Development of new dimensional clinical neuroimaging method based on the waste clearance system of inner ear

• Project/Area Number: 17H04259
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Nagoya University
• Principal Investigator: Naganawa Shinji 名古屋大学, 医学系研究科, 教授 (50242863)
• Co-Investigator(Kenkyū-buntansha): 渡辺 宏久 藤田医科大学, 医学部, 教授 (10378177) ; 曽根 三千彦 名古屋大学, 医学系研究科, 教授 (30273238) ; 田岡 俊昭 名古屋大学, 医学系研究科, 特任教授 (30305734)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000); Fiscal Year 2019: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2018: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
• Keywords: 血液迷路関門 / 血液脳脊髄液関門 / 血液脳関門 / 磁気共鳴画像 / ガドリニウム造影剤 / 内リンパ水腫 / メニエール病 / Glymphatic system / 血管周囲腔

Outline of Final Research Achievements

We have developed new MR pulse sequences that have extremely high sensitivity to low concentration gadolinium based contrast agent. Then we applied them to the patients with the suspicion of endolymphatic hydrops in the inner ear. We found and reported that the leakage of gadolinium to cerebrospinal fluid around cortical veins in the patients older than 37-years-old. As we accumulate many patients' data, we experienced some exceptional cases who shows leakage from younger period. Also we experienced the subjects without leakage in oldr subjects. We exnamined 190 cases, finally, we could find the cut-off value of 37.3-years-old from the receiver operating curve analysis. We have published this result on the journal "Magnetic Resonance in Medical Sciences". These results are gathering many attentions from neuroscience community as the objective biomaker of brain aging.

Academic Significance and Societal Importance of the Research Achievements

人類にとって大きな問題である認知症などの神経変性疾患の謎に脳と内耳の老廃物排泄機構の面から迫った。我々が開発した磁気共鳴画像パルスシーケンスを使用して、ガドリニウム造影剤が重大な疾患がなくても脳脊髄液へ少量漏出することが明らかとなり、それが37.3歳という年齢を境に急速に増加することがわかった。皮質静脈周囲の潜在的な軟膜に囲まれたスペースが排泄機構の一部であり、脳のリンパ管である髄膜リンパ管に連続していることを示唆する画像所見も発表できた。これらの結果から、長年ベールに包まれていた脳の老廃物排泄機構の一端を解明することができ、客観的なバイオマーカーとしても使用できる可能性を示せた。

Research Products

• [Int'l Joint Research] バイエル中央研究所(ドイツ)
• [Int'l Joint Research] University of Navarre(スペイン)
• [Journal Article] The Space between the Pial Sheath and the Cortical Venous Wall May Connect to the Meningeal Lymphatics (2020)
  • Author(s): Shinji Naganawa, Rintaro Ito, Toshiaki Taoka, Tadao Yoshida, Michihiko Sone
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 1 Pages: 1-4
  • DOI: 10.2463/mrms.bc.2019-0099
  • NAID: 130007796227
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Detection of IV-gadolinium Leakage from the Cortical Veins into the CSF Using MR Fingerprinting (2020)
  • Author(s): Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka, Hirokazu Kawaguchi, Katsuya Maruyama, Katsutoshi Murata, Gregor Korzdorfer, Josef Pfeuffer, Mathias Nittka, Michihiko Sone
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 2 Pages: 141-146
  • DOI: 10.2463/mrms.mp.2019-0048
  • NAID: 130007839522
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Glymphatic imaging using MRI. (2020)
  • Author(s): Toshiaki Taoka, Shinji Naganawa
  • Journal Title: J Magn Reson Imaging. Volume: 51(1) Issue: 1 Pages: 11-24
  • DOI: 10.1002/jmri.26892
  • NAID: 120006884950
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive Evaluation of B₁⁺-corrected FISP-based Magnetic Resonance Fingerprinting: Accuracy, Repeatability and Reproducibility of T₁ and T₂ Relaxation Times for ISMRM/NIST System Phantom and Volunteers (2020)
  • Author(s): Yutaka Kato, Kazushige Ichikawa, Kuniyasu Okudaira, Toshiaki Taoka, Hirokazu Kawaguchi, Katsutoshi Murata, Katsuya Maruyama, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, Shinji Naganawa
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 3 Pages: 168-175
  • DOI: 10.2463/mrms.mp.2019-0016
  • NAID: 130007884317
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Quantification of Endolymphatic Space Volume after Intravenous Administration of a Single Dose of Gadolinium-based Contrast Agent: 3D-real Inversion Recovery versus HYDROPS-Mi2 (2020)
  • Author(s): Toshio Ohashi, Shinji Naganawa, Ai Takeuchi, Toshio Katagiri, Kayao Kuno
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 2 Pages: 119-124
  • DOI: 10.2463/mrms.mp.2019-0013
  • NAID: 130007839529
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] White matter microstructural changes in tuberous sclerosis: Evaluation by neurite orientation dispersion and density imaging (NODDI) and diffusion tensor images. (2020)
  • Author(s): Toshiaki Taoka, Noriko Aida, Yuta Fujii, Kazushi Ichikawa, Hisashi Kawai, Toshiki Nakane, Rintaro Ito, Shinji Naganawa
  • Journal Title: SCIENTIFIC REPORTS Volume: 10 Issue: 1 Pages: 436-436
  • DOI: 10.1038/s41598-019-57306-w
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of newly implemented dose calculation algorithms for multileaf collimator-based CyberKnife tumor-tracking radiotherapy. (2020)
  • Author(s): Kohei Kawata, Takeshi Kamomae, Hiroshi Oguchi, Fumitaka Kawabata, Kuniyasu Okudaira, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
  • Journal Title: Med Phys Volume: 47 Issue: 3 Pages: 1391-1403
  • DOI: 10.1002/mp.14013
  • Peer Reviewed / Open Access
• [Journal Article] Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics (2020)
  • Author(s): Roshani Perera, Haruo Isoda, Kenta Ishiguro, Takashi Mizuno, Yasuo Takehara, Masaki Terada, Chiharu Tanoi, Takehiro Naito, Harumi Sakahara, Hisaya Hiramatsu, Hiroki Namba, Takashi Izumi, Toshihiko Wakabayashi, Takafumi Kosugi, Yuki Onishi, Marcus Alley, Yoshiaki Komori, Mitsuru Ikeda, Shinji Naganawa
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 4 Pages: 333-344
  • DOI: 10.2463/mrms.mp.2019-0107
  • NAID: 130007948918
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Optimal Plane Selection for Measuring Post-prandial Blood Flow Increase within the Superior Mesenteric Artery: Analysis Using 4D Flow and Computational Fluid Dynamics (2020)
  • Author(s): Masataka Sugiyama, Yasuo Takehara, Masanori Kawate, Naoki Ooishi, Masaki Terada, Haruo Isoda, Harumi Sakahara, Shinji Naganawa, Kevin M. Johnson, Oliver Wieben, Tetsuya Wakayama, Atsushi Nozaki, Hiroyuki Kabasawa
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 4 Pages: 366-374
  • DOI: 10.2463/mrms.mp.2019-0089
  • NAID: 130007948909
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent (2020)
  • Author(s): Shinji Naganawa, Rintaro Ito, Hisashi Kawai, Toshiaki Taoka, Tadao Yoshida, Michihiko Sone
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 19 Issue: 4 Pages: 375-381
  • DOI: 10.2463/mrms.mp.2019-0182
  • NAID: 130007948896
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of segment 4 portal vein embolization added to right portal vein for right hepatic trisectionectomy: A retrospective propensity score‐matched study (2020)
  • Author(s): Ito Jun、Komada Tomohiro、Suzuki Kojiro、Matsushima Masaya、Nakatochi Masahiro、Kobayashi Yumiko、Ebata Tomoki、Naganawa Shinji、Nagino Masato
  • Journal Title: Journal of Hepato-Biliary-Pancreatic Sciences Volume: N.A. Issue: 6 Pages: 299-306
  • DOI: 10.1002/jhbp.723
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy and safety of accelerated fractionated radiotherapy without elective nodal irradiation for T3N0 glottic cancer without vocal cord fixation. (2020)
  • Author(s): Masayuki Okumura, Atsushi Motegi, Sadamoto Zenda, Naoki Nakamura, Hidehiro Hojo, Masaki Nakamura, Yasuhiro Hirano, Shun-Ichiro Kageyama, Satoko Arahira, Raturi Vijay Parshuram, Hirofumi Kuno, Ryuichi Hayashi, Makoto Tahara, Yoshiyuki Itoh , Shinji Naganawa, Tetsuo Akimoto
  • Journal Title: Head Neck. Volume: - Issue: 8 Pages: 1775-1782
  • DOI: 10.1002/hed.26092
  • Peer Reviewed / Open Access
• [Journal Article] Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol. (2020)
  • Author(s): Hiroyasu Umakoshi, Takashi Nihashi, Hironori Shimamoto, Takehiro Yamada, Hiroaki Ishiguchi, Akira Takada, Naoki Hirasawa, Shunichi Ishihara, Yasuo Takehara, Shinji Naganawa, Matthew Davenport, Teruhiko Terasawa,
  • Journal Title: BMJ Open. Volume: 10(3) Issue: 3 Pages: e033023-e033023
  • DOI: 10.1136/bmjopen-2019-033023
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Age Dependence of Gadolinium Leakage from the Cortical Veins into the Cerebrospinal Fluid Assessed with Whole Brain 3D-real Inversion Recovery MR Imaging (2019)
  • Author(s): Naganawa S, Nakane T, Kawai H, Taoka T.
