| Budget Amount *help |
¥42,120,000 (Direct Cost: ¥32,400,000、Indirect Cost: ¥9,720,000)
Fiscal Year 2021: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2020: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2019: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2018: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2017: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Outline of Final Research Achievements |
Autophagy is a major degradation system in eukaryotic cells. This study aimed at elucidating the mechanisms and physiological significance of organelle degradation by autophagy. Consequently, we revealed the mechanisms by which the nucleus and endoplasmic reticulum are deformed and sequestered within autophagosomes. We also showed how cells regulate autophagic degradation of peroxisomes. These results were published in international journals as three research articles. Moreover, our results provided significant insights into the regulation and physiological function of autophagy of the nucleus. These results will also be published soon.
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