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Elucidation of the function of genes regulating development and morphogenesis in rice.

Research Project

Project/Area Number 17H03745
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Science in genetics and breeding
Research InstitutionThe University of Tokyo

Principal Investigator

Hirano Hiroyuki  東京大学, 大学院理学系研究科(理学部), 教授 (00192716)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2019: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2017: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords発生・分化 / メリステム / 葉の発生・形態形成 / 分げつ / 腋芽形成 / 遺伝子 / 翻訳制御 / イネ (Oryza sativa) / 発生分化 / 腋芽メリステム / 幹細胞 / 葉の発生 / Elongator complex / 葉の発生・分化 / イネ / 形態形成 / 葉 / 発生遺伝学 / イネ(Oryza sativa) / エピジェネティック制御 / ヒストン脱アセチル化酵素 / 葉の発生分化 / 転写制御 / エピジェネティックス / WOX遺伝子
Outline of Final Research Achievements

Understanding of the function of genes regulating plant development is essential for the improvement of crops based on morphological characters by molecular breeding. In this study, we aimed to elucidate the molecular mechanisms underlying development of rice (Oryza sativa), which is an important crop and is suitable for molecular genetics. Using morphological mutants, we identified several new genes responsible for leaf morphogenesis and axillary shoot (tiller) formation, and revealed their molecular functions and their roles in these developmental events. In addition, we found a key gene that regulate differentiation and activity of leaf cells at the early developmental stage, and elucidated a gene network involved in the maintenance of stem cells during axillary meristem formation.

Academic Significance and Societal Importance of the Research Achievements

本研究の成果は,イネの葉の形態形成や分げつ機構の理解を深めるのみでなく,その機能をシロイヌナズナなどの真正双子葉植物と比較することより,遺伝子機能の共通性や独自性の理解も進むことが期待される。したがって,本研究はイネという単独の植物の発生機構の理解にとどまらず,被子植物の発生や遺伝子機能の進化などの理解にも貢献すると考えられる。
また,分げつ形成は穂の数の制御に直結し,葉のサイズや形態は光合成機能とも関わってくる。したがって,イネの発生機構の理解は,作物としてのイネの形態改変にも重要な知見を与えることになり,品種改良による収量増産など農業にも貢献すると考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (38 results)

All 2020 2019 2018 2017 Other

All Journal Article (11 results) (of which Peer Reviewed: 10 results,  Open Access: 4 results) Presentation (25 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Stem Cell Maintenance in the Shoot Apical Meristems and during Axillary Meristem Development2020

    • Author(s)
      Hiro-Yuki Hirano, and Wakana Tanaka
    • Journal Title

      CYTOLOGIA

      Volume: 85 Issue: 1 Pages: 3-8

    • DOI

      10.1508/cytologia.85.3

    • NAID

      130007815401

    • ISSN
      0011-4545, 1348-7019
    • Year and Date
      2020-03-25
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DWARF WITH SLENDER LEAF1 encoding a histone deacetylase plays diverse roles in rice development2020

    • Author(s)
      Kubo Clara Fumika, Yasui Yukiko, Ohmori Yoshihiro, Kumamaru Toshihiro, Tanaka Wakana, Hirano Hiro-Yuki
    • Journal Title

      Plant and Cell Physiology

      Volume: 61 Pages: 457-469

    • DOI

      10.1093/pcp/pcz210

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antagonistic action of TILLERS ABSENT1 and FLORAL ORGAN NUMBER2 regulates stem cell maintenance during axillary meristem development in rice2020

    • Author(s)
      Wakana Tanaka, and Hiro-Yuki Hirano
    • Journal Title

      New Phytologist

      Volume: 225 Issue: 2 Pages: 974-984

    • DOI

      10.1111/nph.16163

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Class I KNOX Gene <i>OSH1</i> is Indispensable for Axillary Meristem Development in Rice2019

    • Author(s)
      Wakana Tanaka, Katsutoshi Tsuda, and Hiro-Yuki Hirano
    • Journal Title

      CYTOLOGIA

      Volume: 84 Issue: 4 Pages: 343-346

    • DOI

      10.1508/cytologia.84.343

    • NAID

      130007769479

    • ISSN
      0011-4545, 1348-7019
    • Year and Date
      2019-12-25
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Transcriptional Corepressor ASP1 and CLV-Like Signaling Regulate Meristem Maintenance in Rice2019

    • Author(s)
      Suzuki Chie、Tanaka Wakana、Hirano Hiro-Yuki
    • Journal Title

      Plant Physiology

      Volume: 180 Issue: 3 Pages: 1520-1534

    • DOI

      10.1104/pp.19.00432

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TILLERS ABSENT1, the WUSCHEL ortholog, is not involved in stem cell maintenance in the shoot apical meristem in rice2019

