Developing a novel method of optically detected magnetic resonance measurement method for pharmaceutical application

• Project/Area Number: 17H02751
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Nanobioscience
• Research Institution: Waseda University
• Principal Investigator: Tanii Takashi 早稲田大学, 理工学術院, 教授 (20339708)
• Co-Investigator(Kenkyū-buntansha): 磯谷 順一 筑波大学, 数理物質系, 研究員 (60011756) ; 星野 忠次 千葉大学, 大学院薬学研究院, 准教授 (90257220)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000); Fiscal Year 2019: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000); Fiscal Year 2017: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
• Keywords: ダイヤモンド / NVセンター / ナノNMR / 創薬応用 / ダイヤモンドNVセンタ / 1分子計測 / ＮＶセンタ / ＮＭＲ / １分子計測 / NVセンタ / ナノＮＭＲ / 創薬スクリーニング / ダイヤモンド中ＮＶセンタ / 一分子計測

Outline of Final Research Achievements

We proposed a novel self-align process for the fabrication of nano-reservoir with a single NV centers at the bottom by combination of electron beam lithography, ion implantation and dry etching, and explored the feasibility of nano-NMR for the drag discovery in pharmaceutical application using the nano-reservoir.

Academic Significance and Societal Importance of the Research Achievements

創薬応用には薬物と候補タンパク質との親和性を１分子レベルで網羅的に定量評価できる計測手法が必要と考えられる。ダイヤモンド中の窒素と空孔とからなる原子レベルのセンサーがこの目的を達成できる性能を発現できるようにダイヤモンド表面に微細加工を施し、その計測系の性能評価を実行した。

Research Products

• [Int'l Joint Research] Ulm Univ.(ドイツ)
• [Int'l Joint Research] CNR(イタリア)
• [Int'l Joint Research] Ulm University(ドイツ)
• [Int'l Joint Research] CNR/Politecnico di Milano(イタリア)
• [Int'l Joint Research] Ulm University(ドイツ)
• [Int'l Joint Research] CNR/Politecnico di Milano(イタリア)
• [Journal Article] Triple nitrogen-vacancy centre fabrication by C5N4Hn ion implantation (2019)
  • Author(s): Moriyoshi Haruyama, Shinobu Onoda, Taisei Higuchi, Wataru Kada, Atsuya Chiba, Yoshimi Hirano, Tokuyuki Teraji, Ryuji Igarashi, Sora Kawai, Hiroshi Kawarada, Yu Ishii, Ryosuke Fukuda, Takashi Tanii, Junichi Isoya, Takeshi Ohshima, Osamu Hanaizumi
  • Journal Title: Nature communications Volume: 10 Pages: 2664-2664
  • Peer Reviewed / Open Access
• [Journal Article] Microwave-Free Vector Magnetometry with Nitrogen-Vacancy Centers along a Single Axis in Diamond (2019)
  • Author(s): Huijie Zheng, Zhiyin Sun, Georgios Chatzidrosos, Chen Zhang, Kazuo Nakamura, Hitoshi Sumiya, Takeshi Ohshima, Junichi Isoya, Joerg Wrachtrup, Arne Wickenbrock, Dmitry Budker
  • Journal Title: Phys. Rev. Applied. Volume: 13 Issue: 4 Pages: 4904-4910
  • DOI: 10.1103/physrevapplied.13.044023
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Nitrogen-Terminated Diamond Surface for Nanoscale NMR by Shallow Nitrogen-Vacancy Centers (2019)
  • Author(s): S. Kawai, H. Yamano, T. Sonoda, K. Kato, J. Buendia, T. Kageura, R. Fukuda, T. Okada, T. Tanii, T. Higuchi, M. Haruyama, K. Yamada, S. Onoda, T. Ohshima, W. Kada, O. Hanaizumi, A. Stacey, T. Teraji, S. Kono, J. Isoya, H. Kawarada
  • Journal Title: J. Phys. Chem. C Volume: 123 Issue: 6 Pages: 3594-3604
  • DOI: 10.1021/acs.jpcc.8b11274
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Room Temperature Resonant Photocurrent in an Erbium Low-doped Silicon Transistor at Telecom Wavelength (2019)
  • Author(s): M. Celebrano, L. Ghirardini, M. FInazzi, G. Ferrari, Y. Chiba, A. Abdelghafar, M. Yano, T. Shinada, T. Tanii, E. Prati
  • Journal Title: Nanomaterials Volume: 9 Issue: 3 Pages: 416-416
  • DOI: 10.3390/nano9030416
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Compact integrated magnetometer based on nitrogen-vacancy centres in diamond (2019)
  • Author(s): F. M. Stuerner, A. Brenneis, J. Kassel, U. Wostradowski, R. Roelver, T. Fuchs, K. Nakamura, H. Sumiya, S. Onoda, J. Isoya, F. Jelezko
  • Journal Title: Diamond and Related Materials Volume: 93 Pages: 59-65
  • DOI: 10.1016/j.diamond.2019.01.008
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Lithographically engineered shallow nitrogen-vacancy centers in diamond for external nuclear spin sensing (2018)
  • Author(s): Fukuda Ryosuke、Balasubramanian Priyadharshini、Higashimata Itaru、Koike Godai、Okada Takuma、Kagami Risa、Teraji Tokuyuki、Onoda Shinobu、Haruyama Moriyoshi、Yamada Keisuke、Inaba Masafumi、Yamano Hayate、Jelezko Fedor、Tanii Takashi、Isoya Junichi et al.
