• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Toward an elucidation of transmission mechanisms and pathological conditions of leishmaniasis and Chagas disease

Research Project

Project/Area Number 17H01685
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Parasitology (including sanitary zoology)
Research InstitutionJichi Medical University

Principal Investigator

Kato Hirotomo  自治医科大学, 医学部, 教授 (00346579)

Co-Investigator(Kenkyū-buntansha) 久保 誠  北里大学, 医療衛生学部, 准教授 (40464804)
伊藤 誠  愛知医科大学, 公私立大学の部局等, 客員教授 (90137117)
高木 秀和  愛知医科大学, 医学部, 准教授 (90288522)
山本 雄一  琉球大学, 医学部附属病院, 講師 (00363672)
三森 龍之  熊本大学, 大学院生命科学研究部(保), 教授 (00117384)
Project Period (FY) 2017-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥41,860,000 (Direct Cost: ¥32,200,000、Indirect Cost: ¥9,660,000)
Fiscal Year 2021: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2020: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2019: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2018: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2017: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Keywordsリーシュマニア症 / シャーガス病 / ベクター / サシチョウバエ / サシガメ / リザーバー / 分子疫学 / リスク評価 / 血清診断 / リーシュマニア / トリパノソーマ / 疫学
Outline of Final Research Achievements

The objective of this study is to develop new tools for the assessment of infection and pathogenic risk and to conduct an epidemiological survey of the “neglected tropical diseases” leishmaniasis and Chagas disease. Through this study, the geographic distribution of Leishmania species in Peru and Ecuador was determined, and the prevalence of previously unknown Leishmania species were also reported. We also gained many new insights into the vectors and reservoirs of both parasitic diseases. In addition, we were able to establish new diagnostic and survey systems and apply them to local surveys and diagnostics. The results obtained in this study will lead not only to the rapid and accurate diagnosis of leishmaniasis and Chagas disease and the elucidation of the transmission mechanism, but also to the elucidation of the pathogenesis and the development of the treatments.

Academic Significance and Societal Importance of the Research Achievements

本研究でリーシュマニア原虫種の地理的分布を明らかにし、様々な遺伝子交雑株の存在も見出した。リーシュマニア症では類似した症状でも感染種によって治療薬への反応性が異なるという知見が蓄積されつつある。本研究成果は、各流行地の病態リスクを明らかにするだけでなく、治療薬の選択にも役立つと期待される。また、ベクターやリザーバーに関する成果は、ベクターや感染源を標的とした疾病制御につながると期待される。本研究を通して、様々な血清診断法、分子診断法を確立でき、そのいくつかはすでに流行国で診断・検査や疫学調査に応用され有用性が確認されている。これらは早期診断・早期治療を実現する有用なツールになると考えられる。

Report

(6 results)
  • 2023 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (138 results)

All 2024 2023 2022 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (19 results) Journal Article (47 results) (of which Int'l Joint Research: 35 results,  Peer Reviewed: 42 results,  Open Access: 28 results) Presentation (70 results) (of which Int'l Joint Research: 6 results,  Invited: 7 results) Book (1 results) Remarks (1 results)

  • [Int'l Joint Research] サンマルコス大学(ペルー)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] ルフナ大学(スリランカ)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] パスツール研究所(チュニジア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Universidad Nacional Mayor de San Marcos/Direccion Regional de Salud Amazonas(ペルー)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Ruhuna(スリランカ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Univ. Centrooccidental Lisandro Alvarado(ベネズエラ)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Icahn School of Medicine at Mount Sinai(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Univ. Catolica de Santiago de Guayaquil/Universidad Central del Ecuador/Universidad De Las Americas(エクアドル)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Instituto Nacional de Salud(ペルー)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Universidad Catolica de Guayaquil(エクアドル)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Ruhuna(スリランカ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Chiang Mai University/Naresuan University/Mahidol University(タイ)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Instituto Nacional de Salud(ペルー)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Universidad Catolica de Guayaquil(エクアドル)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Chiang Mai University/Naresuan University/Mahidol University(タイ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] カトリカ大学/キト中央大学(エクアドル)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] 国立サンマルコス大学(ペルー)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] チェンマイ大学/マヒドン大学/ナレースアン大学(タイ)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] A real-time PCR for quantification of parasite burden and its correlations with clinical characteristics and anti-rKRP42 IgG level in cutaneous leishmaniasis in Sri Lanka2024

    • Author(s)
      De Silva Nirmitha Lalindi、De Silva Viraji Nefertiti Hiromel、Weerasooriya Mirani Vasanthamala、Takagi Hidekazu、Itoh Makoto、Kato Hirotomo、Yahathugoda Thishan Channa
    • Journal Title

      Parasitology International

      Volume: 100 Pages: 102865-102865

    • DOI

      10.1016/j.parint.2024.102865

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mosquitoes Possess Specialized Cuticular Proteins That Are Evolutionarily Related to the Elastic Protein Resilin2023

    • Author(s)
      Ohkubo Sakura、Shintaku Tohki、Mine Shotaro、Yamamoto Daisuke S.、Togawa Toru
    • Journal Title

      Insects

      Volume: 14 Issue: 12 Pages: 941-941

    • DOI

      10.3390/insects14120941

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of host species on microbiota composition in Phlebotomus and Lutzomyia sand flies2023

    • Author(s)
      Tabbabi Ahmed、Mizushima Daiki、Yamamoto Daisuke S.、Kato Hirotomo
    • Journal Title

      Parasites & Vectors

      Volume: 16 Issue: 1 Pages: 310-310

    • DOI

      10.1186/s13071-023-05939-2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A rare sugar, allose, inhibits the development of Plasmodium parasites in the Anopheles mosquito independently of midgut microbiota2023

    • Author(s)
      Mizushima Daiki、Yamamoto Daisuke S.、Tabbabi Ahmed、Arai Meiji、Kato Hirotomo
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 13 Pages: 116291-116291

    • DOI

      10.3389/fcimb.2023.1162918

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diplogonoporiasis Following the Consumption of Raw Juvenile Japanese Anchovy2022

    • Author(s)
      Kaneko Junichi、Yamada Takanori、Kato Hirotomo、Ida Yuya、Yamada Kenta、Koda Megumu、Fukita Kyoichi、Takeshita Yu、Takahashi Kenichi、Takinami Masaki、Tsuji Atsushi、Nishino Masafumi、Takahashi Yurimi、Sasada Yuzo
    • Journal Title

      Internal Medicine

      Volume: 61 Issue: 18 Pages: 2813-2815

    • DOI

      10.2169/internalmedicine.8881-21

    • NAID

      130008164544

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2022-09-15
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Necrotizing Soft-Tissue Infection of the Trunk Resulting From Wound Caused by a Centipede: A Case Report2022

    • Author(s)
      Tanaka Yasutaka、Mato Takashi、Fujiya Shoma、Furuhashi Yuri、Takanosu Tomotaka、Watanabe Nobutaka、Shinjo Takafumi、Matsumura Tomohiro、Izawa Yoshimitsu、Yonekawa Chikara、Kato Hirotomo
    • Journal Title

      American Journal of Case Reports

      Volume: 23 Pages: 106602-106602

    • DOI

      10.12659/ajcr.937869

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ayaconin, a novel inhibitor of the plasma contact system from the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis2022

    • Author(s)
      Kawahori Satoru、Seki Chisato、Mizushima Daiki、Tabbabi Ahmed、Yamamoto Daisuke S.、Kato Hirotomo
    • Journal Title

      Acta Tropica

      Volume: 234 Pages: 106602-106602

    • DOI

      10.1016/j.actatropica.2022.106602

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of a Highly Sensitive Nested PCR and Its Application for the Diagnosis of Cutaneous Leishmaniasis in Sri Lanka2022

    • Author(s)
      De Silva Nirmitha Lalindi、De Silva Viraji Nefertiti Hiromel、Deerasinghe Arachchige Theja Hemapala、Rathnapala Upeksha Lakmini、Itoh Makoto、Takagi Hidekazu、Weerasooriya Mirani Vasanthamala、Kato Hirotomo、Yahathugoda Thishan Channa
    • Journal Title

      Microorganisms

      Volume: 10 Issue: 5 Pages: 990-990

    • DOI

      10.3390/microorganisms10050990

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Validation of an In-House ELISA Method in the Diagnosis of Cutaneous Leishmaniasis Caused by Leishmania donovani in Hambantota District, Sri Lanka2022

    • Author(s)
      De Silva Nirmitha Lalindi、De Silva Viraji Nefertiti Hiromel、Deerasinghe Arachchige Theja Hemapala、Rathnapala Upeksha Lakmini、Kato Hirotomo、Itoh Makoto、Takagi Hidekazu、Weerasooriya Mirani Vasanthamala、Yahathugoda Thishan Channa
    • Journal Title

      Microorganisms

      Volume: 10 Issue: 5 Pages: 921-921

    • DOI

      10.3390/microorganisms10050921

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells2021

    • Author(s)
      Eri H Hayakawa, Hirotomo Kato, Glenn A Nardone, Jiro Usukura
    • Journal Title

      Parasitology International

      Volume: 80 Pages: 102179-102179

    • DOI

      10.1016/j.parint.2020.102179

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] First molecular identification of Leishmania major in Phlebotomus papatasi in an outbreak cutaneous leishmaniasis area in Iraq2021

    • Author(s)
      Al-Bajalan Mariwan M.M.、Niranji Sherko S.、Al-Jaf Sirwan M.、Kato Hirotomo
    • Journal Title

      Acta Tropica

      Volume: 215 Pages: 105807-105807

    • DOI

      10.1016/j.actatropica.2020.105807

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prevalence of Genetically Complex Leishmania Strains With Hybrid and Mito-Nuclear Discordance2021

    • Author(s)
      Kato Hirotomo、Caceres Abraham G.、Gomez Eduardo A.、Tabbabi Ahmed、Mizushima Daiki、Yamamoto Daisuke S.、Hashiguchi Yoshihisa
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 11 Pages: 625001-625001

    • DOI

      10.3389/fcimb.2021.625001

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Liver-Directed AAV8 Booster Vaccine Expressing Plasmodium falciparum Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model2021

    • Author(s)
      Shahnaij M, Iyori M, Mizukami H, Kajino M, Yamagoshi I, Syafira I, Yusuf Y, Fujiwara K, Yamamoto DS, Kato H, Ohno N, Yoshida S
    • Journal Title

      Front Immunol

      Volume: 12 Pages: 612910-612922

    • DOI

      10.3389/fimmu.2021.612910

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Preclinical Evaluations of Modified Rice Hydrogel for Topical Ophthalmic Drug Delivery of Praziquantel on Avian Philophalmiasis2021

    • Author(s)
      Prompetch Treepecth、Chailorm Akawat、Tiwananthagorn Saruda、Buranapim Nithidol、Okonogi Siriporn、Kato Hirotomo、Katip Wasan、Mektrirat Raktham
    • Journal Title

      Pharmaceutics

      Volume: 13 Issue: 7 Pages: 952-952

    • DOI

      10.3390/pharmaceutics13070952

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Natural infections of Pintomyia verrucarum and Pintomyia maranonensis by Leishmania (Viannia) peruviana in the Eastern Andes of northern Peru2021

    • Author(s)
      Kato Hirotomo、Seki Chisato、Kubo Makoto、Gonzales-Cornejo Lizandro、Caceres Abraham G.
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 15 Issue: 4 Pages: e0009352-e0009352

    • DOI

      10.1371/journal.pntd.0009352

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Topical Treatment of Cutaneous Leishmaniasis: A Case Treated with A Glucantime-Based Lotion Experienced in Ecuador and A Mini Review2021