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 18 Issue: 2 Pages: 163-169
  • DOI: 10.2463/mrms.mp.2018-0053
  • NAID: 130007630075
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Celebrating the beginning of international journal collaboration. (2019)
  • Author(s): Shinji Naganawa, Yukunori Korogi
  • Journal Title: Jpn J Radiol. Volume: 38(1) Issue: 1 Pages: 1-2
  • DOI: 10.1007/s11604-019-00904-5
  • Peer Reviewed / Open Access
• [Journal Article] Increased signal intensity of low-concentration gadolinium contrast agent by longer repetition time in heavily T(2)-weighted-3D-FLAIR. (2019)
  • Author(s): Kato Y, Bokura K, Taoka T, Naganawa S.
  • Journal Title: Jpn J Radiol. Volume: 38 Issue: 5 Pages: 431-435
  • DOI: 10.1007/s11604-019-00828-0
  • NAID: 50014127809
  • Peer Reviewed / Open Access
• [Journal Article] A case of human pancreatic eurytremiasis. (2019)
  • Author(s): Hiroshi Ogawa, Yasuo Takehara, Shinji Naganawa, Junpei Yamaguchi, Masato Nakaguro
  • Journal Title: Abdom Radiol (NY) Volume: 44(4) Issue: 4 Pages: 1213-1216
  • DOI: 10.1007/s00261-019-01925-4
  • Peer Reviewed / Open Access
• [Journal Article] Utility of Metabolic Parameters on FDG PET/CT in the Classification of Early-Stage Lung Adenocarcinoma: Prediction of Pathological Invasive Size (2019)
  • Author(s): Iwano S, et al.
  • Journal Title: Clin Nucl Med Volume: 44 Issue: 7 Pages: 560-565
  • DOI: 10.1097/rlu.0000000000002591
  • Peer Reviewed / Open Access
• [Journal Article] Postoperative Recurrence of Clinical Early-Stage Non-Small Cell Lung Cancers: A Comparison Between Solid and Subsolid Nodules (2019)
  • Author(s): Iwano S, et al.
  • Journal Title: Cancer Imaging Volume: 19 Issue: 1 Pages: 33-33
  • DOI: 10.1186/s40644-019-0219-3
  • Peer Reviewed / Open Access
• [Journal Article] Balloon-Occluded Retrograde Transvenous Obliteration for Fundal Gastric Variceal Bleeding in a Small Child. (2019)
  • Author(s): Tomohiro Komada, Kojiro Suzuki, Kazuo Oshima, Masaya Matsushima, Ken Nagasaka, Shinji Naganawa
  • Journal Title: J Vasc Interv Radiol. Volume: 30(10) Issue: 10 Pages: 1624-1625
  • DOI: 10.1016/j.jvir.2019.06.022
  • Peer Reviewed / Open Access
• [Journal Article] Reorganization of brain networks and its association with general cognitive performance over the adult lifespan. (2019)
  • Author(s): Epifanio Bagarinao, Hirohisa Watanabe, Satoshi Maesawa, Daisuke Mori, Kazuhiro Hara, Kazuya Kawabata, Noritaka Yoneyama, Reiko Ohdake,…他 Haruo Isoda, Shinji Naganawa, Gen Sobue
  • Journal Title: Sci Rep. Volume: 9(1) Issue: 1 Pages: 11352-11352
  • DOI: 10.1038/s41598-019-47922-x
  • Peer Reviewed / Open Access
• [Journal Article] A plea for systematic literature analysis and conclusive study design, comment on: "Systematic review of magnetic resonance imaging for diagnosis of Meniere disease". (2019)
  • Author(s): Robert Gurkov, Krisztina Barath, Bert de Foer, Munehisa Fukushima, Michael Gluth, Jermy Hornibrook, Nicolas Perez-Fernandez, Ilmari Pyykko, Michihiko Sone, Shin-Ichi Usami, Wuqing Wang, Jing Zou, Shinji Naganawa
  • Journal Title: J Vestib Res. Volume: - Issue: 2 Pages: 151-157
  • DOI: 10.3233/ves-190662
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Large expert-curated database for benchmarking document similarity detection in biomedical literature search. (2019)
  • Author(s): Peter Brown, RELISH Consortium, Yaoqi Zhou,…RELISH consortium (Shinji Naganawa)
  • Journal Title: DATABASE (The Journal of Biological Databeses and Curation) Volume: - Pages: 085-085
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] High-dose-rate intracavitary brachytherapy for recurrent cervical cancer in the vaginal stump after hysterectomy (2019)
  • Author(s): Yuka Kozai, Yoshiyuki Itoh, Mariko Kawamura, Rie Nakahara, Junji Ito, Tohru Okada, Fumitaka Kikkawa, Mitsuru Ikeda, Shinji Naganawa
  • Journal Title: Nagoya Journal of Medical Science Volume: 81 Issue: 3 Pages: 351-358
  • DOI: 10.18999/nagjms.81.3.351
  • NAID: 120006716063
  • ISSN: 2186-3326
  • URL: https://nagoya.repo.nii.ac.jp/records/28452
  • Peer Reviewed / Open Access
• [Journal Article] Phase II study of chemoradiotherapy combined with gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic ductal adenocarcinoma (NUPAT 05 Trial): study protocol for a single arm phase II study (2019)
  • Author(s): Nao Takano, Suguru Yamada, Akihiro Hirakawa, Yukihiro Yokoyama, Hiroki Kawashima, Osamu Maeda, …他 Shinji Naganawa, Yuichi Ando, Masato Nagino, Hidemi Goto, Tsutomu Fujii, Yasuhiro Kodera
  • Journal Title: Nagoya Journal of Medical Science Volume: 81 Issue: 2 Pages: 233-239
  • DOI: 10.18999/nagjms.81.2.233
  • NAID: 120006643303
  • ISSN: 2186-3326
  • URL: https://nagoya.repo.nii.ac.jp/records/28241
  • Peer Reviewed / Open Access
• [Journal Article] Whole abdominopelvic intensity-modulated radiation therapy for peritoneal disseminated rhabdomyosarcoma with three-year follow-up: a case report. (2019)
  • Author(s): Mariko Kawamura, Kuniyasu Okudaira, Yoshiyuki Itoh, Takeshi Kamomae, Eri Nishikawa, Hideki Muramatsu, Yoshiyuki Takahashi, Kazuki Yokota, Shinji Naganawa