  • Journal Title: New Journal of Physics Volume: 20 Issue: 8 Pages: 083029-083029
  • DOI: 10.1088/1367-2630/aad997
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] GeVn complexes for silicon-based room-temperature single-atom nanoelectronics (2018)
  • Author(s): Simona Achilli, Nicola Manini, Giovanni Onida, Takahiro Shinada, Takashi Tanii, and Enrico Prati
  • Journal Title: Scientific Report Volume: 8 Issue: 1 Pages: 180054-180054
  • DOI: 10.1038/s41598-018-36441-w
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Impact of modular organization on dynamical richness in cortical networks (2018)
  • Author(s): H. Yamamoto, S. Moriya, K. Ide, T. Hayakawa, H. Akima, S. Sato, S. Kubota, T. Tanii, M. Niwano, S. Teller, J. Soriano, A. Hirano-Iwata
  • Journal Title: Science Advances Volume: 4 Issue: 11
  • DOI: 10.1126/sciadv.aau4914
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Superradiant emission from colour centres in diamond (2018)
  • Author(s): Andreas Angerer, Kirill Streltsov, Thomas Astner, Stefan Putz, Hitoshi Sumiya, Shinobu Onoda, Junichi Isoya, William J. Munro, Kae Nemoto, Jorg Schmiedmayer & Johannes Majer
  • Journal Title: Nature Physics Volume: 14 Issue: 12 Pages: 1168-1172
  • DOI: 10.1038/s41567-018-0269-7
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] In situ modification of cell-culture scaffolds by photocatalysis of visible-light-responsive TiO2 film (2018)
  • Author(s): Sho Kono, Kohei Furusawa, Atsushi Kurotobi, Kohei Hattori, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Journal Title: Japanese Journal of Applied Physics Volume: 57 Issue: 2 Pages: 027001-027001
  • DOI: 10.7567/jjap.57.027001
  • NAID: 130005974822
  • Peer Reviewed
• [Journal Article] Effect of a radical exposure nitridation surface on the charge stability of shallow nitrogen-vacancy centers in diamond (2017)
  • Author(s): T. Kageura, K. Kato, H. Yamano, E. Suaebah, M. Kajiya, S. Kawai, M. Inaba, T. Tanii, M. Haruyama, K. Yamada, S. Onoda, W. Kada, O. Hanaizumi, T. Teraji, J. Isoya, S. Kono, and H. Kawarada
  • Journal Title: Appl.Phys.Express Volume: 10 Issue: 5 Pages: 0555031-4
  • DOI: 10.7567/apex.10.055503
  • NAID: 210000135854
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Charge state stabilization of shallow nitrogen vacancy centers in diamond by oxygen surface modification (2017)
  • Author(s): H. Yamano, S. Kawai, K. Kato, T. Kageura, M. Inaba, T. Okada, I. Higashimata, M. Haruyama, T. Tanii, K. Yamada, S. Onoda, W. Kada, O. Hanaizumi, T. Teraji, J. Isoya, and H. Kawarada
  • Journal Title: Jpn. J. Appl. Phys. Volume: 56 Issue: 4S Pages: 04CK08-04CK08
  • DOI: 10.7567/jjap.56.04ck08
  • NAID: 210000147635
