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Effects of exercise and heat adaptation on thermal sensation and tolerance in the elderly

Research Project

Project/Area Number 17H03741
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied anthropology
Research InstitutionOsaka City University

Principal Investigator

Okazaki Kazunobu  大阪市立大学, 都市健康・スポーツ研究センター, 教授 (70447754)

Co-Investigator(Kenkyū-buntansha) 横山 久代  大阪市立大学, 都市健康・スポーツ研究センター, 准教授 (10647829)
今井 大喜  大阪市立大学, 都市健康・スポーツ研究センター, 講師 (40614483)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2019: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2018: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2017: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Keywords体温調節能 / 加齢 / 暑熱環境 / 運動トレーニング
Outline of Final Research Achievements

We performed three studies to test the hypothesis that age-related decrease in aerobic capacity causes the blunted thermal sensation observed in the seniors. In study 1, we observed that whole body thermal sensation was comparable while skin warm sensation threshold was lower in elderly group compared with young group even their aerobic capacity was same. In study 2, we observed that whole body thermal sensation and skin warm and cold sensation threshold were higher in the higher aerobic capacity group compared with the lower aerobic capacity group in the elderly. In study 3, we observed that whole body thermal sensation and skin warm and cold sensation threshold were improved after endurance exercise training in the elderly.

Academic Significance and Societal Importance of the Research Achievements

近年、皮膚および深部の温度感覚受容の詳細な経路が解明され、TRPVチャネルなどの温度センサーの詳細が明らかになってきている。しかし、ヒトにおいて温度感覚と生体諸機能との関連について検討した研究は極めて少ない。本研究は、高齢者の暑熱環境下における温度感覚の劣化の一部は、全身持久力の低下によって引き起こされることを示した点で学術的意義が高い。また、本研究の成果は、高齢者の熱中症予防のための、科学的根拠に基づいた安全で効果的な方法の開発の重要な基礎データとなる点で社会的意義が高い。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (44 results)

All 2019 2018 2017

All Journal Article (12 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 8 results,  Open Access: 3 results) Presentation (32 results) (of which Int'l Joint Research: 18 results,  Invited: 8 results)

  • [Journal Article] Iron insufficiency diminishes the erythropoietic response to moderate altitude exposure2019

    • Author(s)
      Okazaki Kazunobu、Stray-Gundersen James、Chapman Robert F.、Levine Benjamin D.
    • Journal Title

      Journal of Applied Physiology

      Volume: 127 Issue: 6 Pages: 1569-1578

    • DOI

      10.1152/japplphysiol.00115.2018

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The effects of aging on the distribution of cerebral blood flow with postural changes and mild hyperthermia2019

    • Author(s)
      Ota Akemi、Takeda Ryosuke、Imai Daiki、Naghavi Nooshin、Kawai Eriko、Saho Kosuke、Morita Emiko、Suzuki Yuta、Yokoyama Hisayo、Miyagawa Toshiaki、Okazaki Kazunobu
    • Journal Title

      European Journal of Applied Physiology

      Volume: 119 Issue: 5 Pages: 1261-1272

    • DOI

      10.1007/s00421-019-04118-5

    • NAID

      120006849936

    • URL

      https://ocu-omu.repo.nii.ac.jp/records/2019882

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aerobic Exercise Training with Brisk Walking Increases Intestinal Bacteroides in Healthy Elderly Women2019

    • Author(s)
      Morita、Yokoyama、Imai、Takeda、Ota、Kawai、Hisada、Emoto、Suzuki、Okazaki
    • Journal Title

      Nutrients

      Volume: 11 Issue: 4 Pages: 868-868

    • DOI

      10.3390/nu11040868

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Body Temperature Regulation During Exercise and Hyperthermia in Diabetics2018

    • Author(s)
      Takeda R, Okazaki K
    • Journal Title

      InTechOpen - Diabetes

      Volume: - Pages: 89-108

    • DOI

      10.5772/intechopen.74063

    • ISBN
      9781789230345, 9781789230352
    • URL

      https://ocu-omu.repo.nii.ac.jp/records/2020772

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of skin surface cooling before exercise on lactate accumulation in cool environment2018

    • Author(s)
      Imai D, Takeda R, Suzuki A, Naghavi N, Yamashina Y, Matsumura S, Yokoyama H, Miyagawa T, Okazaki K
    • Journal Title

      European Journal of applied Physiology

      Volume: 118 Issue: 3 Pages: 551-562

    • DOI

      10.1007/s00421-017-3797-4

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibitory Effects of Intranasal Administration of Insulin on Fat Oxidation during Exercise Are Diminished in Young Overweight Individuals2018

    • Author(s)
      Yokoyama Hisayo、Takeda Ryosuke、Kawai Eriko、Ota Akemi、Morita Emiko、Imai Daiki、Suzuki Yuta、Morioka Tomoaki、Emoto Masanori、Inaba Masaaki、Okazaki Kazunobu
    • Journal Title

      Journal of Clinical Medicine

      Volume: 7 Issue: 10 Pages: 308-308

    • DOI

      10.3390/jcm7100308

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of 2-Year Cognitive?Motor Dual-Task Training on Cognitive Function and Motor Ability in Healthy Elderly People: A Pilot Study2018

    • Author(s)
      Morita Emiko、Yokoyama Hisayo、Imai Daiki、Takeda Ryosuke、Ota Akemi、Kawai Eriko、Suzuki Yuta、Okazaki Kazunobu
    • Journal Title

      Brain Sciences

      Volume: 8 Issue: 5 Pages: 86-86

    • DOI

      10.3390/brainsci8050086

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid saline infusion and/or drinking enhance skin sympathetic nerve activity components reduced by hypovolaemia and hyperosmolality in hyperthermia2018

    • Author(s)
      Kamijo Yoshi-ichiro、Okazaki Kazunobu、Ikegawa Shigeki、Okada Yoshiyuki、Nose Hiroshi
    • Journal Title

      The Journal of Physiology

      Volume: 596 Issue: 22 Pages: 5443-5459

    • DOI

      10.1113/jp276633

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 運動時の体液変化とその循環および体温調節への影響2018

    • Author(s)
      岡崎和伸
    • Journal Title

      循環制御

      Volume: 39 Pages: 82-90

    • Related Report
      2018 Annual Research Report
  • [Journal Article] 暑さ対策としての水分補給2018

    • Author(s)
      岡崎和伸
    • Journal Title

      臨床スポーツ医学

      Volume: 35 Pages: 676-683

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Effect of stimulation of odor of essential oil on muscle sympathetic nervous activity2017

    • Author(s)
      Kawai E, Hanno G, Takeda R, Ota A, Morita E, Imai D, Suzuki Y, Yokoyama H, Okazaki K
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 6 Pages: 447-447

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Effects of a 3-month walking training on thermal sensation in healthy elderly men2017

    • Author(s)
      Takeda R, Imai D, Ota A, Kawai E, Hanno G, Naghavi N, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 6 Pages: 497-497

    • Related Report
      2017 Annual Research Report
  • [Presentation] Expanded plasma volume after a bout of exercise increases erythropoietin secretion to hypoxia2019

    • Author(s)
      Okazaki K, Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Goto K, Yokoyama H
    • Organizer
      9th FAOPS congress 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of aging on event-related potentials during mild-hyperthermia2019

    • Author(s)
      Ota A, Takeda R, Imai D, Kawai E, Saho K, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      9th FAOPS congress 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Exercise habit is associated with lower fall risks among elderly people living in urban areas2019

    • Author(s)
      Yokoyama H, Watanabe H, Saito K, Shibata A, Suzuki Y, Imai D, Okazaki K, Ogita A
    • Organizer
      1st World Congress on Falls and Postural Stability
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 寒冷および精神性ストレスによる複合ストレスが持久的運動パフォーマンスに及ぼす影響2019

    • Author(s)
      今井大喜,竹田良祐,河合英理子,佐保光祐,太田暁美,森田恵美子,鈴木雄太,横山久代,岡崎和伸
    • Organizer
      第 74 回日本体力医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 消防士における暑馴化プログラムが体温調節能および熱快適性に及ぼす影響2019

    • Author(s)
      佐保光祐,竹田良祐,今井大喜,河合英理子,太田暁美,森田恵美子,鈴木雄太,横山久代,木村祐,林宏和,岩渕幸弘,林英士,高橋秀也,岡崎和伸
    • Organizer
      第 74 回日本体力医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Research for the relationship between endurance athletic performance and blood volume2019

    • Author(s)
      Okazaki K, Shirai N, Enomoto Y
    • Organizer
      ARIHHP, Science Week 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 消防士に対する勤務時の暑熱順化プログラムが消防服着用による運動時の体温調節応答に及ぼす影響2019

    • Author(s)
      岡崎和伸, 林英士, 高橋秀也
    • Organizer
      第58回日本生気象学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Heat acclimation program for firefighters reduced heat stress and improved thermal sensation and thermal comfort during exercise wearing with a firefighting suit2019

    • Author(s)
      Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Yokoyama H, Takahashi H, Hayashi H, Kimura T, Okazaki K
    • Organizer
      Experimental Biology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of fragrance inhalation of Grapefruit essential oil on blood pressure and baroreflex sensitivity in human with and without family history of hypertension2019

    • Author(s)
      Kawai E, Takeda R, Saho K, Ota A, Morita E, Imai D, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      Experimental Biology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of mild hyperthermia on event related potential in the elderly2019

    • Author(s)
      Ota A, Takeda R, Imai D, Kawai E, Saho K, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      Experimental Biology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Erythropoietin secretion to hypoxia is enhanced with an expanded plasma volume after a bout of exercise in warm environment2019

