| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
Multicellular organisms often exert tumor suppressive mechanism that eliminates abnormal cells from the tissue. In this study, we found in the Drosophila epithelium that Slit-Robo2 repulsive signaling contributes to epithelial wound repair by promoting extrusion of dying cells from the wounded tissue caused by physical injury, which facilitates transient and appropriate induction of growth factors for proper wound healing.
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