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Atom probe tomographic assessment of the distribution of germanium atoms implanted in a silicon matrix through nano-apertures (2017)
  • Author(s): Tu Y、Han B、Shimizu Y、Inoue K、Fukui Y、Yano M、Tanii T、Shinada T、Nagai Y
  • Journal Title: Nanotechnology Volume: 28 Issue: 38 Pages: 385301-385301
  • DOI: 10.1088/1361-6528/aa7f49
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Room-temperature 1.54 um photoluminescence from Er:Ox centers at extremely low concentration in silicon (2017)
  • Author(s): M. Celebrano, L. Ghirardini, M. Finazzi, Y. Shimizu, Y. Tu, K. Inoue, Y. Nagai, T. Shinada, Y. Chiba, A. Abderghafar, M. Yano, T. Tanii, E. Prati
  • Journal Title: Opt. Lett. 42 (2017) 3311 Volume: 42 Issue: 17 Pages: 3311-3314
  • DOI: 10.1364/ol.42.003311
  • Peer Reviewed / Int'l Joint Research
• [Presentation] 高分解能ナノ NMR に向けたダイヤモンドへの NV センターと微小容器の一括形成 (2020)
  • Author(s): 齋藤悠太、石井邑、川勝一斗、永岡希朗、畑雄貴、中村洸介、榎田尊昭、徐海州、薗田隆弘、立石哲也、金久京太郎、寺地徳之、小野田 忍、樋口泰成、山田圭介、大島武、品田高宏、川原田洋、加田渉、花泉修、磯谷順一、谷井孝至
  • Organizer: 第67回応用物理学会春季学術講演会
• [Presentation] 2針電極を用いた神経細胞刺激の応答計測とその理論解析 (2020)
  • Author(s): 服部 晃平, 石田 実穂子, 鞍掛 碧流, 今井 絢子, 橋本 拓弥, 佐藤 晃揮, 髙橋 穂乃歌, 小熊 奏一郎, 山本 英明, 平野 愛弓, 谷井 孝 至
  • Organizer: 第67回応用物理学会春季学術講演会
• [Presentation] 2針電極を用いた神経細胞刺激の応答計測とその理論解析 (2020)
  • Author(s): 鞍掛 碧流, 服部 晃平, 今井 絢子, 橋本 拓弥, 佐藤 晃揮, 髙橋 穂乃歌, 小熊 奏一郎, 石田 実穂子, 山本 英明, 平野 愛弓, 谷井 孝 至
  • Organizer: 第67回応用物理学会春季学術講演会
• [Presentation] An experimental study on the spontaneous firing of single isolated neurons in autaptic culture using micropatterned substrates (2020)
  • Author(s): Kouhei Hattori, Koki Sato, Honoka Takahashi, Soichiro Oguma, Mihoko Ishida, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: the 8th RIEC International Symposium on Brain Functions and Brain Computer
  • Int'l Joint Research
• [Presentation] Stimulation of micropatterned neurons with a pair of needles electrodes and the activity measurement (2020)
  • Author(s): Junko Imai, Hekiru Kurakake, Takuya Hashimoto, Kouhei Hattori, Koki Sato, Honoka Takahashi, Soichiro Oguma, Mihoko Ishida, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: the 8th RIEC International Symposium on Brain Functions and Brain Compu
  • Int'l Joint Research
• [Presentation] ワイドギャップ半導体を利用した量子センサ開発 (2019)
  • Author(s): 小野田忍、大島武、磯谷順一、寺地徳之、川原田洋、谷井孝至、加田渉、波多野睦子
  • Organizer: 電子デバイス研究会
  • Invited
• [Presentation] Synaptic plasticity in an isolated single autaptic neuron on a micropattern (2019)
  • Author(s): Akira Nakanishi, Kouhei Hattori, Takeshi Hayakawa, Mihoko Ishida, Hekiru Kurakake, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: 日本神経回路学会 第29回全国大会
• [Presentation] 2本針型刺激電極の試作とマイクロパターン上神経細胞回路への刺激導入に関する実行可能性評価 (2019)
