Molecular analysis of brain plasticity in diapause inducton of the silkworm
| Project/Area Number |
17H03941
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Insect science
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| Research Institution | Shinshu University |
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Principal Investigator |
Shiomi Kunihiro 信州大学, 学術研究院繊維学系, 教授 (70324241)
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| Co-Investigator(Kenkyū-buntansha) |
溝口 明 愛知学院大学, 教養部, 教授 (60183109)
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| Project Period (FY) |
2017-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2020: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2019: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2018: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | 休眠 / 温度センサー / カイコ / クワコ / 時計因子 / カイコ (Bombyx mori) / 脳可塑性 / 季節適応 |
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| Outline of Final Research Achievements |
Diapause is a common response to seasonal changes in environmental conditions found in many species of insects as well as other animals, but we do not yet fully understand the molecular mechanisms underlying this important physiological switch in Bombyx mori. Our research highlighted the presence of a GABAergic and corazonin signaling system that induces progeny diapause through diapause hormone release. Furthermore, we performed a comparative analysis between the Kosetsu strain of B. mori and a Japanese population of the wild mulberry silkworm B. mandarina concerning the hierarchical molecular mechanisms in diapause induction. We hypothesize that TRPA1-activated signals are strongly linked to the signaling pathway participating in diapause induction in Kosetsu to selectively utilize the temperature information as the cue because temperature-dependent induction was replaced by photoperiodic induction in the TRPA1 knockout mutant.
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| Academic Significance and Societal Importance of the Research Achievements |
昆虫をはじめとする生物の環境応答機構における分子機構の解明として意義があるばかりか，蚕糸科学やカイコが家畜化された過程を探る上で非常に重要な研究成果となりうる。
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Report
(5 results)
Research Products
(26 results)
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[Book] カイコの科学2020
Author(s)
日本蚕糸学会
Total Pages
224
Publisher
朝倉書店
ISBN
4254420439
Related Report
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