Characterization of endosymbiotic evolution by focusing on the mechanisms for coping with photosynthetic oxidative stress
| Project/Area Number |
17H01446
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Evolutionary biology
|
|---|
| Research Institution | National Institute of Genetics |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2017-04-01 – 2021-03-31
|
| Project Status |
Completed (Fiscal Year 2020)
|
| Budget Amount *help |
¥41,860,000 (Direct Cost: ¥32,200,000、Indirect Cost: ¥9,660,000)
Fiscal Year 2019: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2018: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2017: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
|
|---|
| Keywords | 細胞内共生 / 光合成 / 酸化ストレス / 細胞分裂 / 葉緑体 |
|---|
| Outline of Final Research Achievements |
It is believed that chloroplasts were established through predation and the temporary or facultative retention of photosynthetic prey and then permanent endosymbiotic relationship with photosynthetic organisms (or chloroplasts) by a unicellular eukaryotic host cell. In this study, we have analyzed how organisms in different stages of endosymbiotic evolution cope with photosynthetic oxidative stress. We have found that some mechanisms for coping with photosynthetic oxidative stress had been acquired stepwisely in prey-predator and temporal endosymbiotic relationships before establishment of permanent endosymbiotic relationships (chloroplasts).
|
| Academic Significance and Societal Importance of the Research Achievements |
光合成酸化ストレスへの対処機構は、すでに葉緑体との絶対共生関係を確立させている真核藻類・植物においての研究例があったが、本研究により、捕食―被食関係の段階においても真核藻類・植物に見られる機構の一部が成立していたことが初めて明らかとなった。また、これまでほとんど不明であった細胞内共生進化の初期段階について、絶対共生関係を構築するために必要な機構や遺伝子群を、宿主細胞が捕食―被食関係の段階から漸進的に獲得したという知見が得られた。これらの結果は、細胞内共生進化を理解するために重要な、これまでになかった視点からの発見である。
|
Report
(4 results)
Research Products
(16 results)
-
[Journal Article] Responses of unicellular predators to cope with the phototoxicity of photosynthetic prey.2019
Author(s)
Uzuka, A., Kobayashi, Y., Onuma, R., Hirooka, S., Kanesaki, Y., Yoshikawa, H., Fujiwara, T., Miyagishima, S.
-
Journal Title
Nature Communications
Volume: 10
Issue: 1
DOI
Related Report
Peer Reviewed / Open Access
-
[Journal Article] Day/night separation of oxygenic energy metabolism and nuclear DNA replication in the unicellular red alga Cyanidioschyzon merolae2019
Author(s)
Miyagishima, S., Era, A., Hasunuma, T., Matsuda, M., Hirooka, S., Sumiya, N., Kondo, A., Fujiwara, T.
-
Journal Title
DOI
NAID
Related Report
Peer Reviewed / Open Access
-
-
[Journal Article] Integration of a Galdieria plasma membrane sugar transporter enables heterotrophic growth of the obligate photoautotrophic red alga Cynanidioschyzon merolae2019
Author(s)
Fujiwara, T., Hirooka, S., Mukai, M., Ohbayashi, R., kanesaki, Y., Watanabe, S., and Miyagishima, S.
-
Journal Title
Plant Direct
Volume: in press
Related Report
Peer Reviewed / Open Access
-
[Journal Article] Acidophilic green algal genome provides insights into adaptation to an acidic environment2017
Author(s)
Hirooka, S., Hirose, Y., Kanesaki, Y., Higuchi, S., Fujiwara, T., Onuma, R., Era, A., Ohbayashi, R., Uzuka, A., Nozaki, H., Yoshikawa, H., and Miyagishima, S.
-
Journal Title
Proc. Natl. Acad. Sci. USA.
Volume: 114
Issue: 39
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