  • Journal Title: Radiat Oncol. Volume: 14(1) Issue: 1 Pages: 127-127
  • DOI: 10.1186/s13014-019-1333-x
  • Peer Reviewed / Open Access
• [Journal Article] Monitoring of fatigue in radiologists during prolonged image interpretation using fNIRS. (2019)
  • Author(s): Takashi Nihashi, Takeo Ishigaki, Hiroko Satake, Shinji Ito, Osamu Kaii, Yoshine Mori, Kazuhiro Shimamoto, Hiromichi Fukushima, Kojiro Suzuki, Hiroyasu Umakoshi, Mitsuo Ohashi, Fumio Kawaguchi, Shinji Naganawa
  • Journal Title: Jpn J Radiol. Volume: 37(6) Issue: 6 Pages: 437-448
  • DOI: 10.1007/s11604-019-00826-2
  • Peer Reviewed / Open Access
• [Journal Article] Can low b value diffusion weighted imaging evaluate the character of cerebrospinal fluid dynamics? (2019)
  • Author(s): Taoka, T; Naganawa, S; Kawai, H; Nakane, T; Murata, K
  • Journal Title: JAPANESE JOURNAL OF RADIOLOGY Volume: 37 Issue: 2 Pages: 135-144
  • DOI: 10.1007/s11604-018-0790-8
  • NAID: 210000164484
  • Peer Reviewed / Open Access
• [Journal Article] Inter-individual Comparison of Gadobutrol and Gadoteridol Tissue Time-intensity Profiles for Dynamic Susceptibility Contrast Perfusion MR Imaging (2019)
  • Author(s): Yamada, M; Taoka, T; Kawaguchi, A; Yasuda, K; Niinomi, Y; Ohashi, Y; Okuda, T; Naganawa, S
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 18 Issue: 1 Pages: 75-81
  • DOI: 10.2463/mrms.mp.2017-0172
  • NAID: 130007555395
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Signal Intensity of the Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agents: Strong Contrast Enhancement around the Vein of Labbe. (2019)
  • Author(s): Toshio Ohashi, Shinji Naganawa, Eriko Ogawa, Toshio Katagiri, Kayao Kuno
  • Journal Title: Magn Reson Med Sci. Volume: - Issue: 3 Pages: 194-199
  • DOI: 10.2463/mrms.mp.2018-0043
  • NAID: 130007679749
  • Peer Reviewed / Open Access
• [Journal Article] Improved 3D-real Inversion Recovery: A Robust Imaging Technique for Endolymphatic Hydrops after Intravenous Administration of Gadolinium (2019)
  • Author(s): Shinji Naganawa, Hisashi Kawai, Toshiaki Taoka, Michihiko Sone
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 18 Issue: 1 Pages: 105-108
  • DOI: 10.2463/mrms.bc.2017-0158
  • NAID: 130007555348
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Clinical MR imaging of endolymphatic hydrops: Updates on scanning methods, image processing and interpretation. (2018)
  • Author(s): Shinji Naganwa
  • Journal Title: Solutions in Contrast Imaging. Volume: 9(5) Pages: 1-5
  • Peer Reviewed
• [Journal Article] Diagnostic Radiology Service in Japan. (2018)
  • Author(s): Shinji Naganawa, Yukunori Korogi
  • Journal Title: Japanese Journal of Radiology. Volume: 36(10) Issue: 10 Pages: 575-578
  • DOI: 10.1007/s11604-018-0770-z
  • Peer Reviewed / Open Access
• [Journal Article] Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer. (2018)
  • Author(s): Suguru Yamada, Tsutomu Fujii, Yukihiro Yokoyama, Hiroki Kawashima, Osamu Maeda, Kojiro Suzuki, Tohru Okada, Eizaburo Ono, Junpei Yamaguchi, Nao Takano, Hideki Takami, Masamichi Hayashi, Yukiko Niwa, Yoshiki Hirooka, Yoshiyuki Ito, Shinji Naganawa, Yuichi Ando, Masato Nagino, Hidemi Goto, Yasuhiro Kodera
  • Journal Title: Cancer Chemother Pharmacol. Volume: 81(5) Issue: 5 Pages: 815-821
  • DOI: 10.1007/s00280-018-3554-3
  • Peer Reviewed / Open Access
• [Journal Article] Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer’s Disease: A PET (THK5351, PiB) and Resting fMRI Study (2018)
  • Author(s): Yokoi Takamasa、Watanabe Hirohisa、Ishigaki Shinsuke、Katsuno Masahisa、Miyao Shinichi、Kato Katsuhiko、Naganawa Shinji、Harada Ryuichi、Okamura Nobuyuki、Yanai Kazuhiko、Yoshida Mari、Sobue Gen （ほか9名）
  • Journal Title: Frontiers in Aging Neuroscience Volume: 10 Pages: 304-304
  • DOI: 10.3389/fnagi.2018.00304
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy of percutaneous transhepatic portal vein embolization using gelatin sponge particles and metal coils. (2018)
  • Author(s): Tomohiro Komada, Kojiro Suzuki, Takashi Mizuno, Tomoki Ebata, Masaya Matsushima, Shinji Naganawa, Masato Nagino
  • Journal Title: Acta Radiol Open. Volume: 7(4) Issue: 4
  • DOI: 10.1177/2058460118769687
  • Peer Reviewed / Open Access
• [Journal Article] Effects of Gradient Coil Noise and Gradient Coil Replacement on the Reproducibility of Resting State Networks (2018)
  • Author(s): Bagarinao Epifanio、Tsuzuki Erina、Yoshida Yukina、Ozawa Yohei、Kuzuya Maki、Otani Takashi、Koyama Shuji、Isoda Haruo、Watanabe Hirohisa、Maesawa Satoshi、Naganawa Shinji、Sobue Gen
  • Journal Title: Frontiers in Human Neuroscience Volume: 12 Pages: 148-148
  • DOI: 10.3389/fnhum.2018.00148
  • Peer Reviewed / Open Access
• [Journal Article] Corpus callosal involvement is correlated with cognitive impairment in multiple system atrophy. (2018)
  • Author(s): Hara K, Watanabe H, Bagarinao E, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Tsuboi T, Ito M, Atsuta N, Niwa H, Taoka T, Maesawa S, Naganawa S, Katsuno M, Sobue G.
  • Journal Title: J Neurol. Volume: 265 Issue: 9 Pages: 2079-2087
  • DOI: 10.1007/s00415-018-8923-7
  • Peer Reviewed / Open Access
• [Journal Article] Prediction of Intracranial Arterial Stenosis Progression in Patients with Moyamoya Vasculopathy: Contrast-Enhanced High-Resolution Magnetic Resonance Vessel Wall Imaging (2018)
  • Author(s): Muraoka, S; Araki, Y; Taoka, T; Kawai, H; Okamoto, S; Uda, K; Ota, S; Naganawa, S; Wakabayashi, T
  • Journal Title: WORLD NEUROSURGERY Volume: 116 Pages: e1114-e1121
  • DOI: 10.1016/j.wneu.2018.05.181
  • Peer Reviewed / Open Access
• [Journal Article] Impact of the Glymphatic System on the Kinetic and Distribution of Gadodiamide in the Rat Brain (2018)
  • Author(s): Taoka Toshiaki、Jost Gregor、Frenzel Thomas、Naganawa Shinji、Pietsch Hubertus
  • Journal Title: Investigative Radiology Volume: 53 Issue: 9 Pages: 1-1
  • DOI: 10.1097/rli.0000000000000473
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Longitudinal Findings of MRI and PET in West Syndrome with Subtle Focal Cortical Dysplasia. (2018)
  • Author(s): Y. Sakaguchi, H. Kidokoro, C. Ogawa, Y. Okai, Y. Ito, H. Yamamoto, A. Ohno, T. Nakata, T. Tsuji, T. Nakane, H. Kawai, K. Kato, Shinji Naganawa, J. Natsume
  • Journal Title: AJNR Am J Neuroradiol. Volume: 39(10) Issue: 10 Pages: 1932-1937
  • DOI: 10.3174/ajnr.a5772
  • Peer Reviewed / Open Access
• [Journal Article] Significance of Endolymphatic Hydrops Herniation Into the Semicircular Canals Detected on MRI. (2018)
  • Author(s): Satofumi Sugimoto, Tadao Yoshida, Masaaki Teranishi, Masumi Kobayashi, Mariko Shimono, Shinji Naganawa, Michihiko Sone
  • Journal Title: Otol Neurotol. Volume: 39(10) Issue: 10 Pages: 1932-1937
  • DOI: 10.1097/mao.0000000000002022
  • Peer Reviewed / Open Access
• [Journal Article] Predictive factors for the outcomes of initial I-131 low-dose ablation therapy to Japanese patients with differentiated thyroid cancer. (2018)
  • Author(s): Shinji Ito, Shingo Iwano, Katsuhiko Kato, Shinji Naganawa
  • Journal Title: Ann Nucl Med. Volume: 32(6) Issue: 6 Pages: 418-424
  • DOI: 10.1007/s12149-018-1261-0
  • Peer Reviewed / Open Access
• [Journal Article] Study Protocol: Prospective Study of Concurrent Chemoradiotherapy with S-1 and Hypofractionated Radiotherapy for Outpatients with Early Glottic Squamous Cell Carcinomas. (2018)
  • Author(s): Kana Kimura, Yoshiyuki Itoh, Tohru Okada, Seiji Kubota, Mariko Kawamura, Rie Nakahara, Yumi Oie, Yuka Kozai, Yuuki Takase, Hidenori, Tsuzuki, Naoki Nishio, Mariko Hiramatsu, Yasushi Fujimoto, Takefumi Mizutani, Akihiro Hirakawa, Shinji Naganawa
  • Journal Title: Asian Pac J Cancer Prev. Volume: 19(5) Pages: 1195-1199
  • Peer Reviewed / Open Access
• [Journal Article] Diagnostic performance of 18F-FDG PET/CT and whole-body diffusion-weighted imaging with background body suppression(DWIBS) in detection of lymph node and bone metastases from pediatric neuroblastoma. (2018)
  • Author(s): Hiroaki Ishiguchi, Shinji Ito, Katsuhiko Kato, Yusuke Sakurai, Hisashi Kawai, Naotoshi Fujita, Shinji Abe, Atsushi Narita, Nobuhiro Nishio, Hideki Muramatsu, Yoshiyuki Takahashi, Shinji Naganawa
  • Journal Title: Ann Nucl Med. Volume: 32(5) Issue: 5 Pages: 348-362
  • DOI: 10.1007/s12149-018-1254-z
  • Peer Reviewed / Open Access
• [Journal Article] Myocardial motion analysis based on an optical flow method using tagged MR images. (2018)
  • Author(s): Daiki Tabata, Haruo Isoda, Kaori Kato, Hiroki Matsubara, Takafumi Kosugi, Takashi Kosugi, Masaki Terada, Atsushi Fukuyama, Yoshiaki Komori, Shinji Naganawa
  • Journal Title: Radiol Phys Technol. Volume: 11(2) Issue: 2 Pages: 202-211
  • DOI: 10.1007/s12194-018-0456-3
  • Peer Reviewed / Open Access
• [Journal Article] Histogram analysis of quantitative pharmacokinetic parameters on DCE-MRI: correlations with prognostic factors and molecular subtypes in breast cancer. (2018)
  • Author(s): Ken Nagasaka, Hiroko Satake, Satoko Ishigaki, Hisashi Kawai, Shinji Naganawa
  • Journal Title: Breast Cancer. Volume: 26(1) Issue: 1 Pages: 113-124
  • DOI: 10.1007/s12282-018-0899-8
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of late adverse events and their chronological changes after radiation therapy for cervical cancer (2018)
  • Author(s): Takehiro Yamada, Shunichi Ishihara, Michiyasu Kawai, Yoshiyuki Itoh, Shinji Naganawa, Mitsuru Ikeda
  • Journal Title: Nagoya Journal of Medical Science Volume: 80 Issue: 4 Pages: 487-496
  • DOI: 10.18999/nagjms.80.4.487
  • NAID: 120006549154
  • ISSN: 2186-3326
  • URL: https://nagoya.repo.nii.ac.jp/records/27021
  • Peer Reviewed / Open Access
• [Journal Article] Significance of internal auditory canal diverticula in ears with otosclerosis. (2018)
  • Author(s): Fei Wang, Tadao Yoshida, Satofumi Sugimoto, Masaaki Teranishi, Shinji Naganawa, Michihiko Sone
  • Journal Title: Acta Otolaryngol. Volume: 138(12) Issue: 12 Pages: 1066-1069
  • DOI: 10.1080/00016489.2018.1521526
  • Peer Reviewed / Open Access
• [Journal Article] Differences in Signal Intensity and Enhancement on MR Images of the Perivascular Spaces in the Basal Ganglia versus Those in White Matter (2018)
  • Author(s): Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 17 Issue: 4 Pages: 301-307
  • DOI: 10.2463/mrms.mp.2017-0137
  • NAID: 130007496649
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Relationship between Contrast Enhancement of the Perivascular Space in the Basal Ganglia and Endolymphatic Volume Ratio (2018)
  • Author(s): Toshio Ohashi, Shinji Naganawa, Toshio Katagiri, Kayao Kuno
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 17 Issue: 1 Pages: 67-72
  • DOI: 10.2463/mrms.mp.2017-0001
  • NAID: 130006306826
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Gadolinium-based Contrast Media, Cerebrospinal Fluid and the Glymphatic System: Possible Mechanisms for the Deposition of Gadolinium in the Brain (2018)
  • Author(s): Toshiaki Taoka, Shinji Naganawa
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 17 Issue: 2 Pages: 111-119
  • DOI: 10.2463/mrms.rev.2017-0116
  • NAID: 130006685586
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] An unbiased data-driven age-related structural brain parcellation for the identification of intrinsic brain volume changes over the adult lifespan. (2018)
  • Author(s): Bagarinao E
  • Journal Title: Neuroimage. Volume: 169 Pages: 134-144
  • DOI: 10.1016/j.neuroimage.2017.12.014
  • Peer Reviewed / Open Access
• [Journal Article] Lack of Contrast Enhancement in a Giant Perivascular Space of the Basal Ganglion on Delayed FLAIR Images: Implications for the Glymphatic System (2017)
  • Author(s): Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 16 Issue: 2 Pages: 89-90
  • DOI: 10.2463/mrms.ci.2016-0114
  • NAID: 130005589284
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Improved HYDROPS: Imaging of Endolymphatic Hydrops after Intravenous Administration of Gadolinium (2017)
  • Author(s): Shinji Naganawa, Hisashi Kawai, Toshiaki Taoka, Michihiko Sone,
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 16 Issue: 4 Pages: 357-361
  • DOI: 10.2463/mrms.tn.2016-0126
  • NAID: 130006163852
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Letter to Editors: Detection of endolymphatic hydrops using traditional MR imaging sequences. (2017)
  • Author(s): Shinji Naganawa, Michihiko Sone
  • Journal Title: Am J Otolaryngol. Volume: 38(5) Issue: 5 Pages: 637-638
  • DOI: 10.1016/j.amjoto.2017.06.014
  • Peer Reviewed
• [Journal Article] CSF Pulsation Artifacts on ADC Maps Obtained with Readout-segmented EPI (2017)
  • Author(s): Toshio Ohashi, Shinji Naganawa, Mai Kanou, Mitsuru Ikeda
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 16 Issue: 2 Pages: 123-128
  • DOI: 10.2463/mrms.mp.2016-0031
  • NAID: 130005589293
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Letter to the editor on the article Saccular measurements in routine MRI can predict hydrops in Meniere's disease by Simon F et al. (2017)
  • Author(s): Pablo Dominguez, Shinji Naganawa
  • Journal Title: Eur Arch Otorhinolaryngol. Volume: 275(1) Issue: 1 Pages: 311-312
  • DOI: 10.1007/s00405-017-4794-2
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer’s disease cases. (2017)
  • Author(s): Taoka T, Masutani Y, Kawai H, Nakane T, Matsuoka K, Yasuno F, Kishimoto T, Naganawa S.
