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Study of Blue Cone under Pathological Conditions in Rabbit Eyes

Research Project

Project/Area Number 17591821
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionChiba University

Principal Investigator

YAMAMOTO Shuichi  Chiba University, Graduate School of Medicine, Professor, 大学院医学研究院, 教授 (20230550)

Co-Investigator(Kenkyū-buntansha) YOTSUKURA Jiro  Chiba University, Hospital, Assistant Professor, 医学部附属病院, 講師 (00240367)
水野谷 智  千葉大学, 大学院・医学研究院, 講師 (50322029)
Project Period (FY) 2005 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2006: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2005: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsElectroretinogram / Blue cone / LED built-in contact lens electrode / Retinal degeneration / Rabbit eye
Research Abstract

1) To examine the blue cone electroretinogram, we developed the blue LED built-in contact lens electrode.
2) Responses from the blue cone were clearly and repeatedly recorded from normal human eyes using this new electrode.
3) Temporal frequency characteristics obtained from the electroretinogram was quite similar those reported in previous psychophysical studies.
4) Smaller contact lenses were developed for rabbit eyes, and the blue cone electroretinograms were successfully recorded.
5) Electroretinograms were examined in patients with various retinal diseases, and in several animal models.

Report

(3 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • Research Products

    (15 results)

All 2006 2005

All Journal Article (15 results)

  • [Journal Article] Correlation of retinal sensitivity measured with fundus-related microperimetry to visual acuity and retinal thickness in eyes with diabetic macular edema2006

    • Author(s)
      Okada K
    • Journal Title

      Eye 20

      Pages: 805-809

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Case of dominantly inherited drusen accompanied by choroidal neovascularization2006

    • Author(s)
      Yamamoto S
    • Journal Title

      Jpn J Ophthalmol 50

      Pages: 73-75

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Arpclb gene is a candidate prediction marker for choroidal malignant melanomas sensitive to radiotherapy2006

    • Author(s)
      Kumagai K
    • Journal Title

      Invest Ophthalmol Vis Sci 47

      Pages: 2300-2304

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina2006

    • Author(s)
      Adachi-Uehara N
    • Journal Title

      Exp Eye Res 83

      Pages: 849-857

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Correlation of retinal sensitivity measured with fundus-related microperimetry to visual acuity and retinal thickness in eyes with diabetic macular edema.2006

    • Author(s)
      Okada K, Yamamoto S, Mizunoya S, Hoshino A, Arai M, Takatsuna Y
    • Journal Title

      Eye 20

      Pages: 805-809

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Pattern visual evoked potentials in eyes with disc swelling due to cat scratch disease-associated neuroretinitis.2006

    • Author(s)
      Chai Y, Yamamoto S, Hirayama A, Yotsukura J, Yamazaki H
    • Journal Title

      Doc Ophthalmol 50

      Pages: 73-75

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Case of dominantly inherited drusen accompanied by choroidal neovascularization.2006

    • Author(s)
      Yamamoto S, Yagi F, Kubota M, Mizunoya S.
    • Journal Title

      Jpn J Ophthalmol 50

      Pages: 73-75

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Arpc1b gene is a candidate prediction marker for choroidal malignant melanomas sensitive to radiotherapy.2006

    • Author(s)
      Kumagai K, Nimura Y, Mizota A, Miyahara N, Aoki M, Furusawa Y, Takiguchi M, Yamamoto S, Seki N.
    • Journal Title

      Invest Ophthalmol Vis Sci 47

      Pages: 2300-2304

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Up-regulation of genes for oxidative phosphorylation and protein turnover in diabetic mouse retina.2006

    • Author(s)
      Adachi-Uehara N, Kato M, Nimura Y, Seki N, Ishihara A, Matsumoto E, Iwase K, Ohtsuka S, Kodama H, Mizota A, Yamamoto S, Adachi-Usami E, Takiguchi M.
    • Journal Title

      Exp Eye Res. 83

      Pages: 849-857

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Arpc1b gene is a candidate prediction marker for choroidal malignant melanomas sensitive to radiotherapy2006

    • Author(s)
      Kumagai K
    • Journal Title

      Invest Ophthalmol Vis Sci 47

      Pages: 2300-2304

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Deterioration of visual function as examined by electroretinograms in Toxoplasma gondii-infected IFN-gamma-knockout mice2005

    • Author(s)
      Norose K
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 317-321

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Pattern visual evoked potentials in eyes with disc swelling due to cat scratch disease-associated neuroretinitis2005

    • Author(s)
      Chai Y
    • Journal Title

      Doc Ophthalmol 110

      Pages: 271-275

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Deterioration of visual function as examined by electroretinograms in Toxoplasma gondii-infected IFN-gamma-knockout mice.2005

    • Author(s)
      Norose K, Aosai F, Mizota A, Yamamoto S, Mun HS, Yano A
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 317-321

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Central retinal artery occlusion after radial optic neurotomy in a patient with central retinal vein occlusion2005

    • Author(s)
      Yamamoto S
    • Journal Title

      Am J Ophthalmol 139

      Pages: 206-206

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Correlation of retinal sensitivity measured with fundus-related microperimetry to visual acuity and retinal thickness in eyes with diabetic macular edema2005

    • Author(s)
      Okada K
    • Journal Title

      Eye (Epub ahead of print)

    • Related Report
      2005 Annual Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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