Search for novel functionalities of rice endosperm protein/bran protein and analysis of their mechanisms
| Project/Area Number |
17H03816
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Niigata Institute of Technology (2018-2019)
Niigata University (2017) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
久保田 真敏 新潟工科大学, 工学部, 准教授 (00595879)
藤村 忍 新潟大学, 自然科学系, 教授 (20282999)
|
|---|
| Project Period (FY) |
2017-04-01 – 2020-03-31
|
| Project Status |
Completed (Fiscal Year 2019)
|
| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2019: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2018: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
|
|---|
| Keywords | 米タンパク質 / 生活習慣病 / 肥満 / ミネラル・骨代謝異常 / アレルギー |
|---|
| Outline of Final Research Achievements |
In order to discover the novel functionalities of rice, proteins from rice endsperm (REP) and rice bran (RBP) were investigated to show the following significant effects for health. REP and RBP were shown to suppress the obesity, body weight gain and some adipose tissue weight, in C57BL/6 mice fed with a high fat diet. By using type 2 diabetic ZDF rats, RBP showed to alleviate deterioration of bone microstructures and bone strength of diabetic rats. Finally, by using BALB/c mice, REP showed the induction of skewing toward Th1, and the suppression of total blood IgE and antigen-specific IgE concentrations, indicating anti-allergic property.
|
| Academic Significance and Societal Importance of the Research Achievements |
米は我が国で唯一の自給可能な穀物であり、長らく食料自給率の維持に貢献してきた。けれども、その消費量は近年、減少の一途を辿り、現在ではピーク時から半減している。そこで、米の魅力として、美味しさに加えて健康に対する機能性を新たに発掘することができれば、米に対する消費者の意識は大きく変わり、消費量の増加を期待することができる。これはすなわち、我が国の農業、そして食料自給率の改善に大きく寄与することは間違いない。
|
Report
(4 results)
Research Products
(17 results)
-
-
-
[Journal Article] Rice bran protein ameliorates diabetes, reduces fatty liver, and has renoprotective effects in Zucker Diabetic Fatty rats2020
Author(s)
Masatoshi Kubota, Reiko Watanabe, Michihiro Hosojima, Akihito Saito, Ai Sasou, Takehiro Masumura, Yukikazu Harada, Hiroyuki Hashimoto, Shinobu Fujimura, Motoni Kadowaki
-
Journal Title
Journal of Functional Foods
Volume: 70
Pages: 103981-103981
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Beneficial effects of rice endosperm protein on chronic kidney disease-mineral and bone disorder (CKD-MBD) in Zucker diabetic fatty rats2017
Author(s)
Reiko Watanabe, Masatoshi Kubota, Shogo Sugaki, Michihiro Hosojima, Akihiko Saito, Mikio Fujii, Ichiro Sasagawa, Shinobu Fujimura, Motoni Kadowaki
Organizer
International Congress of Nutrition (IUNS 21th ICN, Buenos Aires, Argentina)
Related Report
Int'l Joint Research
-
-
-
