| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2019: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2017: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Outline of Final Research Achievements |
Nerves have long projections called axons, and when they are physically severed, various neurological disorders occur. Many nerves have the ability to regenerate severed axons, but the molecular mechanisms that induce regeneration are only partially understood. In this study, we attempted to identify and analyze the novel factors that regulate axon regeneration using the model organism C. elegans. As a result, we identified many regulatory factors, including several svh genes, and clarified their functions and roles in axon regeneration.
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