    • Author(s)
      Hashiguchi Yoshihisa、Nieto Lenin V.、Villegas Nancy C.、Gomez Eduardo A.、Kato Hirotomo
    • Journal Title

      Archives of Medical and Clinical Research

      Volume: 01 Issue: 01 Pages: 1-15

    • DOI

      10.51941/amcr.2021.1103

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] リーシュマニア症2021

    • Author(s)
      加藤大智
    • Journal Title

      別冊日本臨牀「呼吸器症候群(第3版)IV」

      Volume: 20 Pages: 216-220

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Salivary gland transcriptome of the Asiatic Triatoma rubrofasciata2020

    • Author(s)
      Mizushima Daiki、Tabbabi Ahmed、Yamamoto Daisuke S.、Kien Le Trung、Kato Hirotomo
    • Journal Title

      Acta Tropica

      Volume: 210 Pages: 105473-105473

    • DOI

      10.1016/j.actatropica.2020.105473

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Transcriptome data on salivary lipocalin family of the Asiatic Triatoma rubrofasciata2020

    • Author(s)
      Mizushima Daiki、Tabbabi Ahmed、Yamamoto Daisuke S.、Kien Le Trung、Kato Hirotomo
    • Journal Title

      Data in Brief

      Volume: 30 Pages: 105647-105647

    • DOI

      10.1016/j.dib.2020.105647

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Case Report: Successful Treatment with Miltefosine of Severe New World Mucosal Leishmaniasis Caused by Leishmania guyanensis2020

    • Author(s)
      Calvopina Manuel、Jijon Sara、Serrano Esteban、Kato Hirotomo
    • Journal Title

      The American Journal of Tropical Medicine and Hygiene

      Volume: 103 Issue: 2 Pages: 752-755

    • DOI

      10.4269/ajtmh.19-0867

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Nuclear and kinetoplast DNA analyses reveal genetically complex Leishmania strains with hybrid and mito-nuclear discordance in Peru2020

    • Author(s)
      Tabbabi Ahmed、Caceres Abraham G.、Bustamante Chauca T. Pershing、Seki Chisato、Choochartpong Yanisa、Mizushima Daiki、Yamamoto Daisuke S.、Hashiguchi Yoshihisa、Kato Hirotomo
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 14 Issue: 10 Pages: e0008797-e0008797

    • DOI

      10.1371/journal.pntd.0008797

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Leishmaniasis mucocutanea resistente al antimoniato de meglumina en pacientes pediatricas en Ecuador2020

    • Author(s)
      Aldaz Naranjo Maria Isabel、Rosero Carla、Romero Luz、Guevara Angel、Torres Margarita、Kato Hirotomo
    • Journal Title

      Piel

      Volume: 35 Issue: 10 Pages: 626-626

    • DOI

      10.1016/j.piel.2020.01.008

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Diagnosis by molecular pathology of an early and atypical histoplasmosis lesion in the duodenum of an immunocompromised patient: A case report2020

    • Author(s)
      Sumiyoshi Sayoko、Tanaka Shinichi、Kato Hirotomo、Takagi Kohji、Minamisaka Takashi、Noguchi Akira、Nakajima Takahiko、Imura Johji
    • Journal Title

      Biomedical Reports

      Volume: 14 Issue: 1 Pages: 1-1

    • DOI

      10.3892/br.2020.1382

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparative Analysis of Bacterial Communities in Lutzomyia ayacuchensis Populations with Different Vector Competence to Leishmania Parasites in Ecuador and Peru2020

    • Author(s)
      Tabbabi Ahmed、Watanabe Shinya、Mizushima Daiki、Caceres Abraham G.、Gomez Eduardo A、Yamamoto Daisuke S.、Cui Longzhu、Hashiguchi Yoshihisa、Kato Hirotomo
    • Journal Title

      Microorganisms

      Volume: 9 Issue: 1 Pages: 68-68

    • DOI

      10.3390/microorganisms9010068

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 新大陸のサシチョウバエについて2020

    • Author(s)
      加藤大智
    • Journal Title

      有害生物

      Volume: 17 Pages: 61-70

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Anthropophilic phlebotomine sand fly Lutzomyia species and search for the natural Leishmania infections in an area endemic for cutaneous leishmaniasis in Ecuador2020

    • Author(s)
      Hashiguchi Yoshihisa、Gomez Eduardo A.、Velez Lenin N.、Villegas Nancy V.、Kubo Makoto、Mimori Tatsuyuki、Hashiguchi Kazue、Kato Hirotomo
    • Journal Title

      Acta Tropica

      Volume: 203 Pages: 105287-105287

    • DOI

      10.1016/j.actatropica.2019.105287

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Natural Leishmania (Leishmania) mexicana infection and biting activity of anthropophilic sand fly Lutzomyia ayacuchensis in the Ecuadorian Andes2020

    • Author(s)
      Hashiguchi Yoshihisa、Hashiguchi Kazue、Zambrano Flavio C.、Parraga Francisco D.、Martillo Viriginia P.、Torres Edison X.、Velez Lenin N.、Villegas Nancy V.、Gomez Eduardo A.、Kato Hirotomo
    • Journal Title

      Acta Tropica

      Volume: 203 Pages: 105321-105321

    • DOI

      10.1016/j.actatropica.2019.105321

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells2020

    • Author(s)
      Kubo Makoto、Nagashima Ryuichi、Kurihara Mitsue、Kawakami Fumitaka、Maekawa Tatsunori、Eshima Koji、Ohta Etsuro、Kato Hirotomo、Obata Fumiya
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 5 Pages: 1890-1890

    • DOI

      10.3390/ijms21051890

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bioactivity of sand fly saliva2019

