| Budget Amount *help |
¥42,380,000 (Direct Cost: ¥32,600,000、Indirect Cost: ¥9,780,000)
Fiscal Year 2020: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2019: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2018: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2017: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
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| Outline of Final Research Achievements |
The ribosomal RNA genes (rDNA) are the most abundant gene in the eukaryotic cells and they make huge tandem clusters on the chromosome. Though the copy number maintenance is quite important for stable production of ribosome that translates mRNA to protein, the mechanism has not been elucidated. We identified the system for copy number monitoring, amplification induction and maintenance of the proper copy number by the rDNA transcription activating factor, UAF.
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