• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Involvement of motor learning in the recovery from functional deficits after stroke

Research Project

Project/Area Number 17H02128
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionWaseda University

Principal Investigator

Osu Rieko  早稲田大学, 人間科学学術院, 教授 (60374112)

Co-Investigator(Kenkyū-buntansha) 大高 洋平  藤田医科大学, 医学部, 教授 (00317257)
井澤 淳  筑波大学, システム情報系, 准教授 (20582349)
Project Period (FY) 2017-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2021: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Keywords脳卒中 / 意思決定 / 非侵襲脳刺激 / tDCS / リハビリテーション / 計算神経科学 / 脳神経疾患 / ニューロリハビリテーション / 実験系心理学
Outline of Final Research Achievements

Rehabilitation restores the function of the paretic hand/arm caused by stroke to a certain degree. However, patients often lose the recovered function because they do not prefer to use the paretic hand in daily life. This learned non-use of the paretic hand is a significant factor preventing functional recovery. Therefore, we examined how we can intervene in the use of the paretic hand rather than the function. Experimental results with healthy participants revealed that transcranial direct current stimulation of the posterior parietal cortex, which is thought to be involved in hand choice, can add a bias to hand choice without the participant's awareness. Specifically, when a cathode was placed on the left posterior parietal cortex to suppress brain activity, and an anode was placed on the right posterior parietal cortex to activate brain activity, the left-hand choice probability increased, and the reaction time became shorter.

Academic Significance and Societal Importance of the Research Achievements

片麻痺は脳卒中後の代表的な後遺症の一つです。退院後の生活の中で、健常側をばかりを使ってしまう「麻痺手の不使用」は、回復を阻害する要因とされています。しかし、回復期リハビリテーション病棟においては、「機能」の訓練をする一方、「使用」に対する訓練はこれまで実施されてきていませんでした。「使用」に介入することで、回復した機能を再び失ってしまうのを防いで機能を維持することができれば、リハビリテーションの効率を大きく改善し、患者のQOLを向上させると共に、医療費の削減にもつながることが期待できます。

Report

(5 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (13 results)

All 2021 2020 2019 2018

All Journal Article (6 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 5 results) Presentation (7 results) (of which Int'l Joint Research: 2 results,  Invited: 3 results)

  • [Journal Article] Transcranial direct current stimulation of the posterior parietal cortex biases human hand choice2021

    • Author(s)
      Hirayama Kento、Koga Takayuki、Takahashi Toru、Osu Rieko
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 204-204

    • DOI

      10.1038/s41598-020-80611-8

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] アスリートの外傷と運動学習能力の関係に関する予備的検討2021

    • Author(s)
      大須理英子、早川梨香子、古賀敬之、平山健人、江川陽介
    • Journal Title

      人間科学研究

      Volume: 33-34 Pages: 249-255

    • NAID

      120007030531

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hierarchical motor adaptations negotiate failures during force field learning2021

    • Author(s)
      Ikegami Tsuyoshi、Ganesh Gowrishankar、Gibo Tricia L.、Yoshioka Toshinori、Osu Rieko、Kawato Mitsuo
    • Journal Title

      PLOS Computational Biology

      Volume: 17 Issue: 4 Pages: 1008481-1008481

    • DOI

      10.1371/journal.pcbi.1008481

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Plastic frontal pole cortex structure related to individual persistence for goal achievement2020

    • Author(s)
      Chihiro Hosoda, Satoshi Tsujimoto, Masaru Tatekawa, Manabu Honda, Rieko Osu, Takashi Hanakawa
    • Journal Title

      communications biology

      Volume: 0 Issue: 1 Pages: 0-0

    • DOI

      10.1038/s42003-020-0930-4

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Revealing Relationships Among Cognitive Functions Using Functional Connectivity and a Large-Scale Meta-Analysis Database2020

    • Author(s)
      Kurashige Hiroki、Kaneko Jun、Yamashita Yuichi、Osu Rieko、Otaka Yohei、Hanakawa Takashi、Honda Manabu、Kawabata Hideaki
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 13 Pages: 457-457

    • DOI

      10.3389/fnhum.2019.00457

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neuroanatomical Basis of Individuality in Muscle Tuning Function: Neural Correlates of Muscle Tuning2019

    • Author(s)
      Kahori Kita,Rieko Osu,Chihiro Hosoda,Manabu Honda,Takashi Hanakawa,Jun Izawa
    • Journal Title

      Frontiers in Behavioral Neuroscience

      Volume: 13:28 Pages: 00028-00028

    • DOI

      10.3389/fnbeh.2019.00028

    • NAID

      120007127915

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Transcranial Direct Current Stimulation on Posterior Parietal Cortex Biases Human Hand Choice2020

    • Author(s)
      Kento Hirayama, Takayuki Koga, Rieko Osu
    • Organizer
      The 2nd International Symposium on Applied Abstraction and Integrated Design
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 後頭頂葉への経頭蓋直流電気刺激が上肢選択意思決定に与える影響2019

    • Author(s)
      平山健人, 古賀敬之, 大須理英子
    • Organizer
      第24回基礎理学療法学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 後頭頂葉への直流電気刺激が上肢選択意思決定の選択率・反応時間に与える影響2019

    • Author(s)
      平山健人, 古賀敬之, 大須理英子
    • Organizer
      第13回モーターコントロール研究会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] リハビリテーション医学への計算神経科学の導入例2019

    • Author(s)
      大須理英子
    • Organizer
      日本リハビリテーション医学会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Human motor control/learning and neurorehabilitation2019

    • Author(s)
      Rieko Osu
    • Organizer
      dynamic-neuronal-circuits-and-motor-behavior workshop
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] リハビリテーション医学と計算神経科学の融合の先にあるもの2019

    • Author(s)
      大須理英子
    • Organizer
      高崎健康福祉大学 公開講座
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 脳卒中回復期における小脳灰白質の容積変化2018

    • Author(s)
      大須理英子、森田とわ、田中悟志、磯谷悠子、倉重宏樹、近藤国嗣、大高洋平、荒牧勇
    • Organizer
      日本心理学会
    • Related Report
      2018 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2023-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi