bio-engineering / Fluid Engineering |
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| Research Abstract |
The purpose of this research is to grasp the influence of the leaflet and overall design differences on the flow field inside the valsalva and to clarify the influence of these differences on the coronary flow when the valve is equipped at aortic location. By utilizing the previously developed Aorta and experience accumulated in constructing simulation device, new Aorta model simulating aortic characteristic was planned and constructed and used it to analyze the influence of overall valve and leaflet design on the flow field inside the valsalva and on the coronary circulation by using DynamicPIV system
In the first research year, we planed to construct prototype Aorta model and planed execution of pre-experiment to establish analytical method using DynamicPIV system. Pre-experiment using newly constructed prototype Aorta model was executed using the MIRA valve and the SJM valve as test valves, resulted in finding substantial differences on the generated flow.
Above-mentioned new analytical method was purposely tried at trusted mitral valve location, where enough data was accumulated for evaluation, to find the influence of the valve designs on the mitral flow field. Some results were already reported through international and domestic conferences.
In the last research year, we constructed final silicone Aorta model with valsalva. It was equipped in the simulation device and experiment was conducted. As a result, flow field influenced by the mechanical bi-leaflet valve was obtained in detail and was able to grasp the flow phenomenon inside the valsalva. With this time-resolved information in hand, we were able to grasp the influence of flow field to the coronary circulation.
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