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Free electron laser ablation effects and its application for dental enamel and dentin

Research Project

Project/Area Number 17591927
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionNihon University

Principal Investigator

SAKAE Toshiro  Nihon University, School of Dentistry at Matsudo, Associate Professor (20112948)

Co-Investigator(Kenkyū-buntansha) OKADA Hiroyuki  Nihon University, School of Dentistry at Matsudo, Assistant Professor (70256890)
SATO Isamu  Nihon University, Advanced research Institute for the Sciences and Humanities, Professor (30013387)
Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,680,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2006: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2005: ¥2,100,000 (Direct Cost: ¥2,100,000)
KeywordsFree Electron Laser / Tooth / Hard Tissue / ablation / Tunable Wavelength / High Power / Thermal Damge / Free Electron Laser / 可変波長 / 自由電子レーザー / 直線電子線加速器 / 切削 / 結晶 / エナメル質 / 象牙質 / ablation / レーザー波長 / レーザー切削
Research Abstract

This study aimed to evaluate the laser ablation effect for dental hard tissues, and a free electron laser (FEL) with tunable wavelength was applied. The wavelength of FEL operated at Laboratory for Electron Beam Research and Application (LEBRA), Nihon University, was tuned from 1.0 μm to 6.0 μm. Human tooth sections were irradiated by the LEBRA-FEL. Fore-going studies revealed that the LEBRA-FEL effectively formed pits by irradiation almost similar to the usual dental Er : YAG lasers, wavelength of 2.94 μm. In this study, to reveal mechanism of the LEBRA-FEL ablation for dental hard tissues in more details, a gypsum sample was used as an indicator of thermal history during the irradiation experiment. After the irradiation, there was no remains which indicated the heating ablation effect being over 100 degrees Celsius by means of X-ray diffraction, differential thermal analysis, micro-FTIR and micro-Raman analysis. By video recording of the irradiation, minute particles were discharged from the irradiation spot. These results suggested that the ablation of such a kind of plasma ablation. In conclusion, the traditional explanation of laser irradiation ablation was due to micro-burst of water molecules contained in the materials should be re-examined, and seek another possible theory which may satisfy the FEL irradiation results in this study.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (46 results)

All 2008 2007 2006 2005 2003

All Journal Article (29 results) (of which Peer Reviewed: 11 results) Presentation (17 results)

  • [Journal Article] Quantitative Micro-Radiography of New Bones Formed Around the Implant Using Parametric X-ray2008

    • Author(s)
      T. Suwa
    • Journal Title

      Key Engineering Materials 361-363

      Pages: 1249-1252

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Quantitative Micro-Radiography of New Bones Formed Around the Implant Using Parametric X-ray2008

    • Author(s)
      T., Suwa, et. al.
    • Journal Title

      Key Engineering Materials 361-363

      Pages: 1249-1252

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 象牙の象牙質コラーゲンの示差熱分析・熱重量分析2007

    • Author(s)
      寒河江 登志朗
    • Journal Title

      亀井節夫先生傘寿記念論文集

      Pages: 99-103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 微小部X線回折によるラット大腿骨の加齢変化の研究2007

    • Author(s)
      諏訪 武利
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 215-217

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 口腔内細菌の532nmレーザー顕微Raman分析2007

    • Author(s)
      長瀬 あゆみ
    • Journal Title

      Journal of Hard issue Biology 16

      Pages: 205-208

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Thermal aBlation of FEL Irradiation Using Gypsum as an Indicator2007

    • Author(s)
      T. Sakae
    • Journal Title

      Lasers in Medical Science 22

      Pages: 15-20

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 顎関節の偽痛風にみられた結晶物分析の一考察2007

    • Author(s)
      森川 美雪
    • Journal Title

      日大口腔科学 33

      Pages: 42-45

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analysis of Liquid Specimen in a Glass ampoule by 532 nm Laser2007

    • Author(s)
      T. Sakae
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 143-145

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Quantitative radiographic study of new bone formed around the Implant using a parametric X-ray method2007

    • Author(s)
      T. Suwa
    • Journal Title

      journal尾fHard Tissue Biology 16

      Pages: 139-141

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Thermogravimetric and differential thermal analysis study of ivory dentin collagen2007

    • Author(s)
      T., Sakae, et. al.
    • Journal Title

      Jubilee Publication in Commemoration of Prof. Kamei Tadao's 80th Birthday 99-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A study of age-related changes of rat thighbone by the micro-XRD2007

