| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2019: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2018: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
The aim of this research project was to explore developmental mechanisms underlying species-specific anatomical structures in amniote pallium (the dorsal part of the telencephalon), by using quantitative and qualitative analyses of cellular dynamics in early brain development. During the course of the project,I have succeeded to obtain following findings: 1) changes in cis-regulatory regions underlying neuron subtype-specific transcriptional regulations in the developing amniote pallium, 2) the role of sonic hedgehog signaling in the formation of anatomical diversity of the pallium, and 3) changes in Wnt-dependent neuronal morphology underlie anatomical diversities in the developing amniote pallium.
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