| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2020: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2019: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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| Outline of Final Research Achievements |
We have tried to identify novel factors interacting with GCS1, the male-side gamete fusion factor conserved among animals, plants and protists, using the rodent malaria parasite Plasmodium berghei. We succeeded in producing parasites expressing GCS1 conjugated with BioID2, which was recently developed as a proximity-dependent biotin ligase. Although we have not been able to detect female-side partners of GCS1, our findings suggest a promising possibility to identify fertilization factors.
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