    • Author(s)
      Chie Suzuki, Wakana Tanaka, Hiroyuki Tsuji, and Hiro-Yuki Hirano
    • Journal Title

      Plant Signaling & Behavior

      Volume: 14 Issue: 9 Pages: 1640565-1640565

    • DOI

      10.1080/15592324.2019.1640565

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] BELL1-like homeobox genes regulate inflorescence architecture and meristem maintenance in rice2019

    • Author(s)
      Ikeda Takuyuki、Tanaka Wakana、Toriba Taiyo、Suzuki Chie、Maeno Akiteru、Tsuda Katsutoshi、Shiroishi Toshihiko、Kurata Tetsuya、Sakamoto Tomoaki、Murai Masayuki、Matsusaka Hiroaki、Kumamaru Toshihiro、Hirano Hiro-Yuki
    • Journal Title

      The Plant Journal

      Volume: 印刷中 Issue: 3 Pages: 465-478

    • DOI

      10.1111/tpj.14230

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rice flower development revisited: regulation of carpel specification and flower meristem determinacy.2019

    • Author(s)
      Sugiyama S.-H., Yasui Y., Ohmori S., Tanaka W., and Hirano H.-Y.
    • Journal Title

      Plant Cell Physiol.

      Volume: 印刷中 Issue: 6 Pages: 1284-1295

    • DOI

      10.1093/pcp/pcz020

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] WUSCHEL-RELATED HOMEOBOX4 acts as a key regulator in early leaf development in rice2018

    • Author(s)
      Yasui, Y., Ohmori, Y., Takebayashi, Y., Sakakibara, H., and Hirano, H.-Y.
    • Journal Title

      PLOS Genetics

      Volume: 14 Issue: 4 Pages: e1007365-e1007365

    • DOI

      10.1371/journal.pgen.1007365

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Two-color in situ hybridization: a technique for simultaneous detection of each transcript from different loci.2018

    • Author(s)
      Toriba, T. and Hirano, H.Y.
    • Journal Title

      “Plant transcription factor”

      Volume: -

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Characterization of a <i>half-pipe-like leaf1</i> mutant that exhibits a curled leaf phenotype2017

    • Author(s)
      Hikari Matsumoto, Yukiko Yasui, Toshihiro Kumamaru, and Hiro-Yuki Hirano
    • Journal Title

      Genes & Genetic Systems

      Volume: 92 Issue: 6 Pages: 287-291

    • DOI

      10.1266/ggs.17-00013

    • NAID

      130006731265

    • ISSN
      1341-7568, 1880-5779
    • Year and Date
      2017-12-01
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] イネの腋芽形成を開始する遺伝的機構2020

    • Author(s)
      田中若奈, 平野博之
    • Organizer
      日本植物生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Elongated complex の最大サブユニットをコードする CURLED LATER1 はイネの特定の成長段階における葉の発生に必要である2020

    • Author(s)
      松本 光梨, 安居 佑季子, 大森 良弘,田中 若奈,石川 哲也, 沼 寿隆,白澤 健太,谷口 洋二郎,田中 淳一,鈴木 保宏,平野 博之
    • Organizer
      日本植物生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 2 次シュート形成に異常を生じるイネ変異体 tiller elongation defective1 (ted1) に関する発生遺伝学的解析2020

    • Author(s)
      並木愛海, 平野博之, 田中若奈
    • Organizer
      日本植物生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] イネの発生を制御する Elongator 遺伝子の機能解析2020

    • Author(s)
      松本光梨, 安居佑季子, 大森良弘,田中若奈,石川哲也, 沼寿隆,白澤健太,谷口洋二郎,田中淳一,鈴木保宏,平野博之
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Meristem maintenance and inflorescence development in rice2019

    • Author(s)
      Hiro-Yuki Hirano
    • Organizer
      Plant Stem Cells: Source of Plant Vitality, Workshop1: Stem cells and Plant Reproduction
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Genetic regulation of stem cell maintenance during axillary bud formation in rice2019

    • Author(s)
      Wakana Tanaka
    • Organizer
      Plant Stem Cells: Source of Plant Vitality, Workshop1: Stem cells and Plant Reproduction
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 個体の成長とともに葉の形態を変化させるイネ変異体の発生遺伝学的解析2019

    • Author(s)
      松本 光梨, 安居 佑季子, 石川 哲也,鈴木 保宏,平野 博之
    • Organizer
      イネ遺伝学・分子生物学ワークショップ2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 分げつが形成されないイネ突然変異体に関する発生遺伝学的解析2019