  • Journal Title: Jpn J Radiol Volume: 35 Issue: 4 Pages: 172-178
  • DOI: 10.1007/s11604-017-0617-z
  • NAID: 120006323685
  • Peer Reviewed / Open Access
• [Journal Article] Significance of Endolymphatic Hydrops in Ears With Unilateral Sensorineural Hearing Loss. (2017)
  • Author(s): Yuriko Okazaki, Tadao Yoshida, Satofumi Sugimoto, Masaaki Teranishi, Ken Kato, Shinji Naganawa, Michihiko Sone
  • Journal Title: Otol Neurotol. Volume: 38(8) Issue: 8 Pages: 1076-1080
  • DOI: 10.1097/mao.0000000000001499
  • Peer Reviewed
• [Journal Article] Longitudinal Up-Regulation of Endolymphatic Hydrops in Patients with Meniere’s Disease During Medical Treatment. (2017)
  • Author(s): Munehisa Fukushima, Tadashi Kitahara, Ryohei Oya, Shiro Akahani, Hidenori Inohara, Shinji Naganawa, Noriaki Takeda
  • Journal Title: Laryngoscope Investigative Otolaryngology Volume: 2(6) Issue: 6 Pages: 344-350
  • DOI: 10.1002/lio2.115
  • Peer Reviewed
• [Journal Article] The Relationship Between Endolymphatic Hydrops in the Vestibule and Low-Frequency Air-Bone Gaps. (2017)
  • Author(s): Satofumi Sugimoto, Tadao Yoshida, Masaaki Teranishi, Yuriko Okazaki, Shinji Naganawa, Michihiko Sone
  • Journal Title: Laryngoscope. Volume: Epub ahead of print Issue: 7 Pages: 1658-1662
  • DOI: 10.1002/lary.26898
  • Peer Reviewed
• [Journal Article] Detecting sub-second changes in brain activation patterns during interictal epileptic spike using simultaneous EEG-fMRI (2017)
  • Author(s): Epifanio Bagarinao, Satoshi Maesawa, Yuji Ito, Naotaka Usui, Jun Natsume, Hirohisa Watanabe, Minoru Hoshiyama, Toshihiko Wakabayashi, Gen Sobue, Shinji Naganawa, Haruo Isoda
  • Journal Title: Clin Neurophysiol. Volume: 129(2) Issue: 2 Pages: 377-389
  • DOI: 10.1016/j.clinph.2017.11.018
  • Peer Reviewed / Open Access
• [Journal Article] Penetration and distribution of gadolinium-based contrast agents into the cerebrospinal fluid in healthy rats: a potential pathway of entry into the brain tissue (2016)
  • Author(s): Gregor Jost, Thomas Frenzel, Jessica Lohrke, Diana Constanze Lenhard, Shinji Naganawa, Hubertus Pietsch
  • Journal Title: Eur Radiol. Volume: - Issue: 7 Pages: 2877-2885
  • DOI: 10.1007/s00330-016-4654-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] 肝原発MALTリンパ腫の2例 (2020)
  • Author(s): 西田あゆみ、兵藤良太、岩野信吾、下山芳江、長縄慎二
  • Organizer: 第87回東海総合画像医学研究会
• [Presentation] 乳房専用PETにおける正常乳腺のFDG集積に対する閉経の有無と月経周期の影響 (2020)
  • Author(s): 清水友理、佐竹弘子、石垣聡子、長縄慎二、田所匡典、石口恒男
  • Organizer: 日本医学放射線学会第167回中部地方会
• [Presentation] IGBT導入に向けたコンツール制度の検証： high volume centerでの導入に向けて (2020)
  • Author(s): 川村麻里子、伊藤善之、大宝和博、伊藤淳二、中原理絵、大家祐実、香西由加、髙瀬裕樹、加茂前健、長縄慎二
  • Organizer: 日本医学放射線学会第167回中部地方会
• [Presentation] Meniere disease imaging: What is right, what is wrong, what is new (2019)
  • Author(s): Shinji Naganawa
  • Organizer: The 32nd Annual Meeting of the European Society of Head and Neck Radiology (eshnr 2019)
  • Int'l Joint Research / Invited
• [Presentation] Influence of implanted metals in new CT reconstruction algorithm for radiotherapy treatment planning. (2019)
  • Author(s): Takeshi Kamomae, Takayoshi Nakaya, Fumitaka Kawabata, Kuniyasu Okudaira, Motoki Kumagai, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: European Society for Therapeutic Radiology and Oncology (ESTRO38)
  • Int'l Joint Research
• [Presentation] The impact of shorter acquisition time in MRF: Long term repeatability and reproducibility study on ISMRM/NIST phantom and volunteers. (2019)
  • Author(s): Yutaka Kato, Kazushige Ichikawa, Toshiaki Taoka, Hirokazu Kawaguchi, Katsutoshi Murata, Katsuya Maruyama, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, Shinji Naganawa
  • Organizer: International Society for Magnetic Resonance in Medicine 27th Annual Meeting (27th ISMRM)
  • Int'l Joint Research
• [Presentation] Low b-value diffusion weighted imaging to evaluate cerebrospinal fluid dynamics. (2019)
  • Author(s): Toshiaki Taoka, Shinji Naganawa, Hisashi Kawai, Toshiki Nakane, Katsutoshi Murata
  • Organizer: International Society for Magnetic Resonance in Medicine 27th Annual Meeting (27th ISMRM)
  • Int'l Joint Research
• [Presentation] Evaluation of 223Ra therapy on bone metastases of prostate cancer by 18F-fluoride PET/CT, 18F-FDG PET/CT and bone scintigraphy/SPECT (2019)
  • Author(s): Katsuhiko Kato, Tetsuro Odagawa, Naotoshi Fujita, Yoshinori Tsutsumi, Shinji Abe, Shinji Naganawa
  • Organizer: Society of Nuclear Medicine & Molecular Imaging 2019 Annual Meeting
  • Int'l Joint Research
• [Presentation] Development of Three-Dimensional Printed Compensator for Improvement of Dose Distribution in Boron Neutron Capture Therapy: A Preliminary Study (2019)
  • Author(s): Takeshi Kamomae, Yoshinori Sakurai, Masataka Oita, Takushi Takata, Tatsuya Niimi, Takashi Matsumura, Takuya Saito, Tomohiro Komada, Katsuhiko Kato, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 61st American Association of Physicists in Medicine Annual Meeting
  • Int'l Joint Research
• [Presentation] An attempt to create a hollow blood vessel model by direct inkjet 3D printing with nano-composite hydrogel for IR. (2019)
  • Author(s): Tomohiro Komada, Takeshi Kamomae, Takashi Matsumura, Takuya Saito, Tatsuya Niimi, Masaya Matsushima, Ryota Hyodo, Shinji Naganawa
  • Organizer: Cardiovascular and Interventional Radiological Society of Europe 2019
  • Int'l Joint Research
• [Presentation] Should Small Cell Carcinoma of the Cervix be Treated As Localized Small Cell Cancer or Advanced Cervical Cancer: A Retrospective Multi-Institutional Cohort Study (2019)