  • Author(s): 服部 晃平、鞍掛 碧流、今井 絢子、橋本 拓弥、佐藤 晃揮、髙橋 穂乃歌、早川 岳志、山本 英明、平野 愛弓、谷井 孝至
  • Organizer: 第80回応用物理学会秋季学術講演会
• [Presentation] A computational study on the spontaneous firing pattern of single autaptic neurons - The contribution of AMPA and NMDA current - (2019)
  • Author(s): Mihoko Ishida, Kouhei Hattori, Akira Nakanishi, Takeshi Hayakawa, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: The 4th International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development
  • Int'l Joint Research
• [Presentation] An experimental study on the spontaneous firing of single isolated autaptic neurons using micropatterned substrates (2019)
  • Author(s): Honoka Takahashi, Koki Sato, Mihoko Ishida, Soichiro Oguma, Takeshi Hayakawa, Kouhei Hattori, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: The 4th International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development
  • Int'l Joint Research
• [Presentation] Self-align fabrication of nano-reservoir with NV center in diamond surface for nuclear magnetic resonance of small molecules (2019)
  • Author(s): Kazuto Kawakatsu, Yu Ishii, Yuki Hata, Yuta Saito, Kosuke Nakamura, Kirou Nagaoka, Takahiro Sonoda, Tetsuya, Tatsuishi, Tokuyuki Teraji, Shinobu Onoda, Taisei Higuchi, Keisuke Yamada, Takeshi Oshima, Takahiro Shinada, Hiroshi Kawarada, Wataru Kada, Osamu Hanaizumi, Junichi Isoya and Takashi Tanii
  • Organizer: 32nd International Microprocesses and Nanotechnology Conference
• [Presentation] MOSトランジスタへのErイオン注入と 1.5 μm帯光励起電流の計測 (2019)
  • Author(s): 藤本宇郁、魏啓楠, 鈴木雄大,清水康雄,井上耕治,永井康介, M.Celebrano,E.Prati, L.Ghirardini, M.Finazzi,品田高宏,谷井孝至
  • Organizer: 東北大学金属材料研究所付属量子エネルギー材料科学国際研究センター 2019年度大洗アルファ合同研究会
• [Presentation] Resonant Photocurrent at 1550 nm in an Erbium Low-Doped Silicon Transistor at Room Temperature (2019)
  • Author(s): E.Prati,M.Celebrano, L.Ghirardini, M.Finazzi,G.Ferrari, T.Shinada, K.Gi, Y.Chiba, A.Abdelghafar, M.Yano, T.Tanii
  • Organizer: 2019 Silicon Nanoelectronics Workshop
  • Int'l Joint Research
• [Presentation] 単一NVセンター規則配列と単一細胞パターニングを用いた神経細胞回路の自発発火パターンの長期計測に向けて (2019)
  • Author(s): 石田実穂子、石井邑、谷井孝至
  • Organizer: 量子生命科学会第1回大会
• [Presentation] ダイヤモンド中単一NVセンターのパルス光磁気共鳴測 定のためのローエンドFPGAへのフォトンカウンタの実装 (2019)
  • Author(s): 永岡 希朗, 畑 雄貴, 川勝 一斗, 石井 邑, 福田 諒 介, 寺地 徳之, 小野田 忍, 大島 武, 品田 高宏 , 川 原田 洋, 磯谷 順一, 谷井 孝至
  • Organizer: 第66回応用物理学会春季学術講演会
• [Presentation] C5N4Hnイオン注入による双極子結合したNVセンターの 形成 (2019)
  • Author(s): 春山 盛善, 小野田 忍, 樋口 泰成, 加田 渉, 千葉 敦也, 平野 貴美, 寺地 徳之, 五十嵐 龍治, 河合 空, 川原田 洋, 石井 邑, 福田 諒 介, 谷井 孝至, 磯谷 順一, 大島 武, 花泉 修
  • Organizer: 第66回応用物理学会春季学術講演会
• [Presentation] 高被覆率窒素終端(111)ダイヤモンドの作製 (2019)