    • Author(s)
      並木愛海, 平野博之, 田中若奈
    • Organizer
      イネ遺伝学・分子生物学ワークショップ2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 小穂形成に異常があるイネ突然変異体の解析2019

    • Author(s)
      大森涼葉, 川上直人, 平野博之, 田中若奈
    • Organizer
      イネ遺伝学・分子生物学ワークショップ2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] イネの腋芽形成における WOX および KNOX 遺伝子の働き2019

    • Author(s)
      田中若奈, 津田勝利,平野博之
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 個体の成長にともなって葉の形態を制御するイネ遺伝子の発生遺伝学的解析2019

    • Author(s)
      松本光梨, 安居佑季子, 田中若奈,大森良弘,石川哲也, 沼寿隆,白澤健太,谷口洋二郎,田中淳一,鈴木保宏,平野博之
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 分げつ形成に異常を生じるイネ変異体 tiller elongation defective1 (ted1) に関する発生遺伝学的解析2019

    • Author(s)
      並木愛海, 平野博之, 田中若奈
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] イネ tillers absent1 変異体は小穂に多面的な異常を示す2019

    • Author(s)
      大森涼葉, 川上直人, 平野博之, 田中若奈
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 個体の成長にともない葉の形態異常が生じるイネ 変異体の原因遺伝子の探索2019

    • Author(s)
      鈴木保宏, 沼寿隆, 白澤健太, 谷口 洋二郎, 松本 光梨, 安居 佑季子, 石川 哲也, 平野博之, 田中淳一
    • Organizer
      日本育種学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 多面的アプローチによるイネの進化遺伝学的研究2019

    • Author(s)
      平野博之
    • Organizer
      日本遺伝学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] イネの腋芽幹細胞の確立と維持機構2019

    • Author(s)
      田中若奈, 平野博之
    • Organizer
      日本植物生理学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] イネの幹細胞維持を制御するFON signaling と転写抑制因子ASP1の機能解析2019

    • Author(s)
      鈴木 千絵,田中 若奈,平野 博之
    • Organizer
      日本植物生理学会
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Presentation] イネの腋芽形成過程における幹細胞維持の制御メカニズム2019

    • Author(s)
      田中 若奈, 平野 博之
    • Organizer
      日本育種学会
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Presentation] イネの花序構築を制御するBELL1型ホメオボックス遺伝子RIとRIL1の機能解析2019

    • Author(s)
      池田 拓之, 田中 若奈, 鳥羽 大陽, 鈴木 千絵,前野 哲輝, 津田 勝利, 城石 俊彦, 倉田 哲也, 坂本 智昭, 村井 正之, 松坂 弘明, 熊丸 敏博, 平野 博之
    • Organizer
      日本育種学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 個体の成長にともない葉の形態異常が生じるイネ変異体の発生学的解析2019

    • Author(s)
      松本 光梨, 安居 佑季子, 石川 哲也,鈴木 保宏,平野 博之
    • Organizer
      日本育種学会
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Presentation] イネの腋芽幹細胞の確立と維持機構2019

    • Author(s)
      田中 若奈, 平野 博之
    • Organizer
      日本植物生理学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] イネの遺伝と進化 --お米の品質,トランスポゾン,形態形成から考える--2019

    • Author(s)
      平野博之
    • Organizer
      日本メンデル協会 キトロギア創刊90周年記念講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 異形葉性を示すイネ変異体の発生遺伝学的解析2018

    • Author(s)
      松本 光梨, 安居 佑季子, 石川 哲也,鈴木 保宏,平野 博之
    • Organizer
      日本遺伝学会
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Presentation] イネの分げつ形成不全変異体に関する遺伝学的解析2018

    • Author(s)
      並木愛海, 田中若奈, 平野博之
    • Organizer
      日本育種学会
    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Presentation] イネのブランチ形成における幹細胞制御因子の分子遺伝学的解析2018

    • Author(s)
      田中 若奈, 平野 博之
    • Organizer
      日本遺伝学会
    • Related Report
      2017 Annual Research Report
  • [Book] 花の分子発生遺伝学2018

    • Author(s)
      平野 博之、阿部 光知
    • Total Pages
      224
    • Publisher
      裳華房
    • ISBN
      9784785358686
    • Related Report
      2017 Annual Research Report
  • [Remarks] 進化遺伝学研究室ホームページ

    • URL

      http://www.bs.s.u-tokyo.ac.jp/&#631;hirano/English.html

    • Related Report
      2019 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

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