  • Author(s): Mariko Kawamura, Yutaro Koide, Taro Murai, Shunichi Ishihara, Yuuki Takase, Takayuki Murao, Dai Okazaki, Takahiro Yamaguchi, Kaoru Uchiyama, Yoshiyuki Itoh, Takeshi Kodaira, Yuta Shibamoto, Mika Mizuno, Fumitaka Kikkawa, Shinji Naganawa
  • Organizer: American Society for Radiation Oncology 2019(ASTRO 2019)
  • Int'l Joint Research
• [Presentation] Clinical results of T1 glottic cancer treated with radiotherapy using 2.25 Gy per fractions：A multicenter survey in clinical practice. (2019)
  • Author(s): Yumi Oie,Yoshiyuki Itoh, Mariko Kawamura, Yuki Takase, Takayuki Murano, Shunichi Ishihara, Yoshihito Nomoto, naoki Hirasawa, Akiko Asano, Kouji Yamakawa, Junji Ito, Shinji Naganawa
  • Organizer: American Society for Radiation Oncology 2019(ASTRO 2019)
  • Int'l Joint Research
• [Presentation] MR Fingerprinting Evaluation for the Early Changes of Relaxation Time in the Brain Tumor and Surrounding White Matter After Stereotactic Radiotherapy. (2019)
  • Author(s): Toshiaki Taoka, Kazuhiro Ohtakara, Hisashi Kawai, Yutaka Kato, Yoshiyuki Itoh, Shinji Naganawa, Toshiki Nakane, Rintaro Ito, Kazushige Ichikawa, Kuniyasu Okudaira, Katsutoshi Murata, Katsuya Maruyama, Hirokazu Kawaguchi, Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka
  • Organizer: 105th Scientific Assembly and Annual Meeting of Radiological Society of North America(RSNA)
  • Int'l Joint Research
• [Presentation] Gadolinium Deposition in the Brain and Glymphatic System (2019)
  • Author(s): Toshiaki Taoka, Rintaro Ito, Rei Nakamichi, Toshiki Nakane, Hisashi Kawai, Shinji Naganawa
  • Organizer: 105th Scientific Assembly and Annual Meeting of Radiological Society of North America(RSNA)
  • Int'l Joint Research
• [Presentation] Invited Lecture 10の司会 (2019)
  • Author(s): 長縄慎二
  • Organizer: 第78回日本医学放射線学会総会
• [Presentation] MR imaging of endolymphatic hydrops; What is right, what is wrong, and what is new. (2019)
  • Author(s): 長縄慎二
  • Organizer: 第21回山形めまい研究会
• [Presentation] 特別講演Ⅱ 脳の老廃物排泄機構とMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 第11回お茶の水 Neuroimaging Conference-ONIC-
• [Presentation] Glymphatic systemとMRI造影剤 (2019)
  • Author(s): 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Glymphatic systemとMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 第99回慶應医学会総会・シンポジウム
• [Presentation] 特別講演 Glymphatic SystemとMRI (2019)
  • Author(s): 長縄慎二
  • Organizer: 画論 27th The Best Image
• [Presentation] Novel electron density based-CT image from single-and dual-energy scanning for radiation therapy treatment planning. (2019)
  • Author(s): Takeshi Kamomae, Fumitaka Kawabata, Takayoshi Nakaya, Kuniyasu Okudaira, Motoki Kumagai, Yoshikazu Miyake, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 第117回日本医学物理学会学術大会
• [Presentation] Comparison single treatment planning and multiple planning for multiple targets in Cyberknife therapy. (2019)
  • Author(s): Motoki Kumagai, Kazuhiro Ohtakara, Takeshi Kamomae, Fumitaka Kawabata, Kuniyasu Okudaira, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 第117回日本医学物理学会学術大会
• [Presentation] 感染契機の肺動脈仮性動脈瘤からの喀血に対し塞栓術を施行した1例 A case of embolization for hemoptysis due to an infectious pulmonary artery pseudoaneurysm. (2019)
  • Author(s): 山田恵一郎、兵藤良太、堀口瞭太、伊藤 準、松島正哉、駒田智大、長縄慎二、進藤有一郎、長坂 憲
  • Organizer: 第48回日本IVR学会総会
• [Presentation] 舌骨下やリンパ節へのI-131集積は分化型甲状腺癌患者に対する低用量アブレーションの成否に影響するか） (2019)
  • Author(s): 伊藤信嗣、岩野信吾、長縄慎二、加藤克彦
  • Organizer: 日本核医学会 第89回中部地方会
• [Presentation] 肝内門脈静脈短絡に対し塞栓術を施行した2例 (2019)
  • Author(s): 松島正哉、駒田智大、山田恵一郎、堀口瞭太、伊藤 準、兵藤良太、岩野信吾、長縄慎二、石津洋二、田中 卓、馬越弘泰
  • Organizer: 第66回中部IVR研究会
• [Presentation] 術前診断が困難であった膵lymphangiomaの1例 (2019)
  • Author(s): 小川 浩、竹原康雄、長縄慎二、高見秀樹、中黒匡人
  • Organizer: 日本医学放射線学会第166回中部地方会
• [Presentation] 早期乳癌に対する乳房温存手術＋術中放射線部分照射：10年の結果 (2019)
  • Author(s): 川村麻里子、伊藤善之、大宝和博、岡田 徹、伊藤淳二、大家祐実、加茂前健、長縄慎二
  • Organizer: 日本医学放射線学会第166回中部地方会
• [Presentation] 中枢神経系原発anaplastic lymphoma kinase陽性未分化大細胞リンパ腫の1例 (2019)
  • Author(s): 佐々木裕太郎、中道玲瑛、川井 恒、田岡俊昭、長縄慎二、川島直実、下山芳江
  • Organizer: 第86回東海総合画像医学研究会
• [Presentation] 7テスラMR装置の高空間分解能3次元位相コントラスト磁気共鳴法を利用した脳血流動態解析の精度検証 (2019)
  • Author(s): 田嶋駿亮、礒田治夫、福永雅喜、小森芳秋、Roshani Perera、水野 崇、定藤規弘、長縄慎二
  • Organizer: 第86回東海総合画像医学研究会
• [Presentation] 腹部大動脈に対するEndovascular Aneurysmal Repairは内臓動脈の血流を増加させる(4D-Flowによる血行動態解析) (2019)
  • Author(s): 杉山将隆、竹原康雄、堀口瞭太、兵藤良太、駒田智大、長縄慎二、礒田治夫、牛尾貴輔、五島 聡、若山哲也、野崎 敦、Marcus Alley
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 健常者とEVAR術前後の腹部大動脈瘤患者のEnergy Loss (2019)
  • Author(s): 水野 崇、竹原康雄、杉山将隆、堀口瞭太、長縄慎二、櫻井康雄、加藤 裕、阿部真治、礒田治夫、佐藤智宏、石口恒男、田所匡典、野崎 敦
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 腹部大動脈瘤に対するステントグラフト内挿術(EVAR) (2019)
  • Author(s): 堀口瞭太、竹原康雄、杉山将隆、兵藤良太、駒田智大、松島正哉、川井 恒、長縄慎二、水野 崇、櫻井康雄、阿部真治、小森芳秋
  • Organizer: 第1回 4D-Flow研究会
• [Presentation] 定位放射線治療後の組織緩和時間のMRFによる測定：標的領域と周辺領域の評価 MR fingerprinting evaluation for the early changes of relaxation time in the target area and surrounding area after stereotactic radiotherapy. (2019)
  • Author(s): 田岡俊昭、大宝和博、川井 恒、中根俊樹、伊藤倫太郎、加藤 裕、市川和茂、奥平訓康、伊藤善之、川口浩和、村田勝俊、丸山克也、 Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Evaluation of number of iterations for reconstruction in VIBE with compressed sensing on ultrafast dynamic breast MR Compressed sensing VIBE法を用いた乳房ultrafast MRIにおけるiteration回数による画質への影響 (2019)
  • Author(s): 河村美奈子、加藤 裕、奥平訓康、佐竹弘子、丸山克也、長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] Impact of step size in the dictionary for long T1 values on MR Fingerprinting MR Fingerprintingにおけるステップ幅の異なる辞書による定量値への影響 (2019)
