| Budget Amount *help |
¥43,290,000 (Direct Cost: ¥33,300,000、Indirect Cost: ¥9,990,000)
Fiscal Year 2020: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2018: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2017: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
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| Outline of Final Research Achievements |
The purpose of this research was to elucidate the principles for accelerating biochemical reactions by light-induced condensation of a wide variety of nano- and micro-scale bio-related substances, and to create an on-demand "light-induced acceleration system" that enables rapid and highly efficient bioanalysis and drug delivery with a simple configuration. Through multi-disciplinary collaborative research in bio-photophysics, analytical chemistry, and chemical biology, we have elucidated new principles for stable light-induced acceleration of biochemical reactions and low-damage optical condensation of biomaterials such as nucleic acids and proteins at the solid-liquid interface. Based on these achievements, we achieved in establishing the foundation for rapid and highly sensitive bioanalysis technology and highly efficient delivery technology of bioactive substances to cells, and pioneered a new photo-biotechnology.
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