  • Author(s): 立石 哲也, 薗田 隆弘, 河合 空, 山野 颯, Jorge J. Buendia, 蔭浦 泰資, 石井 邑 , 永岡 希朗, 福田 諒介, 谷井 孝至, 春山 盛善, 山田 圭介, 小 野田 忍, 加田 渉, 花泉 修, Alastair Stacey, 神田 一浩, 上村 雅治, 寺地 徳之, 磯谷 順一, 河野 省 三, 川原田
  • Organizer: 第66回応用物理学会春季学術講演会
• [Presentation] イオン注入による単一不純物欠陥の規則的配列形成をその応用 (2019)
  • Author(s): 谷井孝至、品田高宏、寺地徳之、小野田忍、大島武、McGuuinness Liam, Jelezko Fedor, Liu Yan, Wu E, 加田渉、花泉修、川原田洋、磯 谷順一
  • Organizer: 第66回応用物理学会春季学術講演会
  • Invited
• [Presentation] Implantation of nitrogen compound ion beam for fabricating coupled triple NV centers (2019)
  • Author(s): Shinobu Onoda, Moriyoshi Haruyama, Taisei Higuchi, Wataru Kada, Atsuya Chiba, Yoshimi Hirano,Tokuyuki Teraji, Ryuji Igarashi, Sora Kawai, Hiroshi Kawarada, Yu Ishii, Ryosuke Fukuda, Takashi Tanii, Junichi Isoya, Takeshi Ohshima, Osamu Hanaizumi
  • Organizer: Hasselt Diamond Workshop 2019
  • Int'l Joint Research
• [Presentation] Fabrication of color centers for quantum applications from singles to ensemble in HPHT single crystal diamond (2019)
  • Author(s): J. Isoya
  • Organizer: Hasselt Diamond Workshop 2
  • Int'l Joint Research / Invited
• [Presentation] C5N4Hnイオン注入による双極子結合したNVセンターの 形成 (2019)
  • Author(s): 春山 盛善, 小野田 忍, 樋口 泰成, 加田 渉, 千葉 敦也, 平野 貴美, 寺地 徳之, 五十嵐 龍治, 河合 空, 川原田 洋, 石井 邑, 福田 諒介, 谷井 孝至, 磯谷 順一, 大島 武, 花泉 修
  • Organizer: 第66回応用物理学会春季学術講演会
• [Presentation] 高被覆率窒素終端(111)ダイヤモンドの作製 (2019)
  • Author(s): 立石 哲也, 薗田 隆弘, 河合 空, 山野 颯, Jorge J. Buendia, 蔭浦 泰資, 石井 邑 , 永岡 希朗, 福田 諒介, 谷井 孝至, 春山 盛善, 山田 圭介, 小 野田 忍, 加田 渉, 花泉 修, Alastair Stacey, 神田 一浩, 上村 雅治, 寺地 徳之, 磯谷 順一, 河野 省 三, 川原田 洋
  • Organizer: 第66回応用物理学会春季学術講演会
• [Presentation] イオン注入による単一不純物欠陥の規則的配列形成をその応用 (2019)
  • Author(s): 谷井孝至、品田高宏、寺地徳之、小野田忍、大島武、McGuuinness Liam, Jelezko Fedor, Liu Yan, Wu E, 加田渉、花泉修、川原田洋、磯谷順一
  • Organizer: 第66回応用物理学会春季学術講演会
  • Invited
• [Presentation] Fabrication of color centers for quantum applications from singles to ensemble in HPHT single crystal diamond (2019)
  • Author(s): J. Isoya
  • Organizer: Hasselt Diamond Workshop 2019
  • Int'l Joint Research / Invited
• [Presentation] Fabrication of spin defects in diamond for quantum science and technology: from single to ensemble (2018)
  • Author(s): Shinobu Onoda, Tokuyuki Teraji, Hitoshi Sumiyama, Takashi Tanii, Junichi Isoya
  • Organizer: International Conference on challenges in Quantum Information Science CQIS2018
  • Int'l Joint Research
• [Presentation] Growth of single crystal diamond and fabrication of spin defects for quantum science and thchnology applications (2018)
  • Author(s): Junichi Isoya, Tokuyuki Teraji, Hitoshi Sumiyama, Shinobu Onoda, Takashi Tanii and Hiroshi Kawarada
  • Organizer: The 69th Diamond Conference
  • Int'l Joint Research / Invited
• [Presentation] Properties of Shallow Nitorogen Vacancy Centers in Nitrogen Terminated Diamond and Detection of Nuclear Magnetic Resonance (2018)
  • Author(s): Takahiro Sonoda, Sora Kawai, Hayate Yamano, Kanami, Kato, Jorge J, Buendia, Taisuke Kageura, Yu Ishii, Kiro Nagaoka, Ryosuke Fukuda, Takuma Okada, Moriyoshi Haruyama, Takashi, Tanii, Keisuke Yamada, Shinobu Onoda, Wataru Kada, Osamu Hanaizumi, Alastair Stacy, Tokuyuki Teraji, Shozo Kono, Junichi Isoya, Hiroshi Kawarada
  • Organizer: Solid State devices and Materials (SSDM) 2018
  • Int'l Joint Research
• [Presentation] シリコン中におけるエルビウム－酸素複合体の室温発光特性の理解 (2018)
  • Author(s): 清水 康雄、アブデルガファ 愛満、鈴木 雄大、魏 啓楠、谷井 孝至、品田 高宏、Prati Enrico、Celebrano Michele、Finazzi Marco、Ghirardini Lavinia、井上 耕治、永井 康介
  • Organizer: 第79回応用物理学会秋季学術講演会
• [Presentation] Controlled Creation of Erbium-Oxygen Centers in Silicon by Deterministic Ion Implantation for Room-Temperature Photoluminescence at Telecom Wavelength (2018)
  • Author(s): T. Tanii, Y. Suzuki, K. Gi, M. Celebrano, L. Ghirardini, P. Biagioni, M. Finazzi, Y. Shimizu, Y. Tu, K. Inoue, Y. Nagai, E. Prati, and T. Shinada
  • Organizer: 22nd International Conference on Ion Implantation Technology
  • Int'l Joint Research
• [Presentation] 浅い単一NVセンターの規則配列を用いたナノNMRのスピンノイズ解析 (2018)
  • Author(s): 石井邑、福田諒介、P. Balasubramanian、東又格、永岡希朗、河合空、薗田隆弘、寺地徳之、小野田忍、春山盛善、山田圭介、稲葉優文、山野颯、F. Stuerner、S. Schmitt、L. P. McGuinness、F. Jelezko、大島武、品田高宏、川原田洋、加田渉、花泉修、磯谷順一、谷井孝至
  • Organizer: 第79回応用物理学会秋季学術講演会
• [Presentation] 窒素終端ダイヤモンド中の浅い単一NVセンターを用いたNMR測定(Ⅱ) (2018)
  • Author(s): 立石哲也、薗田隆弘、河合空、山野颯、J. J. Buendia、蔭浦泰資、石井邑、永岡希朗、福田諒介、谷井孝至、春山盛善、山田圭介、小野田忍、加田渉、花泉修、A. Stacey、神田一浩、上村雅治、寺地徳之、磯谷順一、河野省三、川原田洋
  • Organizer: 第79回応用物理学会秋季学術講演会
• [Presentation] Lithographically Engineered Shallow Nitrogen-Vacancy Centers in Diamond for External Nuclear Spin Sensing (2018)
  • Author(s): 立石哲也、薗田隆弘、河合空、山野颯、J. J. Buendia、蔭浦泰資、石井邑、永岡希朗、福田諒介、谷井孝至、春山盛善、山田圭介、小野田忍、加田渉、花泉修、A. Stacey、神田一浩、上村雅治、寺地徳之、磯谷順一、河野省三、川原田洋
  • Organizer: 14th International Conference on Atomically Controlled Surfaces, Interfaces and Nanostructures (ACSIN-14)
  • Int'l Joint Research
• [Presentation] Computational Modeling of Spontaneous Firing Patterns Generated by Single Autaptic Neurons (2018)
  • Author(s): Kouhei Hattori, Takeshi Hayakawa, Akira Nakanishi, Mihoko Ishida, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: The 28th Annual Conference of the Japanese Neural Network Society
  • Int'l Joint Research
• [Presentation] 有機化合物イオン注入によるNVセンターの多量子ビット形成 (2018)
  • Author(s): 小野田忍、春山盛善、樋口泰成、加田渉、千葉敦也、平野貴美、寺地徳之、五十嵐龍治、河合空、川原田洋、石井邑、福田諒介、谷井孝至、磯谷順一、花泉修、大島武
  • Organizer: 第32回ダイヤモンドシンポジウム
• [Presentation] 窒素終端ダイヤモンド中の浅いNVセンターを用いた1H-NMR (2018)
  • Author(s): 立石哲也、薗田隆弘、河合空、山野颯、Jorge J. Buendia, 蔭浦泰資、石井邑、永岡希朗、福田諒介、谷井孝至、春山盛善、山田圭介、小野田忍、加田渉、花泉修、Alastair Stacey, 神田一浩、上村雅治、寺地徳之、磯谷順一、河野省三、川原田洋
  • Organizer: 第32回ダイヤモンドシンポジウム
• [Presentation] 1H NMR Detection on Nitrogen Terminated Diamond by Shallow Nitrogen Vacancy Centers (2018)
  • Author(s): Takahiro Sonoda, Sora Kawai, Hayate Yamano, Jorge J. Buendia, Taisuke Kageura, Yu Ishii, Kiro Nagaoka, Ryosuke Fukuda, Moriyoshi Haruyama, Takashi Tanii, Keisuke Yamada, Shinobu Onoda, Wataru Kada,Osamu Hanaizumi, Alastair Stacey, Kazuhiro Kanda, Takuyuki Teraji, Shozo Kono, Junichi Isoya, Hiroshi Kawarada
  • Organizer: 2018 MRS Fall Meeting
  • Int'l Joint Research
• [Presentation] Fabrication of coupled Nv centers by adenine ion beam implantation (2018)
  • Author(s): Shinobu Onoda, Moriyoshi Haruyama, Taisei Higuchi, Wataru Kada, Atsuya Chiba, Yoshimi Hirano,Tokuyuki Teraji, Ryuji Igarashi, Sora Kawai, Hiroshi Kawarada, Yu Ishii, Ryosuke Fukuda, Takashi Tanii, Junichi Isoya, Takeshi Ohshima, Osamu Hanaizumi
  • Organizer: The 1st International forum on Quantum sensing
  • Int'l Joint Research
• [Presentation] Surface modification with visible-light-responsible TiO2 thin film (2018)
  • Author(s): Atsushi Kurotobi, Sho Kono, Takayuki Ichikawa, Hideaki Yamamoto, Ayumi Hirano-Iwata and Tanii Takashi
  • Organizer: The 7th RIEC International Symposium on Brain Functions and Brain Computer
  • Int'l Joint Research
• [Presentation] An experimental study on spontaneous firing of a single neuron on micropatterned substrates (2018)
  • Author(s): Koki Sato, Takahiro Nakane, Honoka Takahashi, Kouhei Hattori, Hideaki Yamamoto, Ayumi Hirano-Iwata and Takashi Tanii
  • Organizer: The 7th RIEC International Symposium on Brain Functions and Brain Computer
  • Int'l Joint Research
• [Presentation] Computational modeling of spontaneous firing patterns generated by single autaptic neurons (2018)
  • Author(s): Kouhei Hattori, Takeshi Hayakawa, Akira Nakanishi, Mihoko Ishida, Hideaki Yamamoto, Ayumi Hirano-Iwata, Takashi Tanii
  • Organizer: The 7th RIEC International Symposium on Brain Functions and Brain Computer
  • Int'l Joint Research
• [Presentation] Revisiting room-temperature 1.54 um photoluminescence of ErOx centers in silicon at extremely low concentration (2017)
  • Author(s): Enrico Prati, Michele Celebrano, Lavinia Ghirardini, Paolo Biagioni, Marco Finazzi, Yasuo Shimizu, Yuan Tu, Koji Inoue, Yasuyoshi Nagai, Takahiro Shinada, Yuki Chiba, Ayman Abdelghafar, Maasa Yano, Takashi Tanii
  • Organizer: 2017 Silicon Nanoelectronics Workshop
  • Int'l Joint Research
• [Presentation] Atom Probe Study of Erbium and Oxygen Co‐Implanted Silicon (2017)
  • Author(s): Yasuo Shimizu, Yuan Tu, Ayman Abdelghafar, Maasa Yano, Yudai Suzuki, Takashi Tanii, Takahiro Shinada, Enrico Prati, Michele Celebrano, Marco Finazzi, Lavinia Ghirardini, Koji Inoue, and Yasuyoshi Nagai
  • Organizer: 2017 Silicon Nanoelectronics Workshop
  • Int'l Joint Research
• [Presentation] マイクロ構造に対する接着差を利用した癌・正常細胞選別ー表面接着性によるライブセル・ラベルフリーな癌・正常細胞判別胞の提案ー (2017)
  • Author(s): 若林洸、竹内祐子、田中学、谷井孝至
  • Organizer: 第37回 表面科学学術講演会
• [Presentation] 可視光応答酸化チタンの光触媒作用を活用した液中表面改質と細胞パターニング (2017)
  • Author(s): 河野翔、黒飛敦 、服部晃平、山本英明、平野愛弓、谷井孝至
  • Organizer: 第37回 表面科学学術講演会
• [Presentation] 窒素終端およびシリコン終端ダイヤモンド中の浅いNVセンターのスピン特性 (2017)
  • Author(s): 薗田隆弘, 河合空, 山野颯, 加藤かなみ, 蔭浦泰資, 福田諒介,岡田拓真, 春山盛善, 谷井孝至, 山田啓介, 小野田忍,寺地徳之, 加田渉, 花泉修, 河野省三, 磯谷順一, 川原田洋
  • Organizer: 第78回応用物理学会秋季学術講演会
• [Presentation] シリコン中に共注入した酸素がエルビウム分布に与える影響 (2017)
  • Author(s): 清水 康雄，Yuan Tu，アブデルガファ 愛満，矢野 真麻，鈴木 雄大，谷井 孝至，品田 高宏, Enrico Prati，Michele Celebrano，Marco Finazzi，Lavinia Ghirardini，井上 耕治，永井 康介
  • Organizer: 第78回応用物理学会秋季学術講演会
• [Presentation] 可視光応答酸化チタン薄膜の光触媒能を利用した細胞の液中パターニング（II） (2017)
  • Author(s): 河野翔、黒飛敦 、服部晃平、山本英明、谷井孝至
  • Organizer: 第78回応用物理学会秋季学術講演会
• [Presentation] 生体分子パターンの形状による神経細胞回路のモジュー ル間相互作用の制御 (2017)
  • Author(s): 井手克哉、山本英明、守谷哲、脇村桂、谷井孝至、秋間学尚、久保田繁、佐藤茂雄、 庭野道夫、平野愛弓
  • Organizer: 第78回応用物理学会秋季学術講演会
• [Presentation] Charge Stability of Shallow Nitrogen Vacancy Center in Diamond with Radical Exposure Nitridation Surface for DNA Detection (2017)
  • Author(s): Sora Kawai, Hayate Yamano, Miki Kajiya, Kanami Kato, Jorge J. Buendia, Taisuke Kageura, Masafumi Inaba, Ryosuke Fukuda, Takuma Okada,Itaru Higashimata, Moriyoshi Haruyama, Takashi Tanii, Shinobu Onoda, Wataru Kada, Osamu Hanaizumi, Tokuyuki Teraji, Shozo Kono, Junichi Isoya and Hiroshi Kawarada
  • Organizer: 2017 International Conference on Solid State Devices and Materials
  • Int'l Joint Research
• [Presentation] An experimental and computational study on spontaneous firing pattern of a single neuron (2017)
  • Author(s): Kouhei Hattori, Sho Kono, Tomoya Yoneyama, Akira Nakanishi, Hideaki Yamamoto and Takashi Tanii
  • Organizer: 第27回日本神経回路学会全国大会
• [Presentation] 窒素終端ダイヤモンド中の浅いNVセンターのスピン特性 (2017)
  • Author(s): 薗田隆弘、河合空、山野颯、加藤かなみ、J. J. Buendia、蔭浦泰資、福田諒介、岡田拓真、谷井孝至、春山盛喜、山田圭介、小野田忍、加田渉、花泉修、寺地徳之、磯谷順一、A. Stacey、河野省三、川原田洋
  • Organizer: 第31回ダイヤモンドシンポジウム
• [Presentation] Charge Stability and Coherence Property of Shallow Nitrogen Vacancy Center in Nitrogen Terminated Diamond for DNA Detection (2017)
  • Author(s): S. Kawai, H. Yamano, T. Sonoda, K. Kato, J. J. Buendia, E. Suaebah,T. Kageura, M. Inaba, R. Fukuda, T. Okada, M. Haruyama, T. Tanii, K. Yamada, S. Onoda, W. Kada, O. Hanaizumi, A. Stacey, T. Teraji, S.Kono, J. Isoya, H. Kawarada
  • Organizer: 2017 MRS Fall & Exhibit
  • Int'l Joint Research