Development of care bundle for preventing wound infection based on bedside biofilm detection
| Project/Area Number |
17H04455
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gerontological nursing
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Nakagami Gojiro 東京大学, 大学院医学系研究科(医学部), 准教授 (70547827)
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| Co-Investigator(Kenkyū-buntansha) |
真田 弘美 東京大学, 大学院医学系研究科(医学部), 教授 (50143920)
峰松 健夫 東京大学, 大学院医学系研究科(医学部), 特任准教授 (00398752)
須釜 淳子 金沢大学, 新学術創成研究機構, 教授 (00203307)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2019: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | バイオフィルム / ブロッティング / デブリードマン / 緑膿菌 / 褥瘡 / 糖尿病足潰瘍 / 異分野融合 / ポイントオブケア / 超音波デブリードマン / 可視化 / 慢性創傷 / 看護理工学 / クオラムセンシング |
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| Outline of Final Research Achievements |
The detection of biofilm as a cause of pressure ulcer infection has been based on invasive and time-consuming methods such as tissue biopsy. The limited availability of biofilm examinations made clinical observation impossible. In this study, we have developed a non-invasive, point-of-care bedside biofilm detection technology. We visualize the biofilm using blotting membrane applied to a wound and stained for a very short time. We have confirmed the concurrent and predictive validity of biofilm detection methods (animal studies, clinical studies). The implementation of a wound care system based on the results of biofilm detection at the bedside could significantly accelerate wound healing in chronic wounds. The system is currently on the market as a biofilm detection tool.
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| Academic Significance and Societal Importance of the Research Achievements |
従来不可能であったバイオフィルムの可視化をベッドサイドで可能としたことにより、これまで経験的に行われてきた「創の清浄化」という最も基本的な創傷ケアに変革をもたらした。これは看護技術の本質である非侵襲的、リアルタイムケアを基本とした、褥瘡感染の病態に迫る本質的で合理的なアセスメント技術といえる。これにより、創傷ケアにかかる患者の負担の軽減ならびに医療費の削減に直結するであろう。
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Biofilm detection by wound blotting can predict slough development in pressure ulcers: a retrospective observational study.2017
Author(s)
Nakagami G, Schultz G, Gibson DJ, Phillips P, Kitamura A, Minematsu T, Miyagaki T, Hayashi A, Sasaki S, Sugama J, Sanada H.
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Journal Title
Wound Repair and Regeneration
Volume: 25
Issue: 1
Pages: 131-138
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] A new approach for performing biofilm detection-based wound care: A preliminary observational study2017
Author(s)
Nakagami G, Kitamura A, Astrada A, Noyori S, Nakai A, Minematsu T, Miyagaki T, Sasaki S, Hayashi C, Sanada H
Organizer
The 26th Japanese Society of Wound, Ostomy and Continence Management
Related Report
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