    • Author(s)
      Kato Hirotomo
    • Journal Title

      Medical Entomology and Zoology

      Volume: 70 Issue: 3 Pages: 133-136

    • DOI

      10.7601/mez.70.133

    • NAID

      130007733287

    • ISSN
      0424-7086, 2185-5609
    • Year and Date
      2019-09-25
    • Related Report
      2019 Annual Research Report
    • Open Access
  • [Journal Article] PCR-RFLP analyses of Leishmania species causing cutaneous and mucocutaneous leishmaniasis revealed distribution of genetically complex strains with hybrid and mito-nuclear discordance in Ecuador2019

    • Author(s)
      Kato Hirotomo、Gomez Eduardo A.、Seki Chisato、Furumoto Hayato、Martini-Robles Luiggi、Muzzio Jenny、Calvopina Manuel、Velez Lenin、Kubo Makoto、Tabbabi Ahmed、Yamamoto Daisuke S.、Hashiguchi Yoshihisa
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 13 Issue: 5 Pages: e0007403-e0007403

    • DOI

      10.1371/journal.pntd.0007403

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A synthetic male-specific sterilization system using the mammalian pro-apoptotic factor in a malaria vector mosquito2019

    • Author(s)
      Yamamoto Daisuke S.、Sumitani Megumi、Kasashima Katsumi、Sezutsu Hideki、Matsuoka Hiroyuki、Kato Hirotomo
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 8160-8160

    • DOI

      10.1038/s41598-019-44480-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses2019

    • Author(s)
      Kato H, Caceres AG, Seki C, Silupu Garcia CR, Holguin Mauricci C, Castro Martinez SC, Moreno Paico D, Castro Muniz JL et al.,
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 13 Issue: 6 Pages: e0007496-e0007496

    • DOI

      10.1371/journal.pntd.0007496

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Palm-size and one-inch gel electrophoretic device for reliable and field-applicable analysis of recombinase polymerase amplification2019

    • Author(s)
      H. Rathore, R. Biyani, H. Kato, Y. Takamura, M. Biyani
    • Journal Title

      Anal. Methods

      Volume: 11 Issue: 39 Pages: 4953-5072

    • DOI

      10.1039/c9ay01476d

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Loop-mediated isothermal amplification (LAMP): An advanced molecular point-of-care technique for the detection of Leishmania infection2019

    • Author(s)
      Nzelu Chukwunonso O.、Kato Hirotomo、Peters Nathan C.
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 13 Issue: 11 Pages: e0007698-e0007698

    • DOI

      10.1371/journal.pntd.0007698

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Autochthonous cutaneous leishmaniasis in urban domestic animals (Felis catus / Canis lupus familiaris) from central-western Venezuela.2019

    • Author(s)
      Paniz Mondolfi AE, Colmenares Garmendia A, Mendoza Perez Y, Hernandez-Pereira CE, Medina C, Vargas F, Sandoval D, Aguero J, Roman D, Forlano-Riera M, Salas Y, Peraza M, Romero P, Aldana F, Castillo T, Santeliz S, Perez G, Suarez-Alvarado MJ, Morales-Panza RJ, Kato H
    • Journal Title

      Acta Trop.

      Volume: 191 Pages: 252-260

    • DOI

      10.1016/j.actatropica.2019.01.006

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Venezuela’s humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region2019

    • Author(s)
      Grillet ME, Hernandez-Villena JV, Llewellyn MS, Paniz-Mondolfi AE, TamiA et al.
    • Journal Title

      Lancet Infect Dis.

      Volume: 印刷中 Issue: 5 Pages: e149-e161

    • DOI

      10.1016/s1473-3099(18)30757-6

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Leishmaniasis caused by Leishmania (Viannia) guyanensis in north-central Pacific region of Ecuador: A clinico-epidemiological feature.2018

    • Author(s)
      Gomez EA, Kato H, Edison X. Torres-Romero EX, Velez LN, Villegas NV, Martillo VP, Zambrano FC, Kubo M, Hashiguchi K, Hashiguchi Y.
    • Journal Title

      Acta Trop.

      Volume: 185 Pages: 204-211

    • DOI

      10.1016/j.actatropica.2018.05.016

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Molecular mass-screening for vector research on leishmaniasis2018

    • Author(s)
      Kato H, Caceres AG, Gomez EA, Hashiguchi Y
    • Journal Title

      J Integrated Omics.

      Volume: 8 Issue: 3 Pages: 15-16

    • DOI

      10.5584/jiomics.v8i3.270

    • Related Report
      2018 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Andean cutaneous leishmaniasis (Andean-CL, uta) in Peru and Ecuador: the causative Leishmania parasites and clinico-epidemiological features2018

    • Author(s)
      Hashiguchi Yoshihisa、Gomez Eduardo A.L.、C?ceres Abraham G.、Velez Lenin N.、Villegas Nancy V.、Hashiguchi Kazue、Mimori Tatsuyuki、Uezato Hiroshi、Kato Hirotomo
    • Journal Title

      Acta Trop

      Volume: 177 Pages: 135-145

    • DOI

      10.1016/j.actatropica.2017.09.028

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Andean cutaneous leishmaniasis (Andean-CL, uta) in Peru and Ecuador: the vector Lutzomyia sand flies and reservoir mammals2018

    • Author(s)
      Hashiguchi Yoshihisa、Gomez L. Eduardo A.、C?ceres Abraham G.、Velez Lenin N.、Villegas Nancy V.、Hashiguchi Kazue、Mimori Tatsuyuki、Uezato Hiroshi、Kato Hirotomo
    • Journal Title

      Acta Trop

      Volume: 178 Pages: 264-275

    • DOI

      10.1016/j.actatropica.2017.12.008

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] An outbreak of Leishmania major from an endemic to a non-endemic region posed a public health threat in Iraq from 2014-2017: Epidemiological, molecular and phylogenetic studies2018

    • Author(s)
      Al-Bajalan Mariwan M. M.、Al-Jaf Sirwan M. A.、Niranji Sherko S.、Abdulkareem Dler R.、Al-Kayali Khudhair K.、Kato Hirotomo
    • Journal Title

