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High-Volume Collection of Aerosols in India and China using the Originally Developed Cyclone Sampler and Evaluation of Their Health Impacts

Research Project

Project/Area Number 17H04480
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Environmental dynamic analysis
Research InstitutionKeio University

Principal Investigator

Okuda Tomoaki  慶應義塾大学, 理工学部(矢上), 准教授 (30348809)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2019: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2017: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Keywordsエアロゾル / サイクロン / 有害性評価 / 環境分析 / 大気汚染防止・浄化 / 環境質定量化・予測 / PM2.5 / 酸化能 / 粒子状物質 / 生物由来物質
Outline of Final Research Achievements

We installed the high-volume samplers using real impactor and cyclone for collecting aerosol particles in powder form without using a filter to three sites, National Physical Institute, India (New Delhi), Xi’an Jiaotong University (China), and Yokohama, Japan. The number of collected samples were 28 in India, 8 in China, and 23 in Japan. Endotoxin (Lipopolysaccharide, LPS) in the aerosol particles were analyzed, and their concentrations were 11±11 in India, 28±22 in China, and 23±27 in Japan (Mean±SD; unit in EU/mg). The endotoxin concentrations did not differ among three cities, and no clear seasonal trend of the endotoxin concentrations were observed.

Academic Significance and Societal Importance of the Research Achievements

近い将来、人間の早期死亡をもたらす最大の環境要因は大気汚染、特に粒子状物質が最も深刻となることが予測されている。本研究の遂行により、東アジアの複数地点において、フィルターを用いずに粉体として大気粒子状物質を得る体制を構築することができた。さらに、得られた粒子状物質の化学成分と生物由来成分の特徴を明らかにした。今後、得られた粒子を用いて細胞・動物への曝露実験を行うことが可能となった。本研究の成果は、人間の生活の質に直結する呼吸器系や免疫系に対する粒子状物質のリスクの解明に係る研究に資することができる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (33 results)

All 2020 2019 2018 2017 Other

All Int'l Joint Research (6 results) Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (20 results) (of which Int'l Joint Research: 12 results,  Invited: 4 results) Remarks (4 results)

  • [Int'l Joint Research] 西安交通大学(中国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] インド国立物理学研究所(NPLI)(インド)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] インド国立物理学研究所(インド)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] 西安交通大学(中国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] インド国立物理学研究所(インド)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] 西安交通大学(中国)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Chemical Speciation of Chromium in Atmospheric Particulate Matter Collected with Cyclone by XAFS Method2020

    • Author(s)
      齋藤 克知、奥田 知明、長谷川 就一、西田 千春、原 圭一郎、林 政彦
    • Journal Title

      Journal of Japan Society for Atmospheric Environment / Taiki Kankyo Gakkaishi

      Volume: 55 Issue: 2 Pages: 27-33

    • DOI

      10.11298/taiki.55.27

    • NAID

      130007806975

    • ISSN
      1341-4178, 2185-4335
    • Year and Date
      2020-03-10
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Ambient PM2.5 Collected Using Cyclonic Separator from Asian Cities on Human Airway Epithelial Cells2019

    • Author(s)
      Chowdhury Pratiti H.、Honda Akiko、Ito Sho、Okano Hitoshi、Onishi Toshinori、Higashihara Makoto、Okuda Tomoaki、Tanaka Toshio、Hirai Seitarou、Takano Hirohisa
    • Journal Title

      Aerosol and Air Quality Research

      Volume: 19 Issue: 8 Pages: 1808-1819

    • DOI

      10.4209/aaqr.2019.01.0016

    • NAID

      120006884162

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of a high-volume simultaneous sampler for fine and coarse particles using virtual impactor and cyclone techniques2018

    • Author(s)
      Okuda, T., Shishido, D., Terui, Y., Fujioka, K., Isobe, R., Iwaki, Y., Funato, K., Inoue, K.
    • Journal Title

      Asian Journal of Atmospheric Environment

      Volume: 12 Issue: 1 Pages: 78-86

    • DOI

      10.5572/ajae.2018.12.1.078

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Factors responsible for the biological responses of exposure to atmospheric fine and coarse particles collected by cyclone in three Japanese cities2019

    • Author(s)
      Okuda, T., Goto, T., Takano, H., Honda, A., Onishi, T., Tanaka, M., Hasegawa, S., Kameda, T., Tohno, S., Hayashi, M., Hara, K., Nishita-Hara, C., Inoue, K.
    • Organizer
      11th Asian Aerosol Conference (Hong Kong, China)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Comparison of PM2.5 chemical composition collected with cyclone and filter2019

    • Author(s)
      Katori, T., Shishido, D., Okuda, T.
    • Organizer
      11th Asian Aerosol Conference (Hong Kong, China)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chemical Analysis and DTT Assay of Powder Form of Atmospheric Particulate Matter Collected by Cyclone in India and Japan2019

    • Author(s)
      Jiaxin Chen, Tomoaki Okuda
    • Organizer
      11th Asian Aerosol Conference (Hong Kong, China)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chemical speciation of chromium in atmospheric particulate matter collected with filter and cyclone by XAFS method2019

    • Author(s)
      Saito, K., Okuda, T.
    • Organizer
      11th Asian Aerosol Conference (Hong Kong, China)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CYCLEX: Cyclone Collection of Particulate Matter Followed by Exposure Experiments2019

    • Author(s)
      Tomoaki Okuda, Takaaki Goto, Hirohisa Takano, Akiko Honda, Toshinori Onishi, Michitaka Tanaka, Shuichi Hasegawa, Takayuki Kameda, Susumu Tohno, Chiharu Nishita-Hara, Keiichiro Hara, Masahiko Hayashi, Kozo Inoue
    • Organizer
      American Association for Aerosol Research 37th Annual Conference (Portland, Oregon, USA)
    • Related Report
      2019 Annual Research Report
  • [Presentation] Improvement of Cyclone Sampler and Its Performance for Chemical Composition and Toxicity Measurement2019