  • Author(s): 熊澤智宇、加藤 裕、市川和茂、田岡俊昭、村田勝俊、丸山克也、Gregor Koerzdoerfer, Josef Pfeuffer, Mathias Nittka, 長縄慎二
  • Organizer: 第47回日本磁気共鳴医学会大会
• [Presentation] 分化型甲状腺癌の術後アブレーションにおける予期せぬトレーサー集積部位の検討 (2019)
  • Author(s): 岩野信吾、伊藤信嗣、伊藤倫太郎、神谷晋一朗、加藤克彦、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Presentation] 舌骨下やリンパ節へのI-131集積は低用量アブレーションの成否に影響するか (2019)
  • Author(s): 伊藤信嗣、岩野信吾、加藤克彦、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Presentation] 18F-NaF PET/CT、18F-FDG PET/CT、骨シンチ/SPECTによる去勢抵抗性前立腺癌骨転移223Ra治療の評価 (2019)
  • Author(s): 加藤克彦、小田川哲郎、藤田尚利、堤 貴紀、田村美香、阿部真治、長谷川 千夏、長縄慎二
  • Organizer: 日本核医学会第59回学術集会
• [Presentation] AI(Artificial intelligence)と画像診断～世界の潮流をふまえて～ (2019)
  • Author(s): 長縄慎二
  • Organizer: European Conference of Radiology (ECR) 2019
  • Int'l Joint Research
• [Presentation] Assessment of the severity in chronic thromboembolic pulmonary hypertension by quantitative parameters of dual-energy CT. (2019)
  • Author(s): Yoshinori Tsutsumi, Shingo Iwano, Naoki Okumura, Shiro Adachi, Shinji Abe, Takahisa Kondo, Shinji Naganawa, Katsuhiko Kato
  • Organizer: European Conference of Radiology (ECR) 2019
  • Int'l Joint Research
• [Presentation] Prediction of pathologic responses to neoadjuvant chemotherapy and prognosis in patients with locally advanced rectal cancer using perfusion computed tomography. (2019)
  • Author(s): Satoko Ishigaki, Takashi Nihashi, Hiroko Satake, Keisuke Uehara, Shinji Naganawa
  • Organizer: European Conference of Radiology (ECR) 2019
  • Int'l Joint Research
• [Presentation] Evaluation of haemodynamic and morphological biomarkers to assess the rupture risk of intracranial aneurysms using magnetic resonance fluid dynamics and computational fluid dynamics. (2019)
  • Author(s): Roshani Perera, Haruo Isoda, Shunsuke Tajima, Takashi Mizuno, Masaki Terada, Takehiro Naito, Chiharu Tanoi, Takashi Izumi, Yasuo Takehara, Toshihiko Wakabayashi, Harumi Sakahara, Shinji Naganawa
  • Organizer: 第85回東海総合画像医学研究会
• [Presentation] MR Fingerprintingによる放射線治療前後の組織緩和時間の変化：T1緩和時間、T2緩和時間同時定量の意義 (2019)
  • Author(s): 田岡俊昭、大宝和博、川井 恒、中根俊樹、加藤 裕、川口宏和、丸山克也、村田勝俊、Nittka Mathias、伊藤善之、長縄慎二
  • Organizer: 第48回日本神経放射線学会
• [Presentation] 7テスラMR装置の高空間分解能3次元位相コントラスト磁気共鳴法を利用した脳血流動態解析の精度検証 (2019)
  • Author(s): 田嶋駿亮、礒田治夫、福永雅喜、小森芳秋、水野 崇、定藤規弘、長縄慎二
  • Organizer: 第48回日本神経放射線学会
• [Presentation] Leakage of IV-gadolinium to CSF; Where does it from? (2018)
  • Author(s): Shinji Naganawa
  • Organizer: German-Japanese Radiological Affilication 19th Workshop
  • Int'l Joint Research
• [Presentation] Glymphatic system:State of the art science (2018)
  • Author(s): Shinji Naganawa
  • Organizer: AIMS Neuroimaging in Chicago 2018
  • Int'l Joint Research
• [Presentation] Impact of the glymphatic system on the kinetric and distribution of gadodiamide in the rat brain: Observation by dynamic MRI and effect of circadian rhythm on tissue gadolinium concentrations. (2018)
  • Author(s): Toshiaki Taoka、Gregor Jost, Shinji Naganawa, Hubertus Pietsch
  • Organizer: International Society for Magnetic Resonance in Medicine 2018(ISMRM 2018)
  • Int'l Joint Research
• [Presentation] Blood flow measurement using 3D cine PC MRI within the abdominal aortic aneurysm and visceral arteries in pre- and post-EVAR condition; blood flow in the SMA might be improved after EVAR. (2018)
  • Author(s): Masataka Sugiyama, Yasuo Takehara, Tetsuya Wakayama, Atsushi Nozaki, Marcus Alley, Takasuke Ushio, Shinji Naganawa, Harumi Sakahara
  • Organizer: International Society for Magnetic Resonance in Medicine 2018(ISMRM 2018)
  • Int'l Joint Research
• [Presentation] A Matched Study Comparing Right Portal Vein Embolization with and without Segment 4 Portal Vein Embolization for Right Hepatic Trisectionectomy. (2018)
  • Author(s): Jun Ito, Tomohiro Komada, Masahiro Nakatochi, Fumie Kinoshita, Yumiko Kobayashi, Kojiro Suzuki, Shinji Naganawa
  • Organizer: 104th Scientific Assembly and Annual Meeting of Radiological Society of North America(RSNA)
  • Int'l Joint Research
• [Presentation] Feasibility of novel thin bolus using tungsten functional paper for electron beam radiotherapy. (2018)
  • Author(s): Takeshi Kamomae, Hajime Monzen, Kazuma Sugita, Kuniyasu Okudaira, Morikazu Amano, Yoshihiro Kawai, Hiroshi Oguchi, Motoki Kumagai, Mariko Kawamura, Kazuhiro Ohtakara, Yoshiyuki Itoh, Shinji Naganawa
  • Organizer: 18th Asia-Oceania Congress of Medical Physics (AOCMP) & 16th South-East Asia Congress of Medical Physics (SEACOMP)
  • Int'l Joint Research
• [Presentation] 診断教授の教室での放射線治療専門医の育成 (2018)
  • Author(s): 長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] 論文執筆は楽しい (2018)
  • Author(s): 長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] キャノンMRIの新しい幕開け (2018)
  • Author(s): 長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] Glymphatic system仮説とMRI：最近の動向 Glymphatic system hypothesis and MR imaging: Recent status (2018)
  • Author(s): 長縄慎二
  • Organizer: 第46回日本磁気共鳴医学会大会
• [Presentation] Glymphatic system 仮説とMRI (2018)
  • Author(s): 長縄慎二
  • Organizer: 第37回日本認知症学会学術集会
• [Presentation] 人工知能と画像診断 (2018)
  • Author(s): 長縄慎二
  • Organizer: 名古屋大学脳とこころの研究センター市民公開講座 「目指せ！健康脳：最新の診断、予防、治療」
• [Presentation] Glymphatic system hypothesis and MR imaging: Implication for Endolymphatic hydrops, diffusion and gadolinium deposition in brain. (2018)
  • Author(s): Shinji Naganawa
  • Organizer: 第3回国際磁気共鳴医学会 日本支部年次学術集会
• [Presentation] 脳内の老廃物排出システム(Glymphatic system)と脳内ガドリニウム沈着 (2018)