    • Author(s)
      T., Suwa, et. al.
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 215-217

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 532 nm Laser Raman Analysis of Intraoral Bacterium2007

    • Author(s)
      A., Nagase, et. al.
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 205-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Thermal aBlation of FEL Irradiation Using Gypsum as an Indicator2007

    • Author(s)
      T., Sakae, et. al.
    • Journal Title

      Lasers in Medical Science 22

      Pages: 15-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A consideration of crystal analysis of Pseudogout in temporomandibular joint2007

    • Author(s)
      M., Morikawa, et. al.
    • Journal Title

      Nihon Univ. Journal of Oral Science 33

      Pages: 42-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Analysis of Liquid Specimen in a Glass ampoule by 532 nm Laser2007

    • Author(s)
      T., Sakae, et. al.
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 143-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Quantitative radiographic study of new bone formed around the Implant using a parametric X-ray method2007

    • Author(s)
      T., Suwa, et. al.
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 139-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 硬組織の質的評価にMicro FTRamanを使用した基礎的研究2007

    • Author(s)
      沼田靖子
    • Journal Title

      Journal of Hard Tissue Biology 16

      Pages: 209-213

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermal ablation of FEL irradiation using gypsum as an indicator.2007

    • Author(s)
      寒河江登志朗
    • Journal Title

      Lasers in medical Sciences 22

      Pages: 15-20

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] thermal ablation of FEL irradiation using gypsum as an indicator2007

    • Author(s)
      Sakae T
    • Journal Title

      Leaers in Medical Science 22

      Pages: 15-20

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Quantitative Radiographic Study of New Bone Formed around the Implant using a Newly developed Parametric X-ray Method2006

    • Author(s)
      T. Sakae
    • Journal Title

      Asian Bioceramics Symposium 6

      Pages: 194-196

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Quantitative Radiographic Study of New Bone Formed around the Implant using a Newly developed Parametric X-ray Method [ RESEARCH PRESENTATIONS ]2006

    • Author(s)
      T., Sakae, et. al.
    • Journal Title

      Asian Bioceramics Symposium 6

      Pages: 194-196

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Quantitative radiographic study of new bone formed around the implant using a newly developed parametric x-ray method2006

    • Author(s)
      Sakae T
    • Journal Title

      Asian Bioceramics 2006 1

      Pages: 194-196

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Observation of newly formed bone around dental implants using Parametric X-ray2006

    • Author(s)
      H.Nakada
    • Journal Title

      Key Engineering Materials 309-311

      Pages: 31-34

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Variation in composition of bone surrounding implant2006

    • Author(s)
      T.Suwa
    • Journal Title

      Key Engineering Materials 309-311

      Pages: 19-22

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Characterization and bioactivity of tape-cast and sintered TCP sheets2006

    • Author(s)
      Y.Tanimoto
    • Journal Title

      Journal Biomedical Materials research 76A

      Pages: 571-579

    • Related Report
      2005 Annual Research Report
  • [Journal Article] パラメトリックX線と歯科用X線を比較したインプラント周囲の新生骨の観察2005

    • Author(s)
      中田浩史
    • Journal Title

      日大口腔科学 31・2

      Pages: 110-115

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 表面処理を施したチタンインプラント周囲新生骨のMicro-CTによる観察2005

    • Author(s)
      中田浩史
    • Journal Title

      再生歯誌 3・1

      Pages: 24-40

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Pit formation in human enamel and dentin irradiated using the 2.94μm LEBRA-Free electron laser2005

    • Author(s)
      T.Sakae
    • Journal Title

      International Journal of Oral-Medical Sciences 4・1

      Pages: 8-13

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Application of LEBRA-PXR to the diffraction analysis of minerals2003

    • Author(s)
      T.Sakae
    • Journal Title

      Journal of Mineralogical and Petrological Sciences 101

      Pages: 10-13

    • NAID

      10016735578

    • Related Report
      2005 Annual Research Report
  • [Presentation] 歯の硬組織に対するLEBRA-FEL照射実験2008

    • Author(s)
      寒河江 登志朗
    • Organizer
      第1回FEL-TUSイノベーションセミナー
    • Place of Presentation
      東京理科大学神楽坂校舎
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Lebra-FEL irradiation on dental hard tissues2008