    • Author(s)
      Takuya Katori, Ayumi Iwata, Daiki Shishido, Yoshihiro Terui, Tomoaki Okuda
    • Organizer
      American Association for Aerosol Research 37th Annual Conference (Portland, Oregon, USA)
    • Related Report
      2019 Annual Research Report
  • [Presentation] インドと日本におけるエアロゾルの大流量捕集と粒子のDTT 酸化能の測定2019

    • Author(s)
      陳嘉欣, 照井凱大, 奥田知明, Shankar G. Aggarwal
    • Organizer
      第36回エアロゾル科学・技術討論会(広島大学・広島県東広島市)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 小型サイクロンによる大気中微小粒子状物質の捕集と有害性評価2019

    • Author(s)
      香取拓也, 岩田歩, 完戸大輝, 照井凱大, 奥田知明
    • Organizer
      第36回エアロゾル科学・技術討論会(広島大学・広島県東広島市)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 神奈川・埼玉・福岡でサイクロン採取された粒子状物質中 Cr の XAFS による化学状態解析2019

    • Author(s)
      齋藤克知,奥田知明,長谷川就一,西田千春,原圭一郎,林政彦
    • Organizer
      第60回大気環境学会年会(東京農工大学・東京都府中市)
    • Related Report
      2019 Annual Research Report
  • [Presentation] Chemical analysis and DTT assay of powder form of atmospheric particles collected by cyclone2018

    • Author(s)
      Terui, Y., Shishido, D., Kanemaru, A., Sato, T., Okuda, T.
    • Organizer
      10th International Aerosol Conference, St. Louis, USA
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characteristics of PM2.5 in India collected by high-volume PM2.5 particle sampler2018

    • Author(s)
      Chen, J., Okuda, T., Aggarwal, S.G.
    • Organizer
      Joint International Symposium of 14th CACGP & 15th IGAC, Takamatsu, Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a small-sized cyclone to collect ultrafine particles in the air2018

    • Author(s)
      Katori, T., Okuda, T.
    • Organizer
      Joint International Symposium of 14th CACGP & 15th IGAC, Takamatsu, Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Factors responsible for the health effects of atmospheric fine and coarse particles by cyclone collection and exposure experiments2018

    • Author(s)
      Okuda, T., Takano, H., Honda, A., Hasegawa, S., Kameda, T., Tohno, S., Onishi, T., Tanaka, M., Hayashi, M., Hara, K., Nishita-Hara, C., Shishido, D., Terui, Y., Sato, T., Inoue, K.
    • Organizer
      China-Japan-Korea Joint International Symposium on Continuously Improvement of Air Quality, 2018 Annual Meeting of AAE-CSES, Qingdao, China
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] インドにおけるPM2.5の大流量捕集と粒子の特徴2018

    • Author(s)
      陳嘉欣,奥田知明,Aggarwal, S.G.
    • Organizer
      第35回エアロゾル科学・技術研究討論会、名古屋大学
    • Related Report
      2018 Annual Research Report
  • [Presentation] サイクロン法により採取された大気エアロゾル粉体のDTT Assayによる酸化能測定2018

    • Author(s)
      照井凱大,完戸大輝,佐藤摘歩実,奥田知明,船戸浩二,井上浩三
    • Organizer
      第35回エアロゾル科学・技術研究討論会、名古屋大学
    • Related Report
      2018 Annual Research Report
  • [Presentation] Development of measurement techniques of physical and chemical characteristics of atmospheric aerosols related to their adverse health effect2018

    • Author(s)
      Okuda, T.
    • Organizer
      Frontiers of Atmospheric Aerosol Studies: Toward the Understanding of Their Health and Climatic Effects
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Measurement of physical and chemical characteristics of atmospheric aerosols related to their adverse health effect2017

    • Author(s)
      Okuda, T.
    • Organizer
      International Symposium on Continuously Improvement of Air Quality: Science, Technology and Policy
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Need of a high-volume PM2.5 sampler for performing better gravimetric measurements and chemical analyses2017

    • Author(s)
      Aggarwal, S.G., Patel, P., Tsai, C.J., Soni, D., Singh, K., Okuda, T., Kotnala, R.K., Ojha, V.N., Aswal, D.K.
    • Organizer
      10th Asian Aerosol Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of the high volume simultaneous sampler for fine and coarse aerosol particles using a combination of virtual impactor and multi-cyclone2017

    • Author(s)
      Okuda, T., Shishido, D, Terui, Y., Funato, K., Inoue, K.
    • Organizer
      10th Asian Aerosol Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] PM2.5を集めて測る ~捕集と特性解明の技術~2017

    • Author(s)
      奥田 知明
    • Organizer
      第7回CSJ化学フェスタ
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Remarks] 環境化学研究室 | 研究内容 | ハイライト【粒子状物質の有害性評価】

    • URL

      https://www.applc.keio.ac.jp/~okuda/research/theme/toxicity.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] 大気粒子の物理化学特性解明と曝露実験による生体有害性評価

    • URL

      https://www.st.keio.ac.jp/education/research/me201803.html

    • Related Report
      2019 Annual Research Report
  • [Remarks]

    • URL

      http://www.applc.keio.ac.jp/~okuda/research/index.html

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://www.applc.keio.ac.jp/~okuda/research/index.html

    • Related Report
      2017 Annual Research Report

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Published: 2017-04-28   Modified: 2021-02-19  

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