| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2019: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2018: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2017: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
|
|---|
| Outline of Final Research Achievements |
Fibrosis is a condition characterized by excess production of extracellular matrix components, such as collagens, in tissues, and can greatly reduce the function of various organs by hardening the tissues. Fibrosis of tissues is carried out by a group of cells called myofibroblasts which produce matrix proteins, such as collagens. Myofibroblasts are rarely present when tissues are normal, but arise from a variety of cells in response to events, such as inflammation. We identified a marker receptor that is specifically expressed in myofibroblasts in the heart, lung, and liver.
|
