| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Outline of Final Research Achievements |
During development and organogenesis, cells form populations with defined size and shape and form the boundaries between different cell populations. In this process, cell-cell interactions between cells of the same and different types play an important role. In this study, I focused on the body surface pattern of zebrafish and clarified the formation mechanism of the boundary between black and yellow pigment cells, each of which forms a population and has a certain size, and the boundary between black and yellow pigment cells (repeated structure and pattern). We focused on connexins, gap junction proteins, as important molecules involved in cell-cell interactions and analyzed their functions in pigment cells.
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