  • Author(s): 田岡俊昭、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] 交連線維方向の拡散に注目した拡散によるGlymphatic系の評価 (2018)
  • Author(s): 田岡俊昭、増谷佳孝、川井 恒、中根俊樹、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] UICC8版に基づく臨床病期Ⅰ期肺癌の予後評価 (2018)
  • Author(s): 岩野信吾、馬越弘泰、神谷晋一朗、伊藤倫太郎、島本宏矩、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] 乳腺混合性腫瘤の画像所見：USとMRIを中心に (2018)
  • Author(s): 石垣聡子、佐竹弘子、林 葉子、松本篤子、角田伸行、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] すりガラス影を有する肺癌における充実成分の3D容積計測と予後との相関 (2018)
  • Author(s): 神谷晋一朗、岩野信吾、馬越弘泰、伊藤倫太郎、島本宏矩、中村彰太、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] Superficial Learning about "Deep Learning":What Radiologists Should Know (2018)
  • Author(s): 伊藤倫太郎、岩野信吾、長縄慎二
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] 膵管内乳頭粘液性腫瘍との鑑別が困難であった膵蛭（すいてつ） 症の1例 (2018)
  • Author(s): 小川 浩、竹原康雄、長縄慎二、山口淳平、下山芳江
  • Organizer: 第77回日本医学放射線学会総会
• [Presentation] 分枝膵管を主体とするITPN（intraductal tubulopapillary neoplasm）の1例 (2018)
  • Author(s): 堀口瞭太、小川 浩、竹原康雄、長縄慎二、山口淳平、下山 芳江
  • Organizer: 第32回日本腹部放射線学会
• [Presentation] 分化型甲状腺癌術後患者に対するⅠ-131アブレーション―血中サイログロブリン高値を示す患者へのⅠ-131高用量投与は推奨されるか (2018)
  • Author(s): 伊藤信嗣、岩野信吾、長縄慎二、加藤克彦
  • Organizer: 日本核医学会第87回中部地方会
• [Presentation] コンピュータ支援診断によるPart-solid肺癌の容積計測：充実成分容積は予後を予測する (2018)
  • Author(s): 神谷晋一朗、岩野信吾、馬越弘泰、伊藤倫太郎、島本宏矩、中村彰太、長縄慎二
  • Organizer: SAMI 2018
• [Presentation] フローダイバーター設置後に周囲脳動脈に経時的に血流動態変化を来した大型内頸動脈流の1例 (2018)
  • Author(s): 田嶋駿亮、礒田治夫、泉 孝嗣、塚田哲也、櫻井康雄、長縄慎二
  • Organizer: 第84回東海総合画像医学研究会
• [Presentation] 淡明細胞乳頭状腎細胞癌の2例 (2018)
  • Author(s): 山田恵一郎、松島正哉、長縄慎二、後藤百万、都筑豊徳
  • Organizer: 第84回東海総合画像医学研究会
• [Presentation] Evaluating the dynamics of cerebrospinal fluid using low b-value diffusion weighted images: Septum pellucidum in dilated ventricle 低b値拡散強調像による脳脊髄液動態評価の試み: 脳室拡張と透明中隔 (2018)
  • Author(s): 田岡俊昭、川井 恒、中根俊樹、長縄慎二
  • Organizer: 第46回日本磁気共鳴医学会大会
• [Presentation] Tissue correlation time mapping by MR fingerprinting: Evaluation in normal brain MR fingerprinting法を用いた組織相関時間画像：正常脳での検討 (2018)
  • Author(s): 田岡俊昭、川井 恒、中根俊樹、川口浩和、丸山克也、村田勝年、Gregor Koerzdoerfer、Jisef Pfeuffer、Mathias Nittka、酒井晃二、山田 惠、長縄慎二
  • Organizer: 第46回日本磁気共鳴医学会大会
• [Presentation] Evaluation of the internal thalamic structure on MP2RAGE by the texture analysis テクスチャー解析を用いたMP2RAGEでの視床内部構造の評価 (2018)
  • Author(s): 中根俊樹、田岡俊昭、川井 恒、加藤 裕、櫻井康雄、丸山克也、長縄慎二
  • Organizer: 第46回日本磁気共鳴医学会大会
• [Presentation] 低ｂ値（ｂ=500ｓ/m㎡)拡散強調像による脳脊髄駅動態の評価 (2018)
  • Author(s): 田岡俊昭、長縄慎二、川井 恒、中根俊樹
  • Organizer: 第8回生理学研究所・名古屋大学医学系研究科合同シンポジウム
• [Presentation] 放射線抵抗性子宮頸癌の半導体レーザによる温熱機器の開発とその実用化 (2018)
  • Author(s): 伊藤善之、香西由加、木村香菜、川村麻里子、中原理絵、大家祐実、髙瀬裕樹、奥村真之、伊藤淳二、岡田 徹、大宝和博、長縄慎二、山田啓一郎、中村誠司
  • Organizer: 日本放射線腫瘍学会第31回学術大会
• [Presentation] 腹膜播種を伴う横紋筋肉腫に対しIMRTを用いて全腹腔照射行った１例 (2018)
  • Author(s): 川村麻里子、奥平訓康、伊藤善之、大宝和博、岡田 徹、中原理絵、 伊藤淳二、大家祐実、木村香菜、髙瀬裕樹、長縄慎二
  • Organizer: 日本放射線腫瘍学会第31回学術大会
• [Presentation] 早期声門癌に対するS-1併用化学放射線治療の成績 (2018)
  • Author(s): 髙瀬裕樹、木村香菜、伊藤善之、大宝和博、岡田 徹、川村麻里子、伊藤淳二、中原理絵、大家祐実、香西由加、藤本保志、長縄慎二
  • Organizer: 日本放射線腫瘍学会第31回学術大会
• [Presentation] 4D Flow MRIによる腎動脈上・下腹部大動脈における反射波の影響の差についての検討、逆流方向の血流の比較 (2018)
  • Author(s): 杉山将隆、竹原康雄、大石直樹、若山哲也、野崎 敦、Marcus Alley、牛尾貴補、長縄慎二、阪原晴海
  • Organizer: 第3回国際磁気共鳴医学会 日本支部年次学術集会
• [Presentation] Gd presence in the brain: impact of daytime and anaesthesia. (2018)
  • Author(s): Toshiaki Taoka, G. Jost, Shinji Naganawa, H. Pietsch
  • Organizer: European Congress of Radiology 2018 (ECR)
  • Int'l Joint Research
• [Presentation] SNR Plenary Lecture「Glymphatic System and MR Imaging: Implication for Endolymphatic」 (2018)
  • Author(s): Shinji Naganawa
  • Organizer: The 12th Asian-Oceanian Congress of Neuroradiology
  • Int'l Joint Research / Invited
• [Presentation] Texture analysis of low grade glioma: differential diagnosis between diffuse astrocytoma and oligodendroglioma. (2018)
  • Author(s): Hisashi Kawai, Toshiaki Taoka, Toshiki Nakane, Yasuo Sakurai, Shinji Naganawa
  • Organizer: The 12th Asian-Oceanian Congress of Neuroradiology
  • Int'l Joint Research
• [Presentation] Glymphatic system仮説とMRI；最近の動向 (2018)
  • Author(s): 長縄慎二
  • Organizer: 第47回日本神経放射線学会
• [Presentation] ラット脳内ガドリニウム沈着における概日リズムおよび麻酔の影響 (2018)
  • Author(s): 田岡俊昭、Gregor Jost、長縄慎二、Hubertus Pietsch
  • Organizer: 第47回日本神経放射線学会
• [Presentation] How Does Gd Enter the Brain, When the BBB is Intact? (2017)
  • Author(s): Shinji Naganawa
  • Organizer: International Society for Magnetic Resonance in Medicine 2017(ISMRM 2017)
  • Int'l Joint Research / Invited
• [Presentation] Evaluating Glymphatic System by Diffusion Images: Alzheimer's Disease Cases Analyzed by Diffusion Tensor Image Analysis Along Perivascular Space(DTI-ALPS). (2017)
  • Author(s): Toshiaki Taoka, Yoshitaka Masutani, Hisashi Kawai, Toshiki Nakane, Kiwamu Matsuoka, Fumihiko Yasuno, Shinji Naganawa
  • Organizer: International Society for Magnetic Resonance in Medicine 2017(ISMRM 2017)
  • Int'l Joint Research
• [Presentation] Delayed FLAIRでの迷路信号の左右非対称 (2017)
  • Author(s): 長縄慎二、川井 恒、中根俊樹、田岡俊昭、曽根三千彦
  • Organizer: 第76回日本医学放射線学会総会
• [Presentation] Tract based DTI-ALPS法によるアルツハイマー病症例でのGlymphatic system評価の試み (2017)
  • Author(s): 田岡俊昭、増谷佳孝、川井 恒、中根俊樹、長縄慎二
  • Organizer: 第76回日本医学放射線学会総会
• [Presentation] Glymphatic SystemとMRI (2017)
  • Author(s): 長縄慎二
  • Organizer: 第63回九州MRI研究会
• [Remarks] 名古屋大学医学部放射線医学教室ホームページ
  • URL: https://www.med.nagoya-u.ac.jp/rad/
• [Remarks] 名古屋大学脳とこころの研究センターホームページ
  • URL: https://www.med.nagoya-u.ac.jp/noutokokoro/
• [Remarks] 名古屋大学医学部放射線医学教室
  • URL: https://www.med.nagoya-u.ac.jp/rad/