Cognitive neuroscientific approach to gait and positive thinking
| Project/Area Number |
17H02173
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied health science
|
|---|
| Research Institution | National Institutes for Quantum and Radiological Science and Technology |
|---|
Principal Investigator |
Makiko Yamada 国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, グループリーダー(定常) (50557444)
|
|---|
| Project Period (FY) |
2017-04-01 – 2020-03-31
|
| Project Status |
Completed (Fiscal Year 2019)
|
| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
|
|---|
| Keywords | Positive illusion / Cognitive bias / Gait / Depression / EEG / 認知神経科学 / 認知科学 |
|---|
| Outline of Final Research Achievements |
Using item response theory, we have estimated the optimistic prediction of future event to develop a quantitative measure of positive thinking. We then performed the correlation analysis and found that the estimated optimistic prediction was significantly correlated with BHS and BDI-II which indicated the validity of the scale.
Relationship between gait and positive thinking: Analysis of motion capture data during spontaneous walking revealed that participants who walked with large head-pelvis tilts (bending forward) estimated the likelihood of a negative event to be high.
Relationship between gait and brain activity: Analysis of frontal α asymmetry (FAA) during walking revealed that the gait control shifted FAA to the right dominant and increased the optimistic future prediction.
|
| Academic Significance and Societal Importance of the Research Achievements |
本研究によって、前向き思考と姿勢制御の関係が脳機能を介して解明されることで、こころの健康を支える身体―思考―脳機能相互作用機序の理解が深まり、うつ病患者や運動障害を呈するパーキンソン病などの病態メカニズム解明や、歩様をターゲットとした新たな非薬物治療戦略開発など、医学研究への発展が期待される。
|
Report
(4 results)
Research Products
(28 results)
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] Anatomical relationships between serotonin 5-HT2A and dopamine D2 receptors in living human brain.2017
Author(s)
Ishii T, Kimura Y, Ichise M, Takahata K, Kitamura S, Moriguchi S, Kubota M, Zhang MR, Yamada M, Higuchi M, Okubo Y, Suhara T.
-
Journal Title
PLoS One.
Volume: 12
Issue: 12
Pages: e0189318-e0189318
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
[Journal Article] Indications of success: Strategies for utilizing neuroimaging biomarkers in CNS drug discovery and development: CINP/JSNP working group report.2017
Author(s)
Suhara T, Chaki S, Kimura H, Furusawa M, Matsumoto M, Ogura H, Negishi T, Saijo T, Higuchi M, Omura T, Watanabe R, Miyoshi S, Nakatani N, Yamamoto N, Liou SY, Takado Y, Maeda J, Okamoto Y, Okubo Y, Yamada M, Ito H, Walton NM, et al.
-
Journal Title
Int J Neuropsychopharmacol.
Volume: 20(4)
Pages: 285-294
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
