| Co-Investigator(Kenkyū-buntansha) |
KATO Kiminori Niigata University, Medical and Dental Hospital, Assistant, 医歯学総合病院, 助手 (00303165)
HANAWA Haruo Niigata University, Institute of Medicine and Dentistry, Lecturer, 医歯学系, 講師 (40282983)
KODAMA Makoto Niigata University, Institute of Medicine and Dentistry, Associate professor, 医歯学系, 助教授 (10242447)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2005: ¥3,000,000 (Direct Cost: ¥3,000,000)
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| Research Abstract |
Results (1) To delineate the epidemiological and clinical characteristics of systolic dysfunction (SD) patients, the medical records of Sado Island were collected and summarized in 2003. During the 5 years prior to 2003, 497 patients were extracted. The mortality rate was significantly higher compared to the general population ; and the total number of survivors decreased to 410 by 2003. The proportion of SD patients in the general population increased sharply after the age of 65 in males and 70 years in females, reaching 3.3% and 1.7% for men and women in their 80s. In 49% of the patients, Charlson comorbidity index was 【greater than or equal】2, whereas 24% of females led a solitary life.
Results (2) The medical information of all outpatients with moderate to severe isolated diastolic dysfunction (IDD) was extracted from the records of about 6,948 individuals who underwent echocardiographic (Echo) examinations during the past 5 years in Sado Island. From the 284 patients extracted, 272 survived until 2003. The proportion of patients with moderate to severe IDD in the general population sector aged 45-84 years was 0.9% for males and 0.5% for females in January 2003. This proportion increased sharply after the age of 65 in both genders, reaching 1.6% for men in their 70s and 0.8% for women in their 80s. On Echo, 165 patients (61%) showed hypertrophic left ventricular geometry. Charlson comorbidity index score was 【less than or equal】1 in 63% of patients. The cumulative survival of IDD patients, irrespective of history of congestive heart failure (CHF), was significantly lower compared with the general population.
Results (3) Hypertension, diabetes, dyslipidemia, history of hospital admission due to CHF, myocardial infarction, atrial fibrillation, and stroke were more prevalent in Niigata than in Sado, but not significant except history of hospital admission due to CHF in elderly male (P<0.013).
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