      PLoS Negl Trop Dis

      Volume: 12 Issue: 3 Pages: e0006255-e0006255

    • DOI

      10.1371/journal.pntd.0006255

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comparison of Recombinant Proteins of Kinesin 39, Heat Shock Protein 70, Heat Shock Protein 83, and Glycoprotein 63 for Antibody Detection of Leishmania martiniquensis Infection2017

    • Author(s)
      Siripattanapipong Suradej、Kato Hirotomo、Tan-ariya Peerapan、Mungthin Mathirut、Leelayoova Saovanee
    • Journal Title

      J Eukaryot Microbiol

      Volume: 64 Issue: 6 Pages: 820-828

    • DOI

      10.1111/jeu.12415

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Salivary gland transcripts of the kissing bug, Panstrongylus chinai , a vector of Chagas disease2017

    • Author(s)
      Kato Hirotomo、Jochim Ryan C.、Gomez Eduardo A.、Tsunekawa Shunsuke、Valenzuela Jesus G.、Hashiguchi Yoshihisa
    • Journal Title

      Acta Trop

      Volume: 174 Pages: 122-129

    • DOI

      10.1016/j.actatropica.2017.06.022

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Salivary lipocalin family proteins from Panstrongylus chinai , a vector of Chagas disease2017

    • Author(s)
      Kato Hirotomo、Jochim Ryan C.、Gomez Eduardo A.、Tsunekawa Shunsuke、Valenzuela Jesus G.、Hashiguchi Yoshihisa
    • Journal Title

      Data Brief

      Volume: 15 Pages: 272-280

    • DOI

      10.1016/j.dib.2017.09.039

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of loop-mediated isothermal amplification (LAMP) assay combined with malachite green as a rapid screening test for Candidatus Mycoplasma haemominutum infection in cats.2017

    • Author(s)
      Tedlongthong S, Viseshakul N, Kato H, Areekit S, Santiwatanakul S, Chansiri K
    • Journal Title

      ScienceAsia

      Volume: 43 Issue: 6 Pages: 354-361

    • DOI

      10.2306/scienceasia1513-1874.2017.43.354

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] First identification of L. major in a dog in an endemic area of human cutaneous leishmaniasis in Iraq: molecular and phylogenetic studies2017

    • Author(s)
      Al-Bajalan Mariwan M. M.、Niranji Sherko S.、Al-Jaf Sirwan M. A.、Kato Hirotomo
    • Journal Title

      Parasitol Res

      Volume: 117 Issue: 2 Pages: 585-590

    • DOI

      10.1007/s00436-017-5704-7

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] リーシュマニア症2017

    • Author(s)
      加藤大智
    • Journal Title

      小児科臨床

      Volume: 70 Pages: 2272-2282

    • Related Report
      2017 Annual Research Report
  • [Presentation] Leishmaniac: Field to Lab & Lab to Field2024

    • Author(s)
      加藤大智
    • Organizer
      第93回日本寄生虫学会合同大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 医学部卒業5-16年後の医動物疾患の記憶と経験2024

    • Author(s)
      松岡裕之、加藤大智
    • Organizer
      第93回日本寄生虫学会合同大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ハマダラカにおいてdoublesex遺伝子の雄型産物は唾液腺の発達を抑制する2024

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      応用動物昆虫学会・昆虫学会 合同大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] サシチョウバエLutzomyia ayacuchensisの唾液由来PpSP15/SL1ファミリータンパク質の機能解析2023

    • Author(s)
      川堀悟、関千里、水島大貴、Ahmed Tabbabi、山本大介、加藤大智
    • Organizer
      第75回日本衛生動物学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Doublesex雄型タンパク質を欠損したハマダラカ雄における発現変動遺伝子の解析2023

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      第74回日本衛生動物学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] キサンチンデヒドロゲナーゼ(XDH)は希少糖アロースのハマダラカ中腸におけるマラリア原虫の発達抑制機構に関与する2023

    • Author(s)
      水島大貴,山本大介,Tababbi Ahmed,新井明治,加藤大智
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] マラリア自動診断システムの開発 ― 感染ステージに応じた認識システムの開発 -2023

    • Author(s)
      上野香緒理、花房 昭彦、Shahrol Mohamaddan、高木基樹、早川 枝李、加藤 大智
    • Organizer
      第62回日本生体医工学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ナミニクバエによる爪甲下蠅蛆病2023

    • Author(s)
      宮田聡子、加藤大智
    • Organizer
      第39回日本臨床皮膚科医会総会・学術大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] サシチョウバエdoublesex遺伝子の構造および発現の解析2023

    • Author(s)
      山本大介、Ahmed Tabbabi、水島大貴、加藤大智
    • Organizer
      第59回日本節足動物発生学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ハマダラカから見出されたレジリンホモログはオスのジョンストン器官特異的に発現する2023

    • Author(s)
      大久保 さくら、山本 大介、Judith H Willis、外川 徹
    • Organizer
      第94回日本動物学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ラクトースはハマダラカに下痢様症状を引き起こす2023

    • Author(s)
      水島 大貴、山本 大介、加藤 大智
    • Organizer
      第82回日本寄生虫学会東日本支部会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Effects of host species on microbiota composition in sand flies2023

    • Author(s)
      加藤大智、Ahmed Tabbabi、水島大貴、山本大介
    • Organizer
      グローバルヘルス合同大会2023
    • Related Report
      2021 Annual Research Report
  • [Presentation] 希少糖D-アロースはハマダラカ中腸におけるマラリア原虫の発達を中腸細菌叢非依存的に阻害する2023

    • Author(s)
      水島大貴、山本大介、Ahmed Tabbabi、新井明治、加藤大智
    • Organizer
      グローバルヘルス合同大会2023
    • Related Report
      2021 Annual Research Report
  • [Presentation] Resilin homologs found in Anopheles mosquitos are cuticular proteins specific to Johnston’s organ2023

