• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A graphene resonator by low-pressure dry transfer technique for highly sensitive chemical sensor

Research Project

Project/Area Number 17H03251
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Electron device/Electronic equipment
Research InstitutionToyohashi University of Technology

Principal Investigator

TAKAHASHI Kazuhiro  豊橋技術科学大学, 工学(系)研究科(研究院), 准教授 (90549346)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2019: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2018: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2017: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Keywordsグラフェン / 転写技術 / MEMS共振器 / 化学センサ / MEMS
Outline of Final Research Achievements

In this study, we have developed a suspended graphene-based MEMS (Micro Electro Mechanical Systems) sensor for ultra-sensitive detection of biomolecules and chemical substances. We developed a low pressure dry transfer technique of CVD (Chemical Vapor Deposition) graphene onto a silicon substrate with cavities, enabling receptor modification on the suspended graphene with the sealed cavity by wet treatment. As a result, we demonstrated selective molecular detection for the first time on the suspended graphene, achieving a concentration detection limit of 150 zM and mass detection limit of 2.01 zg/Hz.

Academic Significance and Societal Importance of the Research Achievements

提案するMEMS型のセンサは、従来の標識法を用いた分子検出技術とは異なり、分子サイズの大きいバイオマーカーを複数種類並列処理を行うことができ、濃度検出下限も従来技術を1桁上回る特性が得られた。また、吸着分子量を定量するための質量測定を行い、質量検出下限は従来比200倍を達成した。さらに、小型で携帯可能なセンサシステムを目指し、半導体チップ上での検出に向けて、CMOS検出回路との一体化の見通しが得られた。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (19 results)

All 2020 2019 2018 2017 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (14 results) (of which Int'l Joint Research: 4 results) Remarks (3 results)

  • [Journal Article] Suspended graphene-based optical interferometric surface stress sensor for selective biomolecular detection2020

    • Author(s)
      S. Kidane, H. Ishida, K. Sawada, K. Takahashi
    • Journal Title

      Nanoscale Advances

      Volume: 2 Issue: 4 Pages: 1431-1436

    • DOI

      10.1039/c9na00788a

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Vacuum-sealed microcavity formed from suspended graphene by using a low-pressure dry transfer technique2018

    • Author(s)
      K. Takahashi, H. Ishida, and K. Sawada
    • Journal Title

      Applied Physics Letters

      Volume: 112 Issue: 4 Pages: 041901-041901

    • DOI

      10.1063/1.5008595

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 分子選択性を持つグラフェン共振センサによる高感度質量計測2020

    • Author(s)
      喜種慎、澤田和明、高橋一浩
    • Organizer
      第67回応用物理学会春季学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ひずみ印加によるキャビティ封止型グラフェン共振器の共振特性向上2020

    • Author(s)
      上坂淳平、喜種慎、澤田和明、高橋一浩
    • Organizer
      第67回応用物理学会春季学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 架橋グラフェンを用いた光干渉型表面応力バイオセンサの検出感度解析と抗原抗体反応検出2019

    • Author(s)
      喜種 慎,澤田 和明,高橋 一浩
    • Organizer
      電子情報通信学会 電子デバイス研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Fabrication of tensile strain applying structure to suspended graphene for nanomechanical resonator with high fQ product2019

    • Author(s)
      J. Uesaka, K. Go, S. Kidane, K. Sawada, K. Takahashi
    • Organizer
      2019 International Conference on Solid State Devices and Materials (SSDM2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 超高感度非標識生体分子計測に向けたグラフェン光干渉型表面応力センサ2019

    • Author(s)
      喜種 慎, 澤田 和明, 高橋 一浩
    • Organizer
      第36回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] 高FQ積を備えたナノメカニカル共振器に向けた架橋グラフェンへの引っ張り歪印加構造の作製2019

    • Author(s)
      上坂 淳平, 郷 幸佑, 喜種 慎, 澤田 和明, 高橋 一浩
    • Organizer
      第36回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] 光励振法を用いたグラフェン共振器の固有振動数評価2019

    • Author(s)
      髙橋一浩、石田隼人、喜種慎、岩田達也、澤田和明
    • Organizer
      第11回 集積化MEMSシンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] 減圧ドライ転写法によるサスペンデットグラフェンを用いたMEMSバイオセンサ2018

    • Author(s)
      喜種慎,石田隼斗, 澤田和明, 髙橋一浩
    • Organizer
      電子情報通信学会電子デバイス研究会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Evaluation of antigen-antibody reaction on suspended graphene by optical interferometry2018

    • Author(s)
      S. Kidane, H. Ishida, K. Sawada, and K. Takahashi
    • Organizer
      Asia-Pacific Conference of Transducers and Micro-Nano Technology 2018
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optical interferometry-based surface stress sensor using suspended graphene2018

    • Author(s)
      S. Kidane, H. Ishida, K. Sawada, and K. Takahashi
    • Organizer
      2018 Int. Conf. on Optical MEMS an Nanophotonics 2018 (OMN 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 自立グラフェンを利用した光干渉型表面応力バイオセンサ2018

    • Author(s)
      喜種慎, 石田隼人, 澤田和明, 高橋一浩
    • Organizer
      第35回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] 減圧ドライ転写法により作製したサスペンデッドグラフェン上での選択的分子検出2018

    • Author(s)
      喜種 慎、石田隼斗、澤田和明、高橋一浩
    • Organizer
      第65回応用物理学会春季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 減圧ドライ転写技術を用いた真空キャビティ構造をもつグラフェン共振器の製作2017

    • Author(s)
      石田 隼斗, 岩田 達哉, 澤田 和明, 髙橋 一浩
    • Organizer
      第34回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Selective molecular detection on a suspended graphene developed by low-pressure dry transfer technique2017

    • Author(s)
      S. Kidane, H. Ishida, K. Sawada, and K. Takahashi
    • Organizer
      The 30th International Microprocesses and Nanotechnology Conference (MNC 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Remarks] 豊橋技術科学大学 電気・電子情報工学系 集積化バイオセンサ・MEMSグループホームページ

    • URL

      http://int.ee.tut.ac.jp/bio/

    • Related Report
      2019 Annual Research Report
  • [Remarks] 集積化バイオセンサ・MEMSグループホームページ

    • URL

      http://int.ee.tut.ac.jp/bio/

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://int.ee.tut.ac.jp/bio/

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi