| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2019: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2017: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Outline of Final Research Achievements |
In this study, we designed and synthesized a D-π-D type caged benzoic acid based on a π-expanded coumarin chromophore with a relatively high two-photon absorption cross section (σ2 = 855 GM). Its photoreactivity was investigated. As a result, benzoic acid was obtained in a yield of about 50%, and 4 types of coumarin-derived products were successfully isolated. In addition, we designed a caged benzoic acid with an indene skeleton that can be expected to undergo skeletal changes before and after light irradiation. Its photochemical properties and the generation of benzoic acid by the photodissociation reaction were investigated. As a result, the process of quantitatively releasing benzoic acid with time was confirmed by 1H NMR, and efficient uncaging was achieved.
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