    • Author(s)
      Sakura Ohkubo, Daisuke Yamamoto, Judith H Willis, Toru Togawa
    • Organizer
      The 6th International Insect Hormone Workshop
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] リーシュマニア症:フィールドからラボへ、ラボからフィールドへ2023

    • Author(s)
      加藤大智
    • Organizer
      埼大先端ラボ第26回MiUワークショップ
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] サシチョウバエにおけるdoublesex遺伝子オルソログの同定と発現解析2023

    • Author(s)
      山本大介、Ahmed Tabbabi、水島大貴、加藤大智
    • Organizer
      第67回応用動物昆虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ唾液物質 HlSG-g22 様遺伝子ノックダウンマダニの刺咬部位における炎症反応の病理学的評価2023

    • Author(s)
      佐々木 紗己、川田 逸人、小池 優貴、佐々木 萌可、中島 政斗、上松 史尚、松田 洋志郎、三角 修斗、 Kofi Dadzie Kwofie, Danielle Ladzekpo, Meryem Behri、 井上 貴裕、神保 恵、三上 房子、久保 誠、朽津 有紀、長塩亮、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第92回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ刺咬部位に集積した免疫細胞に関する病理学的解析2023

    • Author(s)
      小池 優貴、川田 逸人、佐々木 紗己、佐々木 萌可、中島 政斗、Kofi Dadzie Kwofie, Danielle Ladzekpo、Meriem Behr、井上 貴裕、神保 恵、三上 房子、久保 誠、朽津 有紀、長塩 亮、山本 大介、加藤 大智、辻尚利、八田 岳士
    • Organizer
      第92回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ペルー共和国北部アンデス地域におけるリーシュマニア症のベクター調査2022

    • Author(s)
      加藤大智、久保 誠、Abraham G. Caceres
    • Organizer
      第74回日本衛生動物学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ吸血必須因子 HlSG-g22は VE-cadhelinを介して血管透過性を亢進する2022

    • Author(s)
      川田逸人、小池優貴、佐々木紗己、朽津有紀、関口智也、佐々木萌可、中島政斗、山本大介、加藤大智、久保 誠、長塩 亮、辻 尚利、八田岳士
    • Organizer
      第74回日本衛生動物学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] キサンチンデヒドロゲナーゼ(XDH)は希少糖アロースのハマダラカ中腸におけるマラリア原虫の発達抑制機構に関与する2022

    • Author(s)
      水島大貴,山本大介,Tababbi Ahmed,新井明治,加藤大智
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] エクアドルに分布するリーシュマニア原虫の核遺伝子とキネトプラスト遺伝子の比較解析2022

    • Author(s)
      加藤大智、Eduardo A. Gomez、関千里、Ahmed Tabbabi、山本大介、橋口義久
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカにおけるアミノペプチダーゼN様遺伝子のノックアウト解析2022

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ唾液中に含まれる免疫抑制物質の探索2022

    • Author(s)
      佐々木 萌可、川田 逸人、小池 優貴、関口 智也、佐々木 紗己、中島 政斗、Emmanuel Pacia Hernandez, Kofi Dadzie Kwofie、Danielle Ladzekpo、井上 貴裕、神保 恵、三上 房子、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ唾液物質 HlSG-g22 の血管内皮細胞に及ぼす影響2022

    • Author(s)
      佐々木 紗己、川田 逸人、小池 優貴、関口 智也、佐々木 萌可、中島 政斗、Emmanuel Pacia Hernandez、Kofi Dadzie Kwofie、Danielle Ladzekpo、井上 貴裕、神保 恵、三上 房子、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ刺咬部位の病理学的解析2022

    • Author(s)
      小池 優貴、川田 逸人、朽津 有紀、佐々木 紗己、佐々木 萌可、中島 政斗、関口 智也、Emmanuel Pacia Hernandez、Kofi Dadzie Kwofie、Danielle Ladzekpo、井上 貴裕、神保 恵、三上 房子、久保 誠、長塩 亮、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第91回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マラリア自動診断システムの開発- 自動トリミングによる判定効率の向上 -2022

    • Author(s)
      上野香緒理、花房 昭彦、Shahrol Mohamaddan、高木基樹、早川 枝李、加藤 大智
    • Organizer
      第61回日本生体医工学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカにおける性分化遺伝子doublesexの雄型産物の機能解析2022

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      第93回日本動物学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ムシを運ぶムシ リーシュマニア症のベクター調査2022

    • Author(s)
      加藤大智
    • Organizer
      第81回日本寄生虫学会東日本支部大会・日本共生生物学会第6回大会 合同大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] マダニ唾液腺由来 HlSG-g22 様分子の刺咬部位における役割2022

    • Author(s)
      佐々木 紗己、川田 逸人、小池 優貴、佐々木 萌可、中島 政斗、上松 史尚、井上 貴裕、神保 恵、三上 房子、Kofi Dadzie Kwofie、Danielle Ladzekpo、Meryem Behri、朽津 有紀、長塩 亮、久保 誠、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第81回日本寄生虫学会東日本支部大会・日本共生生物学会第6回大会 合同大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ペルー共和国北部アンデス地域におけるリーシュマニア症のベクター調査2022

    • Author(s)
      加藤大智、久保誠、Abraham Caceres
    • Organizer
      第63回日本熱帯医学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Comparative Analysis of Bacterial Communities in Lutzomyia ayacuchensis Populations with Different Vector Competence to Leishmania Parasites in Ecuador and Peru2022

    • Author(s)
      Ahmed Tabbabi, Shinya Watanabe, Daiki Mizushima, Abraham G. Caceres, Eduardo A Gomez, Daisuke S. Yamamoto, Longzhu Cui, Yoshihisa Hashiguchi and Hirotomo Kato
    • Organizer
      第63回日本熱帯医学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Insight into the embryogenesis of the parthenogenetic ixodid tick, Haemaphysalis longicornis based on a classic transcriptomic study2021