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      1st FEL-TUS Innovation Seminar
    • Place of Presentation
      Kagurazaka campus, Tokyo University of Science
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 歯の硬組織に自由電子レーザー照射したときのレーザー波長依存性とプラズマ・アブレーション2007

    • Author(s)
      寒河江登志朗
    • Organizer
      第28回日本レーザー医学会総会シンポジウム2「レーザー光計測・制御システムの新開発」
    • Place of Presentation
      旭川市民文化会館
    • Year and Date
      2007-09-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 歯の硬組織にFEL(自由電子レーザー)照射したときのレーザー波長依存性とプラズマ・アブレーション2007

    • Author(s)
      寒河江 登志朗
    • Organizer
      第28回日本レーザー医学会総会
    • Place of Presentation
      旭川
    • Year and Date
      2007-09-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Laser Wavelength Dependency and Plasma Ablation when LEBRA-FEL Irradiated on Dental Hard Tissues2007

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      28th Annual Meeting of Japan Society for Laser Surgery and Medicine
    • Place of Presentation
      Asahikawa
    • Year and Date
      2007-09-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Wavelength dependency of dental hard tissue ablation shown by FEL2007

    • Author(s)
      T. Sakae
    • Organizer
      International Association for Dental Research
    • Place of Presentation
      New Orleans,USA
    • Year and Date
      2007-03-24
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Wavelength dependency of dental hard tissue ablation shown by FEL2007

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      Inter Association for Dental Research
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2007-03-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 歯の硬組織に対するLEBRA-FELアブレーション2007

    • Author(s)
      寒河江 登志朗
    • Organizer
      平成19年度文部科学省学術フロンティア推進事業(継続)「可変波長高輝度単色光源の高度利用に関する研究」研究成果発表シンポジウム
    • Place of Presentation
      日本大学理工学部船橋校舎
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] LEBRA-FEL Ablation for Dental Hard Tissues2007

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      Symposium for the Academic Frontier Project, Advanced Application of Tunable Wavelength and High Brilliant Monochromatic Source (2005-2007)
    • Place of Presentation
      Nihon University,Funabashi
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Quantitative radiographic study of new bone formed around the Implant using a newly developed parametric X-ray method2006

    • Author(s)
      T. Sakae
    • Organizer
      6th Asian Bioceramics Symposium
    • Place of Presentation
      Bangkok,Thailand
    • Year and Date
      2006-11-07
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Quantitative radiographic study of new bone formed around the Implant using a newly developed parametric X-ray method2006

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      6th Asian Bioceramics Symposium
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2006-11-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FEL ablation effect on human dental enamel and dentin2005

    • Author(s)
      T. Sakae
    • Organizer
      Japanese Association for Dental Research
    • Place of Presentation
      岡山大学
    • Year and Date
      2005-11-26
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FEL ablation effect on human dental enamel and dentin2005

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      Japanese Ass for Dental Research
    • Place of Presentation
      Okayama University
    • Year and Date
      2005-11-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Wavelength dependency of FEL irradiated dental enamel and dentinpit formation2005

    • Author(s)
      T. Sakae
    • Organizer
      16th World Congress of the International Society for Laser Surgery and Medicine
    • Place of Presentation
      東京
    • Year and Date
      2005-09-07
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Wavelength dependency of FEL irradiated dental enamel and dentin pit formation2005

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      16th World Congress of the International society for Laser Surgery & Medicine
    • Place of Presentation
      Tokyo
    • Year and Date
      2005-09-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] LEBEA-PXR to FELの生体硬組織への応用研究「化石鉱物からインプラントまで」2005

    • Author(s)
      寒河江登志朗
    • Organizer
      平成17年度文部科学省学術フロンティア推進事業(継続)「可変波長高輝度単色光源の高度利用に関する研究」研究成果発表シンポジウム
    • Place of Presentation
      日本大学理工学部船橋校舎
    • Year and Date
      2005-03-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Application of LEBRA-PXR and FEL to Study of Biological Hard Tissues- from Fossil mineral to Implant2005

    • Author(s)
      T., Sakae, et. al.
    • Organizer
      Symposium for the Academic Frontier Project, Advanced Application of Tunable Wavelength and High Brilliant Monochromatic Source (2005-2007)
    • Place of Presentation
      Nihon University, Funabashi
    • Year and Date
      2005-03-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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