| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2020: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2019: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
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| Outline of Final Research Achievements |
To clarify the neural mechanisms for complex visual hallucinations that the patients with Lewy bodies experience, we studied two types of neural networks. Model 1 consisting of three modules of visual cortex, prefrontal cortex and temporal cortex exhibited hallucinatory images, due to the excess increase of synaptic strength after the reduction of synaptic connections between visual cortex and prefrontal cortex. Accordingly, model 2 showed chaotically itinerant transitions between veridical and hallucinatory perceptions after the reduction of synaptic connections between either two of three modules.
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