    • Author(s)
      Kofi Dadzie Kwofie, Emmanuel Pacia Hernandez, Hayato Kawada, Yuki Koike, Sana Sasaki, Samuel Dadzie, Danielle Ladzekpo, Tomoya Sekiguchi, Fusako Mikami, Makoto Matsubayashi, Daisuke Yamamoto, Hirotomo Kato, Shiroh Iwanaga, Naotoshi Tsuji, Takeshi Hatta
    • Organizer
      第90回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Promoter analysis of elongation factor 1-alpha (EF1α) derived from Haemaphysalis longicornis2021

    • Author(s)
      Emmanuel Pacia Hernandez, Hayato Kawada, Yuki Koike, Sana Sasaki, Kofi Dadzie Kwofie, Danielle Ladzekpo, Tomoya Sekiguchi, Fusako Mikami, Daisuke Yamamoto, Hirotomo Kato, Makoto Matsubayashi, Tetsuya Tanaka, Naotoshi Tsuji, Takeshi Hatta
    • Organizer
      第90回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] フタトゲチマダニにおける吸血部位微小環境の病理学的解析2021

    • Author(s)
      小池 優貴、川田 逸人、佐々木 紗己、横井 愛香、朽津 有紀、長塩 亮、久保 誠、山本 大介、加藤 大智、辻 尚利、八田 岳士
    • Organizer
      第90回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカの中腸環境を改変する糖類のスクリーニング2021

    • Author(s)
      水島 大貴、Ahmed Tabbabi、山本 大介、新井 明治、加藤 大智
    • Organizer
      第90回日本寄生虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ステフェンスハマダラカ雌の生殖におけるアミノペプチダーゼN様遺伝子の機能解析2021

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      日本節足動物発生学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Comparative Analysis of Bacterial Communities in Lutzomyia ayacuchensis Populations with Different Vector Competence to Leishmania Parasites in Ecuador and Peru2021

    • Author(s)
      Tabbabi A, Watanabe S, Mizushima D, C?ceres AG, Gomez EA, Yamamoto DS, Cui L, Hashiguchi Y, Kato H.
    • Organizer
      JMUシンポジウム
    • Related Report
      2020 Annual Research Report
  • [Presentation] A rare sugar, allose, inhibit malaria parasite development by modulating mosquito gut environment2021

    • Author(s)
      Mizushima D, Tabbabi A, Yamamoto DS, Arai M, Kato H
    • Organizer
      JMUシンポジウム
    • Related Report
      2020 Annual Research Report
  • [Presentation] フィールドからラボへ、ラボからフィールドへ:リーシュマニア症の疫学調査研究2021

    • Author(s)
      加藤大智
    • Organizer
      第80回日本寄生虫学会 東日本支部大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] マダニ唾液中に含まれる細胞融解因子2021

    • Author(s)
      小池 優貴、川田 逸人、佐々木 紗己、朽津 有紀、横井 愛香、関口 智也、佐々木 萌可、中島 政斗、三上 房子、長塩 亮、久保 誠、加藤 大智、山本 大介、辻 尚利、 八田 岳士
    • Organizer
      第80回日本寄生虫学会 東日本支部大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 南米アンデス地域で異なるリーシュマニア原虫媒介能をもつサシチョウバエLutzomyia ayacuchensisの遺伝子多型解析および腸内細菌叢の比較解析2021

    • Author(s)
      Tabbabi, A.、水島大貴、Caceres, A.G.、Gomez, E.A.、山本大介、橋口義久、加藤大智
    • Organizer
      第72回日本衛生動物学会 東日本支部大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカAnopheles stephensiの中腸で発現するアミノペプチダーゼN様遺伝子apnlの遺伝子ノックアウト2021

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      第72回日本衛生動物学会 東日本支部大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マダニ刺咬部位における唾液分子HlSG-g22の役割.2021

    • Author(s)
      川田 逸人、小池 優貴、佐々木 紗己、朽津 有紀、横井 愛香、関口 智也、三上 房子、Emmanuel Pacia Hernandez、 Kofi Dadzie Kwofie、Danielle Ladzekpo、山本 大介、加藤 大智、長塩 亮、辻 尚利、八田 岳士
    • Organizer
      第72回日本衛生動物学会 東日本支部大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカAnopheles stephensiにおけるdoublesex遺伝子雄型産物のノックアウト解析2021

    • Author(s)
      山本大介、水島大貴、加藤大智
    • Organizer
      第66回応用動物昆虫学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Leishmaniasis: field-to-lab & lab-to-field2021

    • Author(s)
      加藤大智
    • Organizer
      JSPS 研究拠点形成事業 寄生虫学・熱帯医学/環境衛生学 合同セミナー
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] アジアに分布する吸血性サシガメTriatoma rubrofasciataの唾液腺トランスクリプトーム解析2020

    • Author(s)
      加藤大智、水島大貴、Ahmed Tabbabi、山本大介、角田隆、Le Trung Kien
    • Organizer
      第72回 日本衛生動物学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ハマダラカにおける性分化遺伝子の制御を受ける中腸遺伝子の解析2020

    • Author(s)
      山本大介、炭谷めぐみ、加藤大智
    • Organizer
      第72回 日本衛生動物学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 赤内期熱帯熱マラリア原虫のコレステロールの取り込み機構と膜のリサイクリングについての解明2020

    • Author(s)
      早川枝李、加藤大智、Nardone Glenn、 臼倉治郎
    • Organizer
      第89回日本寄生虫学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] リーシュマニア症診断のための高感度な赤血球凝集反応の開2020

    • Author(s)
      伊藤 誠、Lalindi De Silva、Upeksha Rathnapala、Thishan C. Yahathugoda、高木秀和、長岡史晃、加藤大智
    • Organizer
      第89回日本寄生虫学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] PCR-RFLP法を用いたエクアドルに分布するリーシュマニア原虫種の同定と、それによって明らかになった種間交雑株の分布2020

