Development of core collocation in garlic genetic resources through integrated omics analysis and its evaluation for functionality
| Project/Area Number |
17H03766
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Horticultural science
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
澤田 有司 国立研究開発法人理化学研究所, 環境資源科学研究センター, 客員研究員 (00415176)
山田 朋宏 国立研究開発法人農業・食品産業技術総合研究機構, 野菜花き研究部門, ユニット長 (50391412)
佐藤 修正 東北大学, 生命科学研究科, 准教授 (70370921)
小林 誠 山口大学, 大学院医学系研究科, 教授 (80225515)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2019: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2017: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Keywords | ニンニク / オミクス統合解析 / 遺伝資源 / コアコレクション / SNP / 園芸学 / 育種学 / ゲノム / 植物 / 農林水産物 |
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| Outline of Final Research Achievements |
Our research via the use of unique genetic resources was carried out enable a holistic approach to profile the phytochemical composition as well as its related gene expression of alliums for functional material studies, through collaborative development of resources for metabolomics-high throughput chemical profiling by mass spectrometry, together with transcriptomics assay metadata by RNA-Seq. The metabolomics analysis of worldwide germplasm collection in garlic (Allium sativum L.) proved to be effective in evaluating its genetic diversity. Our main focus was to select useful food and/or medical materials amongst the mapping various genotypes and phenotypes. An omics approach could be utilized to characterize variation in these genetic stocks, developing capability and plant materials to support metabolomics-informed plant breeding studies.
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| Academic Significance and Societal Importance of the Research Achievements |
中央アジアに由来する稔性系統を含む，我々の研究グループが保有するニンニク遺伝資源は世界各地から収集した変異に富むものである．本研究の成果により，これらの遺伝資源は数々の有用変異を有するバイオリソースとしてニンニクの遺伝学や育種に広く利用でき，重要な研究用リソースと成り得ることが証明された．特に，メタボローム解析を通じて，将来的に健康食材や医薬原料となる系統が見出されており，農業生産分野に止まらず広くライフサイエンス分野への科学的貢献が見込める成果として今後の研究の進展が期待される．
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Report
(4 results)
Research Products
(6 results)