    • Author(s)
      Okazaki K, Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Goto K, Yokoyama H
    • Organizer
      Experimental Biology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Improved thermal comfort were associated with the attenuated heat stress during exercise wearing with a firefighting suit after heat acclimation program for firefighters2019

    • Author(s)
      Okazaki K, Takeda R, Saho K, Imai D, Kawai E, Ota A, Morita E, Suzuki Y, Yokoyama H, Hayashi H, Takahashi H
    • Organizer
      14th International Congress of Physiological Anthropology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 消防士に対する勤務時の暑熱馴化プログラムが 体温調節能および温度感覚や熱快適性に及ぼす影響2019

    • Author(s)
      佐保光祐,竹田良祐,今井大喜,太田暁美,河合英理子,森田恵美子,鈴木雄太,横山久代,岡崎和伸
    • Organizer
      環境生理プレコングレス
    • Related Report
      2019 Annual Research Report
  • [Presentation] Effective strategies to enhance endurance athletic performance in summer games2019

    • Author(s)
      Okazaki K
    • Organizer
      ARIHHP, Human High Performance International forum 2019
    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Recent trend of altitude training for Japanese athletes2019

    • Author(s)
      Okazaki K
    • Organizer
      Belt & Road Altitude Training
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 運動生理学を基盤とした暑熱環境下の運動パフォーマンス向上2019

    • Author(s)
      岡崎和伸
    • Organizer
      第27回日本運動生理学会大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 中学・高校生期に求められる身体活動・運動量2019

    • Author(s)
      岡崎和伸
    • Organizer
      第74回日本体力医学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 暑熱馴化と熱中症対策2019

    • Author(s)
      岡崎和伸
    • Organizer
      第20回 和歌山救急・災害医療研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Improvement of thermoregulation under the heat for the seniors2018

    • Author(s)
      Okazaki K
    • Organizer
      nternational Symposium of Sports Medical Science for Person with Impairments in Wakayama 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Enhancement of endurance performance with heat and hypoxia2018

    • Author(s)
      Okazaki K
    • Organizer
      Satellite Symposium, Clinical Auditorium II
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Plasma volume expansion after exercise in a warm condition enhances erythropoietin release to hypoxia2018

    • Author(s)
      Okazaki K, Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Goto K, Yokoyama H
    • Organizer
      Physiology and Pharmacology of Temperature Regulation 7th International Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高強度間欠的運動時の心拍応答に及ぼす皮膚温度上昇の影響2018

    • Author(s)
      竹田良祐,今井大喜,河合英里子,太田暁美,佐保光祐,森田恵美子,鈴木雄太,横山久代,岡崎和伸
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Exercise in a warm condition enhances plasma volume expansion compared to a cool condition with an increased skin but not core temperature2018

    • Author(s)
      Okazaki K, Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Yokoyama H
    • Organizer
      Experimental Biology 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effects of core and skin temperatures and dehydration on heart rate response during interval exercise in warm and cool conditions2018

    • Author(s)
      Takeda R, Imai D, Kawai E, Ota A, Saho K, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      Experimental Biology 2018
    • Related Report
      2018 Annual Research Report
  • [Presentation] 運動による健康寿命の延伸について2018

    • Author(s)
      岡崎和伸
    • Organizer
      第56回近畿公衆衛生学会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Enhanced Thermoregulatory Adaptation with Nutritional Supplementation In Conjunction with Exercise Training2018

    • Author(s)
      Okazaki K
    • Organizer
      Food and Nutrition 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of odor stimulation with essential oil on muscle sympathetic nerves activity in humans2017

    • Author(s)
      Kawai E, Hanno G, Takeda R, Ota A, Morita E, Imai D, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      The 17th International Conference on Environmental Ergonomics ICEE 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Whole body and skin termal sensation are not improved with regular exercise in elderly men2017

    • Author(s)
      Takeda R, Imai D, Ota A, Kawai E, Hanno G, Naghavi N, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      The 17th International Conference on Environmental Ergonomics ICEE 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 定期的運動の実施が高齢者の温度感覚に及ぼす影響2017

    • Author(s)
      竹田良祐,今井大喜,太田暁美,河合英里子,半野源太,Naghavi Nooshin,森田恵美子,鈴木雄太,横山久代,岡﨑和伸
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 精油の臭い刺激が筋交感神経活動に及ぼす影響2017

    • Author(s)
      河合英里子,半野源太,竹田良祐,太田暁美,森田恵美子,今井大喜,鈴木雄太,横山久代,岡﨑和伸
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A 3-month walking training does not improve thermal sensation in healthy elderly men2017

    • Author(s)
      Takeda R, Imai D, Ota A, Kawai E, Hanno G, Naghavi N, Morita E, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Change in blood pressure by inhalation of fragrance of essential oil and muscle sympathetic nerve activity activity2017

    • Author(s)
      Kawai E, Hanno G, Takeda R, Ota A, Morita E, Imai D, Suzuki Y, Yokoyama H, Okazaki K
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report

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Published: 2017-04-28   Modified: 2021-02-19  

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