    • Author(s)
      加藤大智、Eduardo A. Gomez、関千里、Ahmed Tabbabi、山本大介、橋口義久
    • Organizer
      第89回日本寄生虫学会大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] The diagnostic capabilities of an in-house ELISA method in the diagnosis of cutaneous leishmaniasis caused by Leishmania donovani in Hambantota district, Sri Lanka2020

    • Author(s)
      De Silva NL, De Silva VNH, Deerasinghe ATH, Kato H, Itoh M, Takagi H, Weerasooriya MV and Yahathugoda TC
    • Organizer
      69th ASTMH Annual Meeting
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 新大陸のサシチョウバエについて2020

    • Author(s)
      加藤大智
    • Organizer
      第35回有生研フォーラム
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 性分化遺伝子の制御を受けるハマダラカ血液消化関連遺伝子の探索2019

    • Author(s)
      山本大介、炭谷めぐみ、加藤大智
    • Organizer
      第55回日本節足動物発生学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] サシチョウバエ唾液の生理活性2019

    • Author(s)
      加藤大智
    • Organizer
      第71回日本衛生動物学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Development of Malaria Automatic Diagnosis System. -Evaluation by Appling the Deep Learning Method-2019

    • Author(s)
      Waon Haraguchi, Akihiko Hanafusa, Eri Hayakawa, Hirotomo Kato
    • Organizer
      2nd Americas Conference on Medical Imaging and Clinical Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ハマダラカ雌におけるdoublesex欠損の吸血・血液消化への影響2019

    • Author(s)
      山本大介、炭谷めぐみ、加藤大智
    • Organizer
      第90回日本動物学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Observation of cholesterol sorting in P. falciparum-erythrocytes by 3D label-free Holotomographic imaging2019

    • Author(s)
      Eri H. Hayakawa , Glenn Nardone , Kentaro Yamaguchi , Hiroyuki Matsuoka, Hirotomo Kato, Masahiro Mori, Jiro Usukura
    • Organizer
      American Society for Cell Biology (ASCB) 58th Annual Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マラリア自動診断システムの開発 ―ディープラーニングによる適用評価―2019

    • Author(s)
      原口和音,花房昭彦,早川枝李,加藤大智
    • Organizer
      第28回日本コンピュータ外科学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] PCR-RFLP法を用いたエクアドルに分布するリーシュマニア原虫種の同定2019

    • Author(s)
      加藤大智、Eduardo A. Gomez、関千里、Ahmed Tabbabi、山本大介、橋口義久
    • Organizer
      第79回日本寄生虫学会東日本支部大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ペルー共和国におけるリーシュマニア原虫の地理的分布2019

    • Author(s)
      加藤大智、Abraham G. Caceres、関千里、久保誠、Ahmed Tabbabi、山本大介、橋口義久
    • Organizer
      第60回日本熱帯医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Trypanosoma cruzi媒介サシガメPanstrongylus chinaiの唾液腺遺伝子転写産物の解析2018

    • Author(s)
      加藤大智、Ryan C. Jochim、Eduardo A. Gomez、Jesus G. Valenzuela、橋口義久
    • Organizer
      第87回日本寄生虫学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 熱帯熱マラリア原虫と肝細胞の共培養系におけるコレステロール輸送の薬剤感受性に関する解析2018

    • Author(s)
      早川枝李、加藤大智、松岡裕之、森雅博
    • Organizer
      第87回日本寄生虫学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ハマダラカにおけるdoublesex遺伝子ノックアウト2018

    • Author(s)
      山本大介、炭谷めぐみ、畠山正統、加藤大智
    • Organizer
      第62回応用動物昆虫学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 精巣における細胞死誘導系を導入したハマダラカの解析2017

    • Author(s)
      山本大介、炭谷めぐみ、笠嶋克巳、瀬筒秀樹、松岡裕之、加藤大智
    • Organizer
      第69回 日本衛生動物学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ペルー共和国で流行するハイブリッド型リーシュマニア原虫のベクター調査2017

    • Author(s)
      加藤大智、アブラハム・カセレス、橋口義久
    • Organizer
      第69回 日本衛生動物学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 細胞死誘導法によるハマダラカの雄不妊化の効果2017

    • Author(s)
      山本大介、炭谷めぐみ、笠嶋克巳、瀬筒秀樹、松岡裕之、加藤大智
    • Organizer
      第53回 節足動物発生学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] エクアドル共和国におけるリーシュマニア症の広域分子疫学調査2017

    • Author(s)
      加藤大智、Eduardo A. Gomez、Lenin Velez、三森龍之、橋口義久
    • Organizer
      第86回日本寄生虫学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Field-applicable biosensing of cutaneous leishmaniasis species by rapid Recombinase Polymerase Amplification and Temperature Gradient Gel Electrophoresis2017

    • Author(s)
      Himankshi Rathore, Hirotomo Kato, Yuzuru Takamura, Manish Biyani
    • Organizer
      The Ninth International Conference on Molecular Electronics and Bioelectronics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A prospective lipid import mechanism of Plasmodium falciparum in erythrocytes stages2017

    • Author(s)
      Eri H. Hayakawa, Hirotomo Kato, Hiroyuki Matsuoka, Masahiro Mori
    • Organizer
      ASCB 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Book] Mucosal Vaccine for Parasitic Infection, In: Mucosal Vaccines: Innovation for Preventing Infectious Diseases, Pascual DW, Kiyono H. (Ed)2019

    • Author(s)
      Hirotomo Kato
    • Total Pages
      14
    • Publisher
      Elsevier
    • Related Report
      2019 Annual Research Report
  • [Remarks] http://www.jichi.ac.jp/idoubutsu/indexTJ2.html

    • Related Report
      2018 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2025-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi