気道の炎症性疾患における気道粘膜透過性亢進の機序とその治療戦略について

• Project/Area Number: 17659246
• Research Category: Grant-in-Aid for Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Respiratory organ internal medicine
• Research Institution: Yokohama City University
• Principal Investigator: 金子 猛 Yokohama City University, 附属市民総合医療センター, 教授 (90275066)
• Project Period (FY): 2005 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥3,200,000 (Direct Cost: ¥3,200,000); Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000); Fiscal Year 2006: ¥1,100,000 (Direct Cost: ¥1,100,000); Fiscal Year 2005: ¥1,000,000 (Direct Cost: ¥1,000,000)
• Keywords: 気道粘膜透過性 / オゾン / 血管透過性 / 気道上皮細胞 / 気道炎症 / モルモット / HO-1 / 喘息 / 好酸球 / Hemin / ZnPP

Research Abstract

作成中

Research Products

• [Journal Article] PIK3CA mutation and amplification in human lung cancer. (2007)
  • Author(s): Okudela K, Suzuki M, Kageyama S, Bunai T, Nagura K, Igarashi H, Takamochi K, Suzuki K, Yamada T, Niwa H, Ohashi R, Ogawa H, Mori H, Kitamura H, Kaneko T, Tsuneyoshi T, Sugimura H.
  • Journal Title: Pathol Int 57 Pages: 664-667
  • NAID: 10021233920
  • Peer Reviewed
• [Journal Article] Tuberculosis in patients with rheumatoid arthris and screening by ELISPOT technique. (2007)
  • Author(s): Miura K, Takeno M, Murakami S, Watanabe R, Ueda A, Kaneko T, Ishigatsubo Y.
  • Journal Title: Yokohama Medical Journal 58 Pages: 83-89
  • Peer Reviewed
• [Journal Article] Metastatic brain mass caused by slow-growing small-cell lung cancer: differential vascular endothelial growth factor expression in primary and metastatic tumor. (2007)
  • Author(s): Inoue S, Oshiro H, Watanuki Y, Miyazawa N, Kudo M, Goto H, Tsukiji J, Kaneko T, Ishigatsubo Y.
  • Journal Title: Clin Lung Cancer 8 Pages: 436-438
  • Peer Reviewed
• [Journal Article] Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury. (2006)
  • Author(s): Sato T, Kaneko T, et al.
  • Journal Title: Am J Respir Crit Care Med 174・8 Pages: 906-914
• [Journal Article] Large cell carcinoma of the lung with rhabdoid phenotype の1例。 (2006)
  • Author(s): 後藤秀人, 伊藤優, 山口展弘, 高橋健一, 河野尚美, 金子猛, 石ヶ坪良明
  • Journal Title: 日本呼吸器学会雑誌 44・4 Pages: 325-329
  • NAID: 10018188421
• [Journal Article] Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lungs attenuates elastase-induced pulmonary emphysema in mice. (2005)
  • Author(s): Shinohara T, Kaneko T, et al.
  • Journal Title: Human Gene Ther 16(3) Pages: 318-327
• [Journal Article] Heme oxygenase-1 inhibits cigarette smoke-induced increase in the tracheal mucosal permeability in guinea pigs in vivo. (2005)
  • Author(s): Tagawa A, Kaneko T, et al.
  • Journal Title: Inflamm Res 54(5) Pages: 229-234
• [Journal Article] Cigarette smoke increases mucosal permeability in guinea pig trachea via tachykinin NK_2 receptor activation. (2005)
  • Author(s): Tagawa A.Kaneko T, et al.
  • Journal Title: Eur J Pharmacol 507(1-3) Pages: 223-228
• [Journal Article] Isoniazid and Isoniazid and food interactions-fish, cheese, and wine. (2005)
  • Author(s): Kaneko T, Ishigtsubo Y
  • Journal Title: Intern Med 44(11) Pages: 1120-1121
• [Presentation] Heme oxygenase-1 inhibits an antigen-induced increase in the tracheal mucosal permeability in guinea pigs in vivo. (2007)
  • Author(s): Shinohara T, Kaneko T, Tagawa A, Takashi H, Nishikawa M, Watanuki Y, Ishigatsubo Y.
  • Organizer: American Thoracic Society International Conference
  • Place of Presentation: San Francisco
• [Book] 肺疾患と歯周病:Preventive Periodontology (2007)
  • Author(s): 金子猛
  • Total Pages: 5
  • Publisher: 医歯薬出版株式会社