| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2019: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2017: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Outline of Final Research Achievements |
Focusing on the processes of vascular network formation in mouth retina, we develop a scheme for obtaining the structures of vascular network before and after pruning from a confocal image of a single sample. This allows us to analyze the impact of pruning on blood flow distribution by using computational fluid dynamics. Through the analysis, we found clear and distinct trends of pruning close to the inlet of the artery and the angiogenic front. Based on such findings, we develop a new strategy for optimizing fluid network structure.
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