Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2019: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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Outline of Final Research Achievements |
We have developed catalyzed enantioselective reactions by means of chiral phosphoric acid, such as 1) Friedel-Crafts alkylation reactions of pyrrole with N-H CF3 ketimines, 2) Friedel-Crafts alkylation reaction of indole with nitroalkene, 3) dehydrohydrogenation of 2-indolylalcohols, 4) reduction of nitroarenes by use of benzothiazoline and its application to enantioselective synthesis of 2-aryltetrahydroquinoline, 5) [3+2] cycloaddition reaction, and 5) internal redox reaction.
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